User:Tkadm30/Notebook/Research: Difference between revisions
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=== Intracellular delivery of synaptamide to neurons by endocannabinoids === | === Intracellular delivery of synaptamide to neurons by endocannabinoids === | ||
This notebook propose a experimental method for delivery of | This notebook propose a experimental method for delivery of | ||
DHA to hippocampal stem/progenitor cells using | synaptamide (DHA) to hippocampal stem/progenitor cells (NSPCs) using endogenous retrograde signaling. | ||
* [[User:Etienne_Robillard/Notebook/Endocannabinoids|Endocannabinoid Notebook]] | * [[User:Etienne_Robillard/Notebook/Endocannabinoids|Endocannabinoid Notebook]] | ||
Revision as of 04:21, 17 October 2016
Research Interests
- Aluminium-induced oxidative stress and chronic neuroinflammation of the CNS
- Gulf war syndrome
- Glutamatergic system/neurotransmission
- Glutamate-induced excitotoxicity
- Glutaminase
- Astrocytes/mitochondria
- CB1 expression in hippocampal astrocytes and mitochondria
- Intracellular DHA delivery to striatal neurons
- Neuroprotective effects of PPAR-gamma agonists
- Extracellular ATP releases/ATP-mediated gliotransmission
- Effects of adenosine antagonism on retrograde synaptic activity
- Neuroprotection by endocannabinoids of the hippocampus
- Adult hippocampal neurogenesis regulation by CB1 receptor
- Endocannabinoid-mediated neuroprotection against synthetic neurotoxicants of the CNS
- Intrinsic brain activity modulation by atypical antipsychotics
- Drug-induced parkinsonism/schizophrenia (neuronal injury)
- Dopamine hypersensitivity
- Interneuronal quantum coherence in microtubules: Implications for quantum processing of consciousness and free will
- Orch OR theory of consciousness
- Neuronal morphogenesis and maturation
- Synaptogenesis
- Monoamine oxidase inhibitors
- Monoaminergic neurotransmission
- Synaptic quantum tunnelling
- Supramolecular properties of water in biological systems
- Vibrational spectrum of biological water activity
- Biological hypercomputation
- Neuronal phase coherence of synaptic hypercomputation
- Long-term memory formation
- Vitamin D binding protein
- Fatty acid binding proteins
- Self-organized criticality (SOC) in microtubules dynamics
- Biological utilization of quantum nonlocality
- Neurexins/neuroligins modulation of endocannabinoid signaling
- Chronic obstructive pulmonary disease (COPD)
- Accumulative effects of metal oxide nanoparticles exposure on AECOPD.
- Regulation of homeostatic synaptic plasticity by endocannabinoids
- Phase-transition-driven synaptic exocytosis and neurotransmission
- Synaptic phase transition
- Reactive microgliosis
- microglial internalization
Retrograde signaling as a novel neuroprotection platform
The neuropsychological aspects of endocannabinoid based neuroprotection has emerged as a mature research area. My current research aim to investigate methods for exploiting the endocannabinoid levels for neuroprotection purpose.
Intracellular delivery of synaptamide to neurons by endocannabinoids
This notebook propose a experimental method for delivery of synaptamide (DHA) to hippocampal stem/progenitor cells (NSPCs) using endogenous retrograde signaling.
Purinergic effects of DHA on neurotransmission, a putative endocannabinoid induced by P2X7 agonists
P2X7 receptor mediate synaptogenic DHA signaling and intracellular signal transduction pathways relevant to PPAR-induced neural differentiation. Hence, intracellular THC delivery may induce PPAR-dependent activity for DHA-mediated neural differentiation and proliferation of hippocampal progenitor cells through modulation of P2X7 receptor.
Neuroprotective effects of cannabinoids after traumatic brain injury and drug-induced neuronal damage
Programming of hippocampal progenitor cells by anandamide trafficking
Hypercomputation in living organisms
I aim to understand how biological hypercomputation evolved in living organisms.