User:Etienne Robillard/Notebook/Isocyanide

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=== Ugi route to Wilmslow ===
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{{deleteme}}
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# Step 1: Protonation of the isocyanide carbonyl ('''C=O''') to yield a nucleophilic '''[[User:Etienne_Robillard/Notebook/Schiff_base|Schiff base]]''' via Hoffman/Ugi reaction: O+2ROH = -RN
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=== References ===
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<biblio>
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#Hoffman1 pmid=16953613
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#Hoffman2 http://www.chem.ucalgary.ca/courses/351/Carey5th/Ch17/ch17-3-4-2.html
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#Hoffman3 http://www2.chemistry.msu.edu/faculty/reusch/virttxtjml/aldket1.htm
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#Wikipedia http://en.wikipedia.org/wiki/Isonitrile
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</biblio>
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