User:Tkadm30/Notebook/Paliperidone/2013/10/10: Difference between revisions
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# Study (Mg+ATP) hydrolysis further | # Study (Mg+ATP) hydrolysis further | ||
## include notes about AU-bound metal catalysts, OPH '''hydrolase''' (AuNP hydrosols) | ## include notes about AU-bound metal catalysts, OPH '''hydrolase''' (AuNP hydrosols) | ||
## Take notes about serine <font color=blue>racemase</font color> ([http://www.uniprot.org/uniprot/Q9GZT4 Uniprot]) | ## Take notes about serine <font color=blue>racemase</font color> ([http://www.uniprot.org/uniprot/Q9GZT4 Uniprot]. Note: "Allosterically activated by magnesium, and possibly also other divalent metal cations. Allosterically activated by ATP, ADP or GTP. Competitively inhibited by malonate.") | ||
==See also== | ==See also== | ||
[[User:Etienne_Robillard/Notebook/OPH|OPH Notebook]] | [[User:Etienne_Robillard/Notebook/OPH|OPH Notebook]] |
Revision as of 12:55, 17 October 2013
9-OH (risperidone) degradation scrachpad
- Todo:
- Investigate CYP2D6
- Establish Role of Aldehyde oxidase in paliperidone metabolite degradation
- Confirm degradation of metabolite vs no inhibitor (as for PLP biosynthesis from 9-oh risperidone...)
- Study (Mg+ATP) hydrolysis further
- include notes about AU-bound metal catalysts, OPH hydrolase (AuNP hydrosols)
- Take notes about serine racemase (Uniprot. Note: "Allosterically activated by magnesium, and possibly also other divalent metal cations. Allosterically activated by ATP, ADP or GTP. Competitively inhibited by malonate.")