User:Tkadm30/Notebook/Hypercomputation

Hypercomputation

Synaptic hypercomputation

The Synaptic Hypercomputation (SH) hypothesis states that the phase coherence of neural communication (synaptic plasticity) may emerges via long-range synchrony in the gamma range. This non-classical neurocomputational model is controlled by synaptic exocytosis, regulating neural communication in the brain. [1]

Pharmacological hypercomputation

• Pharmacological hypercomputation (PH): a dopamine-CB1 cross-talk?
  • Review: GPCR receptor heteromerization
• Heteromeric transactivation of dopamine-CB1 receptors:
  • Dopamine-CB1 heteromeric transactivation may potentiate synaptic hypercomputation in the gamma band. [2]

Neuronal phase coherence and synchronicity

Neuronal phase coherence is "quantum-like" because long-range synchronicity is critical for optimal communication in the gamma band. [3]

Discussion

• Is neuronal hypercomputation a form of synaptic quantum tunnelling?
• What is biological hypercomputation?
• Is self-organized criticality (SOC) an evidence of biological hypercomputation?
• What is synaptic hypercomputation?
• Is synaptic hypercomputation a function of exocytosis?
• What is biological phase coherence?
• Neuronal phase coherence and synchronicity

References

1. http://www.sciencedirect.com/science/article/pii/S0896627315008235

   Rhythms for Cognition: Communication through Coherence

2. http://molpharm.aspetjournals.org/content/67/5/1697.short

   Concurrent Stimulation of Cannabinoid CB1 and Dopamine D2 Receptors Enhances Heterodimer Formation: A Mechanism for Receptor Cross-Talk?

3. http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003723

   Phase-Coherence Transitions and Communication in the Gamma Range between Delay-Coupled Neuronal Populations

See also

• Endocannabinoids Notebook