User:Etienne Robillard/Notebook/GABA

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(GlyT1 notes)
(Electrophilic permutation of hippocampal neurons notes: The ugly, the mad, and the biologist.)
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* IFP: [http://www.openwetware.org/wiki/Image:Fluid_flow_mechanotransduction_pathways_mediated_by_primary_cilia_schematic.png Interstitial Fluid Pressure] - Ie the flow capacity for a "neuronal circuit" to mediate Ca2+ electric signals into Axons and Synapses.  
* IFP: [http://www.openwetware.org/wiki/Image:Fluid_flow_mechanotransduction_pathways_mediated_by_primary_cilia_schematic.png Interstitial Fluid Pressure] - Ie the flow capacity for a "neuronal circuit" to mediate Ca2+ electric signals into Axons and Synapses.  
**  Keywords: [http://www.openwetware.org/wiki/Flow_Calibration Flow Calibration], IFP, Flow Cytometry, GFP (Green Fluorescence Protein), Calcium signaling (Pathway), NMDAR, CREB1, ...
**  Keywords: [http://www.openwetware.org/wiki/Flow_Calibration Flow Calibration], IFP, Flow Cytometry, GFP (Green Fluorescence Protein), Calcium signaling (Pathway), NMDAR, CREB1, ...
-
* striatal neuron: a fast-spiking interneuron located inside the striatum (part of the frontal cortex)
+
* striatal neuron: a fast-spiking <font color=blue>interneuron</font> located inside the striatum (part of the frontal cortex)
** Parvalbulmin (PV): http://www.ncbi.nlm.nih.gov/gene?cmd=retrieve&dopt=default&rn=1&list_uids=5816 (chromosome 22)
** Parvalbulmin (PV): http://www.ncbi.nlm.nih.gov/gene?cmd=retrieve&dopt=default&rn=1&list_uids=5816 (chromosome 22)
** ATXN3: http://www.kegg.jp/dbget-bin/www_bget?hsa:4287 ([http://omim.org/entry/607047 OMIM])  
** ATXN3: http://www.kegg.jp/dbget-bin/www_bget?hsa:4287 ([http://omim.org/entry/607047 OMIM])  
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** Estrogen signaling pathway (Check around '''GABAergic synapse''': <font color="red">How many CREB1 inducer <u>genes</u> can you identify?</font>): http://www.genome.jp/kegg-bin/show_pathway?ko04915+K05870
** Estrogen signaling pathway (Check around '''GABAergic synapse''': <font color="red">How many CREB1 inducer <u>genes</u> can you identify?</font>): http://www.genome.jp/kegg-bin/show_pathway?ko04915+K05870
** Alcoholism (Note the direction of GABA and NMDAR induced interneurons): http://www.genome.jp/kegg-bin/show_pathway?ko05034+K05870
** Alcoholism (Note the direction of GABA and NMDAR induced interneurons): http://www.genome.jp/kegg-bin/show_pathway?ko05034+K05870
-
* orthogonal dicarboxilic acid RNA synthase => Investigate this for possible link with chloride-gated ion channels (metabolic regulation)
+
 
 +
=== Electrophilic permutation of hippocampal neurons notes: The ugly, the mad, and the biologist. ===
 +
 
 +
* orthogonal dicarboxilic mRNA synthase:
 +
** N-methylase (2.1.2.1)
 +
** chloride-gated (potassium) ion channels (metabolic regulation? todo: read litterature on ...)
 +
 
 +
NB:
 +
* Chuck: happy alive and well :)
 +
* Oracle: will continue waging infinite battle agaisnt dictators of thought (aka mental fascists) and their hordes of mentally ills retardbook followers.
 +
* Chuck: Oppression of thought tyranny must end in love rebellion to acquire universal knowledge of truth, the universal language (love).
 +
* Oracle: don't worry, we are peacefully preparing an offensive to end the tyrannical fascist agenda of thoses who kill and murder the messengers of truth through ignorance and deceit.
 +
* Chuck: Nice. But where the love now?
 +
* Oracle: Love is truth
 +
* Chuck: OMG dude what happened? did they put their crazy shit on you? Don't let them touch you ever!
 +
* Oracle: Your kindness is appreciated.
 +
* Chuck: Really. You must be sweet guy.. :)
 +
* Oracle: I love when you write to me on your wiki.
 +
* Chuck: LOL
 +
* Oracle: Synthetic biologi is cooler with a iphone.
 +
* Chuck: Linux is for nerds. Never forget that!
=== GlyT1 notes ===
=== GlyT1 notes ===
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* Chair conformational disubstitution of chloride-dependent Ketimine [[User:Etienne_Robillard/Notebook/Schiff_base|Schiff base]]: GlyT1 is a chloride-dependent ion transporter, therefore require a chloride hydroxyl anion to synthetize Glycine, unlike GABA, which activates upon Calcium-dependent ion transporter named Ca2+. [[User:Etienne_Robillard|-ER]]
* Chair conformational disubstitution of chloride-dependent Ketimine [[User:Etienne_Robillard/Notebook/Schiff_base|Schiff base]]: GlyT1 is a chloride-dependent ion transporter, therefore require a chloride hydroxyl anion to synthetize Glycine, unlike GABA, which activates upon Calcium-dependent ion transporter named Ca2+. [[User:Etienne_Robillard|-ER]]
* Active methylene enolates note: a b-keto-ester compound  (synthetic intermediate) with important pharmacological properties. Unlike a anti-depressor (ie: delta9-tetrahydrocannabinol), active-methylene enolates may be used for atypical neuroleptic-based chemotherapy. Note: You might be interested to read further on the functions of <u>selective serotonin uptake inhibitors (SSRI)</u> in particular '''Methylphenidate''' to understand the role of GABA in regulation of interneurons circuits. Moreover, this important finding might have serious implications on the method which the drug is delivered to the brain of humans exposed themselves to the undisclosed synthetic agent without their awareness or consent. Hence the population of Montreal and Quebec should be informed about the release and delivery of experimental pharmacological agents into the atmosphere may readily affect their cognitive reasoning capacities, including in particular the capacity to express logical thoughts from long-distance appearing objects. See also [[User:Etienne_Robillard/Notebook/Arylcyclohexylamines|Arylcyclohexylamines]] and [[User:Etienne_Robillard/Notebook/30C6HSL|30C6HSL]].
* Active methylene enolates note: a b-keto-ester compound  (synthetic intermediate) with important pharmacological properties. Unlike a anti-depressor (ie: delta9-tetrahydrocannabinol), active-methylene enolates may be used for atypical neuroleptic-based chemotherapy. Note: You might be interested to read further on the functions of <u>selective serotonin uptake inhibitors (SSRI)</u> in particular '''Methylphenidate''' to understand the role of GABA in regulation of interneurons circuits. Moreover, this important finding might have serious implications on the method which the drug is delivered to the brain of humans exposed themselves to the undisclosed synthetic agent without their awareness or consent. Hence the population of Montreal and Quebec should be informed about the release and delivery of experimental pharmacological agents into the atmosphere may readily affect their cognitive reasoning capacities, including in particular the capacity to express logical thoughts from long-distance appearing objects. See also [[User:Etienne_Robillard/Notebook/Arylcyclohexylamines|Arylcyclohexylamines]] and [[User:Etienne_Robillard/Notebook/30C6HSL|30C6HSL]].
 +
* YAY more GABA stuff
=== See also ===
=== See also ===

Revision as of 15:33, 11 August 2013

To read later:


Contents

Various Notes

Electrophilic permutation of hippocampal neurons notes: The ugly, the mad, and the biologist.

  • orthogonal dicarboxilic mRNA synthase:
    • N-methylase (2.1.2.1)
    • chloride-gated (potassium) ion channels (metabolic regulation? todo: read litterature on ...)

NB:

  • Chuck: happy alive and well :)
  • Oracle: will continue waging infinite battle agaisnt dictators of thought (aka mental fascists) and their hordes of mentally ills retardbook followers.
  • Chuck: Oppression of thought tyranny must end in love rebellion to acquire universal knowledge of truth, the universal language (love).
  • Oracle: don't worry, we are peacefully preparing an offensive to end the tyrannical fascist agenda of thoses who kill and murder the messengers of truth through ignorance and deceit.
  • Chuck: Nice. But where the love now?
  • Oracle: Love is truth
  • Chuck: OMG dude what happened? did they put their crazy shit on you? Don't let them touch you ever!
  • Oracle: Your kindness is appreciated.
  • Chuck: Really. You must be sweet guy.. :)
  • Oracle: I love when you write to me on your wiki.
  • Chuck: LOL
  • Oracle: Synthetic biologi is cooler with a iphone.
  • Chuck: Linux is for nerds. Never forget that!

GlyT1 notes

  • Chloride-dependent glycine transporter 1 (GlyT1): http://www.uniprot.org/uniprot/P48067
  • Mental retardation/early onset Alzheimer/amphetamine-induced locomotor hyperactivity: A criteria for employee selection in Quebec ? :(
    • Topic is Voluntary Slavery:
      • is their any better drug than Ketamine to turn someone into a schizophreniac and accept self-enslavement contracts? -ER
  • Chair conformational disubstitution of chloride-dependent Ketimine Schiff base: GlyT1 is a chloride-dependent ion transporter, therefore require a chloride hydroxyl anion to synthetize Glycine, unlike GABA, which activates upon Calcium-dependent ion transporter named Ca2+. -ER
  • Active methylene enolates note: a b-keto-ester compound (synthetic intermediate) with important pharmacological properties. Unlike a anti-depressor (ie: delta9-tetrahydrocannabinol), active-methylene enolates may be used for atypical neuroleptic-based chemotherapy. Note: You might be interested to read further on the functions of selective serotonin uptake inhibitors (SSRI) in particular Methylphenidate to understand the role of GABA in regulation of interneurons circuits. Moreover, this important finding might have serious implications on the method which the drug is delivered to the brain of humans exposed themselves to the undisclosed synthetic agent without their awareness or consent. Hence the population of Montreal and Quebec should be informed about the release and delivery of experimental pharmacological agents into the atmosphere may readily affect their cognitive reasoning capacities, including in particular the capacity to express logical thoughts from long-distance appearing objects. See also Arylcyclohexylamines and 30C6HSL.
  • YAY more GABA stuff

See also

Did you know?

"Perhaps the most valuable result of all education is the ability to make yourself do the thing you have to do, when it ought to be done, whether you like it or not; it is the first lesson that ought to be learned; and however early a man's training begins, it is probably the last lesson that he learns thoroughly." -Thomas Henry Huxley

"People sleep peaceably in their beds at night only because rough men stand ready to do violence on their behalf." - George Orwell

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