User:Tkadm30/Notebook/Endocannabinoids/Anandamide: Difference between revisions

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* Intracellular FABP5 expression result in anandamide trafficking of heteromeric CB1 receptor.
* Intracellular FABP5 expression result in anandamide trafficking of heteromeric CB1 receptor.
* Adenosine antagonism potentiate organized trafficking of anandamide via heteromization of CB1 receptor.
* Adenosine antagonism potentiate organized trafficking of anandamide via heteromization of CB1 receptor.
* Anandamide biosynthesis enhances diuresis. <cite>Paper3</cite>


=== See also ===
=== See also ===
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#Paper2 https://www.ncbi.nlm.nih.gov/pubmed/21719698
#Paper2 https://www.ncbi.nlm.nih.gov/pubmed/21719698
//Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide.
//Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide.
#Paper3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533417/
//Diuretic Effects of Cannabinoids
</biblio>
</biblio>

Revision as of 08:02, 26 February 2017

Intracellular anandamide trafficking as a promoter of neural differentiation acting through selective CB1 binding

The maturation of neural stem cells via fatty-acid binding proteins (FABPs) signaling may require anandamide as a promoter of CB1-dependent neural differentiation. [1]

Differentiation of hippocampal stem cells with synaptamide is induced by intracellular and selective CB1 receptor binding to anandamide. [2]

Notes

  • Allosteric activation of PPAR-RXR heterodimer by anandamide (CB1/TRPV1 receptors) facilitate hippocampal neurogenesis.
  • Intracellular FABP5 expression result in anandamide trafficking of heteromeric CB1 receptor.
  • Adenosine antagonism potentiate organized trafficking of anandamide via heteromization of CB1 receptor.
  • Anandamide biosynthesis enhances diuresis. [3]

See also

References

  1. https://www.ncbi.nlm.nih.gov/pubmed/23372698

    [Paper1]

    Type-1 (CB1) Cannabinoid Receptor Promotes Neuronal Differentiation and Maturation of Neural Stem Cells

  2. https://www.ncbi.nlm.nih.gov/pubmed/21719698

    [Paper2]

    Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide.

  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3533417/

    [Paper3]

    Diuretic Effects of Cannabinoids

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