User:Etienne Robillard/Notebook/Rhodopsin

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(Unresolved questions)
(Unresolved questions)
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== Unresolved questions ==
== Unresolved questions ==
* Question 1: In the expression "'''blind as a bat'''", is the bat blindness a permanent or temporary phenomenon and '''how''' could you assert this is related to cGMP/ATP based phosphorylation of the Rhodopsin kinase?
* Question 1: In the expression "'''blind as a bat'''", is the bat blindness a permanent or temporary phenomenon and '''how''' could you assert this is related to cGMP/ATP based phosphorylation of the Rhodopsin kinase?
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* '''Answer''': Temporary! The bat can recover its vision if the GABA receptor is cleared from cAMP/ATP dependent competitive ligands, thus allowing GPCR based signal transduction to occur normally. [[http://www.reactome.org/entitylevelview/PathwayBrowser.html#DB=gk_current&FOCUS_SPECIES_ID=48887&FOCUS_PATHWAY_ID=500792&ID=419426 1]] Notice also that the S1PR4 gene is a '''near-neighboor''' of the Cannabinoid receptors!
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* '''Answer''': Temporary! The bat can recover its vision if the GABA receptor is cleared from cAMP/ATP dependent competitive ligands, thus allowing GPCR based signal transduction to occur normally. [[http://www.reactome.org/entitylevelview/PathwayBrowser.html#DB=gk_current&FOCUS_SPECIES_ID=48887&FOCUS_PATHWAY_ID=500792&ID=419426 1]] Notice also that the S1PR4 gene is a '''near-neighboor''' of the Cannabinoid receptors! (Hint hint)

Revision as of 21:34, 25 March 2013

References on Rhodopsin

Unresolved questions

  • Question 1: In the expression "blind as a bat", is the bat blindness a permanent or temporary phenomenon and how could you assert this is related to cGMP/ATP based phosphorylation of the Rhodopsin kinase?
  • Answer: Temporary! The bat can recover its vision if the GABA receptor is cleared from cAMP/ATP dependent competitive ligands, thus allowing GPCR based signal transduction to occur normally. [1] Notice also that the S1PR4 gene is a near-neighboor of the Cannabinoid receptors! (Hint hint)
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