User:Tkadm30/Notebook/Endocannabinoids/Anandamide: Difference between revisions
From OpenWetWare
(→Notes) |
|||
Line 9: | Line 9: | ||
* Intracellular FABP5 expression may result in anandamide trafficking of heteromeric CB1 receptor. | * Intracellular FABP5 expression may result in anandamide trafficking of heteromeric CB1 receptor. | ||
* Adenosine antagonism may potentiate retrograde trafficking of anandamide via heteromization of CB1 receptor. | * Adenosine antagonism may potentiate retrograde trafficking of anandamide via heteromization of CB1 receptor. | ||
* Anandamide biosynthesis may | * Anandamide biosynthesis may enhance caffeine-induced diuresis. <cite>Paper3</cite> | ||
* Anandamide-oxytocin cross-talk (signal transduction) may modulate cellular stress response/vitamin D gene expression? | * Anandamide-oxytocin cross-talk (signal transduction) may modulate cellular stress response/vitamin D gene expression? | ||
Revision as of 04:46, 28 May 2017
Intracellular anandamide trafficking as a promoter of neurogenesis acting through presynaptic CB1/FABP binding
The maturation and differentiation of neural stem cells via fatty-acid binding proteins (FABPs) signaling may require anandamide as a promoter of CB1-dependent neurogenesis. [1]
Hippocampal neurogenesis with synaptogenic promoter (DHA) is induced by intracellular and presynaptic CB1 receptor binding to anandamide. [2]
Notes
- The allosteric activation of PPAR-RXR heterodimer by anandamide (CB1/TRPV1 receptors) may facilitate hippocampal neurogenesis.
- Intracellular FABP5 expression may result in anandamide trafficking of heteromeric CB1 receptor.
- Adenosine antagonism may potentiate retrograde trafficking of anandamide via heteromization of CB1 receptor.
- Anandamide biosynthesis may enhance caffeine-induced diuresis. [3]
- Anandamide-oxytocin cross-talk (signal transduction) may modulate cellular stress response/vitamin D gene expression?
See also
References
-
Type-1 (CB1) Cannabinoid Receptor Promotes Neuronal Differentiation and Maturation of Neural Stem Cells
-
Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide.
-
Diuretic Effects of Cannabinoids
-
The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway.