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== Hypercomputation ==
== Neuronal hypercomputation ==
===Artificial hypercomputation===
* Feasibility of artificial hypercomputation in humans?
 
 
 
=== Cannabimimetic hypercomputation ===
Endocannabinoid-mediated synaptic hypercomputation is caused by the pharmacological activation of cannabinoid receptors (CB1, CB2)
controlling neuronal phase coherence (synchronized gamma oscillations) at (dopaminergic) interneuron networks. <cite>Paper7</cite>
 
Anandamide-dopamine cross-talk:
* Review: [https://www.ncbi.nlm.nih.gov/pubmed/20632964 GPCR receptor heteromerization]
** Anandamide-dopamine heteromeric transactivation may potentiate synaptic hypercomputation in the gamma band. <cite>Paper2</cite><cite>Paper5</cite>
* Fast synaptic inhibition by retrograde signaling may trigger synchronized gamma oscillations in the hippocampus. <cite>Paper5</cite>
 
===Neuroholographic hypercomputation===
 
Imagination is more important than knowledge:
* [https://en.wikipedia.org/wiki/Holonomic_brain_theory Other studies have demonstrated the possibility that biophoton emission (biological electrical signals that are converted to weak electromagnetic waves in the visible range) may be a necessary condition for the electric activity in the brain to store holographic images.]
* Myelinated axons serving as biophotonic waveguides: The brain may consolidate neuroholographic informations via optical communication channel within the CNS.
 
Research subtopics:
* Tubulin heterodimerization dynamics
* Dopaminergic interneurons


=== Synaptic hypercomputation ===
=== Synaptic hypercomputation ===


The Synaptic Hypercomputation (SH) hypothesis states that the continuous phase transition of conscious states evolve via discrete computations mediated by neurexins and neuroligins proteins. This non-classical neurocomputational model is controlled by [[User:Etienne_Robillard/Notebook/Synaptic_exocytosis|synaptic exocytosis]], generating neural criticality in the CNS.
The synaptic hypercomputation (SH) hypothesis states that the phase coherence of neural communication (synaptic latency) may emerges via long-range synchronicity in the gamma range. In specific, this neurocomputational model is controlled by synaptic (dopamine?) exocytosis, regulating phase-dependent presynaptic action potential (synaptic waveform) in a quantum system. <cite>Paper1</cite>
 
== Photosynthetic hypercomputation ==


=== Pharmacological hypercomputation ===
Quantum coherence in photosynthetic systems is evidence of biophotonic-like (coherent) energy transfer in plants mitochondria.


* Is pharmacological hypercomputation (PH) a dopamine-mediated synaptic function? (exocytosis)
== Neuronal phase coherence and synchronicity ==
* Cannabinoids may rewire the brain connectivity by enhancing functional neurogenesis and [http://www.thenakedscientists.com/forum/index.php?topic=68779 cognitive intelligence].


=== Heteromeric transactivation of adenosine-CB1 receptors ===
Neuronal phase coherence is non-local "quantum-like" entanglement because long-range synchronicity is critical for optimal biophotonic communication in the gamma band. <cite>Paper3</cite>
How adenosine-CB1 heteromeric transactivation potentiate synaptic hypercomputation?


===Neurexin-mediated trans-synaptic exocytosis===
== Notes ==
Could retrograde signaling promote synaptic proteins synthesis ? https://www.ncbi.nlm.nih.gov/pubmed/17035546
* Synaptic binding (latency?) is a phase-dependent coherent effect of exocytosis?
* Anandamide/dopamine cross-talk fine-tune synaptic binding of intracellular CB1 receptors?


== Discussion ==
== Discussion ==
* [http://www.thenakedscientists.com/forum/index.php?topic=65959 Is neuronal hypercomputation a form of synaptic quantum tunnelling?]
* [https://www.thenakedscientists.com/forum/index.php?topic=65959 Is neuronal hypercomputation a form of synaptic quantum tunnelling?]
* [http://www.thenakedscientists.com/forum/index.php?topic=66666 What is Biological Hypercomputation (BH)?]
 
* [http://www.thenakedscientists.com/forum/index.php?topic=67251.0 What is the speed of consciousness?]
* [https://www.thenakedscientists.com/forum/index.php?topic=67261.0 Is self-organized criticality (SOC) an evidence of biological hypercomputation?]
* [http://www.thenakedscientists.com/forum/index.php?topic=67261.0 Is self-organized criticality (SOC) an evidence of biological hypercomputation?]
* [https://www.thenakedscientists.com/forum/index.php?topic=68596.0 Is synaptic hypercomputation a function of exocytosis?]
* [http://www.thenakedscientists.com/forum/index.php?topic=67550 What is synaptic hypercomputation?]
* [https://www.thenakedscientists.com/forum/index.php?topic=66666 What is biological hypercomputation?]
* [http://www.thenakedscientists.com/forum/index.php?topic=67608.0 What is biological phase coherence?]
* [https://www.thenakedscientists.com/forum/index.php?topic=67550 What is synaptic hypercomputation?]
* [https://www.thenakedscientists.com/forum/index.php?topic=67608.0 What is biological phase coherence?]
* [https://www.thenakedscientists.com/forum/index.php?topic=70184 What is holographic memory?]
* [https://www.thenakedscientists.com/forum/index.php?topic=69093  Where is consciousness in the brain?]
* [http://www.scienceforums.net/topic/102100-neuronal-phase-coherence-and-synchronicity/ Neuronal phase coherence and synchronicity]
 
== References ==
<biblio>
#Paper1 http://www.sciencedirect.com/science/article/pii/S0896627315008235
//Rhythms for Cognition: Communication through Coherence
#Paper2 http://molpharm.aspetjournals.org/content/67/5/1697.short
//Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Enhances Heterodimer Formation: A Mechanism for Receptor Cross-Talk?
#Paper3 http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003723
//Phase-Coherence Transitions and Communication in the Gamma Range between Delay-Coupled Neuronal Populations
#Paper4 http://iopscience.iop.org/article/10.1088/1742-6596/306/1/012075/meta
//Plausibility of quantum coherent states in biological systems
#Paper5 http://www.pnas.org/content/99/20/13222.full
//Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks
#Paper7 https://www.ncbi.nlm.nih.gov/pubmed/17180162
//Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks.
#Paper8 https://www.ncbi.nlm.nih.gov/pubmed/14962620
//Biophotons, microtubules and CNS, is our brain a "holographic computer"?
#Paper9 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978290/
//Human high intelligence is involved in spectral redshift of biophotonic activities in the brain
</biblio>
 
== See also ==
* [[User:Etienne_Robillard/Notebook/Endocannabinoids|Endocannabinoids Notebook]]
* [[User:Etienne_Robillard/Notebook/Synaptic_exocytosis|Synaptic exocytosis Notebook]]
* [[User:Etienne_Robillard/Notebook/Dopamine|Dopamine Notebook]]

Latest revision as of 04:23, 9 February 2019

This page has moved here

Neuronal hypercomputation

Artificial hypercomputation

  • Feasibility of artificial hypercomputation in humans?


Cannabimimetic hypercomputation

Endocannabinoid-mediated synaptic hypercomputation is caused by the pharmacological activation of cannabinoid receptors (CB1, CB2) controlling neuronal phase coherence (synchronized gamma oscillations) at (dopaminergic) interneuron networks. [1]

Anandamide-dopamine cross-talk:

  • Review: GPCR receptor heteromerization
    • Anandamide-dopamine heteromeric transactivation may potentiate synaptic hypercomputation in the gamma band. [2][3]
  • Fast synaptic inhibition by retrograde signaling may trigger synchronized gamma oscillations in the hippocampus. [3]

Neuroholographic hypercomputation

Imagination is more important than knowledge:

Research subtopics:

  • Tubulin heterodimerization dynamics
  • Dopaminergic interneurons

Synaptic hypercomputation

The synaptic hypercomputation (SH) hypothesis states that the phase coherence of neural communication (synaptic latency) may emerges via long-range synchronicity in the gamma range. In specific, this neurocomputational model is controlled by synaptic (dopamine?) exocytosis, regulating phase-dependent presynaptic action potential (synaptic waveform) in a quantum system. [4]

Photosynthetic hypercomputation

Quantum coherence in photosynthetic systems is evidence of biophotonic-like (coherent) energy transfer in plants mitochondria.

Neuronal phase coherence and synchronicity

Neuronal phase coherence is non-local "quantum-like" entanglement because long-range synchronicity is critical for optimal biophotonic communication in the gamma band. [5]

Notes

  • Synaptic binding (latency?) is a phase-dependent coherent effect of exocytosis?
  • Anandamide/dopamine cross-talk fine-tune synaptic binding of intracellular CB1 receptors?

Discussion

References

  1. [Paper7]

    Synaptic mechanisms of synchronized gamma oscillations in inhibitory interneuron networks.

  2. [Paper2]

    Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Enhances Heterodimer Formation: A Mechanism for Receptor Cross-Talk?

  3. [Paper5]

    Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks

  4. [Paper1]

    Rhythms for Cognition: Communication through Coherence

  5. [Paper3]

    Phase-Coherence Transitions and Communication in the Gamma Range between Delay-Coupled Neuronal Populations

  6. [Paper4]

    Plausibility of quantum coherent states in biological systems

  7. [Paper8]

    Biophotons, microtubules and CNS, is our brain a "holographic computer"?

  8. [Paper9]

    Human high intelligence is involved in spectral redshift of biophotonic activities in the brain

See also