User:Etienne Robillard/Notebook/Fmoc protected phenoxyalkylamine synthesis

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The purpose of this page is to investigate the design and method of operation of novel psychotropic
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alkylamines and synthesis with Fmoc protected reagents, including primary and secondary amines
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as organocatalysts for development of synthetic pharmaceutical compounds with an aryl moeity, hence
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refered herein as N,N-substituted arylcyclohexylamines.
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=== Microwave-activated peptide synthesis ===
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* NB: the electromagnetic radio-frequency range most typical wireless devices operates under the FCC standard for communication devices is 2.45 GHz.
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* In fact, most peoples are unaware this operating frequency can modulate Fmoc protected oligos by micro-wave thermal irradiation, thus a remote attacker may exploit this unregulated frequency range to trigger Fmoc-SPPS based orthogonal ligations of N-methyl rich peptides. [[http://www.faqs.org/patents/app/20100305182 1]]
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* http://www.pharmainfo.net/reviews/new-era-field-synthetic-chemistry-microwave-assisted-synthesis
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* http://www.dddmag.com/articles/2011/08/microwave-peptide-synthesis
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* [http://host.madison.com/wsj/news/science/seely-on-science-chemical-agents-wage-war-against-bacteria/article_b5e25710-ed70-11e1-8e6b-0019bb2963f4.html Chemical agents wage war against owners of wireless communication devices operating in the 2.45 GHz spectrum]
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* From gun control to wireless control, unregulation of the S-band frequency is not without risks of abuses from bioterrorists to develop dual-purposes, synthetic bioweapons: http://nanopatentsandinnovations.blogspot.se/2009/11/microwave-manufactures-semiconductor.html
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** '''"The microwave reactor operates at 2.45 GHz and can be adapted to a continuous flow or autosampler system. "'''
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=== Keywords ===
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N-Methyl-d-aspartate receptor; PCP binding site; MK-801; Tetrahydroisoquinolines, AHL, NAND gate, Inverter, Artemisinin, 2.450, ghz, imine, dimer, tryptophane, PVOH, drug delivery, MIT, Langer, Boston Children Hospital, wireless, empathy, apathy, cognition, visual memory, learning,  Robert Langer, MIT, Lanza, Holmes, mefloquine, [http://unknownjournal.wordpress.com/2010/10/06/▼-report-the-kochs-their-nazi-past-american-oil-the-foundation-of-republican-ideology/ Koch Institute],
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=== References ===
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<biblio>
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#Rodriguez-H-2012 pmid=20127857
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#Ludwig-M-Cornelia-E-CE-Hoesl-Klaus-T-KT-Wanner pmid=16675066
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</biblio>
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=== See also ===
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* Lewis Acid Catalysed Pictet Spengler Formation of Substituted 1,2,3,4-Tetrahydroisoquinolines.
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