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| '''Work-in-progress. Please correct any errors found.'''
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| __TOC__
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| == Hypothesis ==
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| 1. The biological impacts of aerosolized nanoparticles (ANP) are poorly understood.
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| 2. The cytotoxicity of nanoparticle-based stratospheric aerosol injection on human health require further investigations.
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| 3. The differential effects of highly dispersed aerosols (HDA) on immune system, lung function, chronic inflammation, and Alzheimer pathogenesis require additional research. <cite>Gilmour-2004</cite>
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| 4. Microglial activation is implicated in the aluminium-induced neurotoxicity of aerosolized nanoparticles.
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| == Clinical effects of clandestine geoengineering activity ==
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| === Cardiovascular system ===
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| * Effects of particulate matter (PM2.5) air pollution on cardiovascular disease <cite>Brook-2010</cite>
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| ** Increase in blood pressure <cite>Balasubramanian-2013</cite>
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| === Respiratory system ===
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| * AECOPD <cite>Lei-2015</cite>
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| * Lung cancer <cite>Hamra-2014</cite>
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| === Brain/CNS ===
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| * Alzheimer <cite>Jung-2015</cite>
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| * PM2.5 exposure may cause neuroinflammation and oxidative stress. <cite>Lei-2015</cite><cite>Liu-2015</cite><cite>Riva-2011</cite><cite>Levesque-2011</cite>
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| ** PM2.5 exposure induce selective neurotoxicity through glutamatergic signaling and increase NMDA-induced excitotoxicity. <cite>Liu-2015</cite><cite>Morgan-2011</cite>
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| * Dopaminergic/serotonergic signaling upregulation?
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| === Lymphatic system ===
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| * Lipid peroxidation and oxidative DNA damage. <cite>Ambroz-2016</cite>
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| == Cognitive infiltration evidences ==
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| * Facebook Deception: [[User:Etienne_Robillard/Notebook/chim_trills_notebook/2014/12/14|Notebook]]
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| == Notes ==
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| * Aerosolized nanoparticles:
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| ** [http://www.energy.psu.edu/sites/default/files/files/JetFuels.pdf Advanced Thermally Stable Jet Fuels]
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| ** [http://www.energy.psu.edu/sites/default/files/files/coalbased_jetfuel.pdf The Coal-Based Jet Fuel Program]
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| ** [http://web.stanford.edu/group/pitsch/publication/ColketJet_Fuel_Surrogate_AIAA_2007.pdf Jet Fuel Surrogate Research]
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| * Discussion:
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| ** [http://www.thenakedscientists.com/forum/index.php?topic=68004 Do coal-based jet fuel (JP-900) emit ultrafine particles?]
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| ** [http://www.thenakedscientists.com/forum/index.php?topic=67942 Is coal fly ash a synthetic compound?]
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| ** [http://www.thenakedscientists.com/forum/index.php?topic=67302 Should we ban geoengineering?]
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| ** [http://www.thenakedscientists.com/forum/index.php?topic=68061 What is the Gulf War syndrome?]
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| ** [http://www.thenakedscientists.com/forum/index.php?topic=68101 What is a jet fuel surrogate?]
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| * Documentation:
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| ** [https://en.wikipedia.org/wiki/Dodecane Dodecane (Wikipedia)]
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| ** [https://en.wikipedia.org/wiki/Ethylbenzene Ethylbenzene (Wikipedia)]
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| ** [http://www.ncbi.nlm.nih.gov/gene/2744 Glutaminase]
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| ** [http://www.ncbi.nlm.nih.gov/pubmed/?term=gulf+war+syndrome Gulf War syndrome (PubMed search)]
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| ** [https://en.wikipedia.org/wiki/Gulf_War_syndrome Gulf War syndrome (Wikipedia)]
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| ** [https://en.wikipedia.org/wiki/Methylcyclohexane Methylcyclohexane (Wikipedia)]
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| == Resources ==
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| * [[User:Etienne_Robillard/Notebook/chim_trills_notebook/Introduction|Introduction]]
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| * [[User:Etienne_Robillard/Notebook/Brainstorming|Brainstorming]]
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| * [[User:Etienne_Robillard/Notebook/chim_trills_notebook/Model|Model]]
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| * [[User:Etienne_Robillard/Notebook/Photographic_evidences|Photographic evidences]]
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| * [[User:Etienne_Robillard/Notebook/chim_trills_notebook/Research|Research]]
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| == Keywords ==
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| aerosol, bioaerosol, nanoparticles, aluminium oxide, particulate matter, PM2.5, aerosolized jet fuel, gulf war syndrome, chronic neuroinflammation, vapor phase oxidation, hydrocarbons, dodecanol
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| == Support this project ==
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| This project is entirely financed by personal donations. To support this project, use the following link
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| to donate money via Paypal: https://paypal.me/EtienneRobillard
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| == References ==
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| <biblio>
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| #Herndon-2015 http://www.mdpi.com/1660-4601/12/8/9375/htm
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| //Evidence of Coal-Fly-Ash Toxic Chemical Geoengineering in the Troposphere: Consequences for Public Health
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| #Herndon-2016 http://nuclearplanet.com/frontiers1.pdf
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| //Human and Environmental Dangers Posed by Ongoing Global Tropospheric Aerosolized Particulates for Weather Modification.
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| #Gilmour-2004 pmid=15061611
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| //Differential pulmonary inflammation and in vitro cytotoxicity of size-fractionated fly ash particles from pulverized coal combustion.
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| #Brook-2010 pmid=20458016
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| //Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association.
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| #Jung-2015 pmid=25310992
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| //Ozone, particulate matter, and newly diagnosed Alzheimer's disease: a population-based cohort study in Taiwan.
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| #Lei-2015 http://journal.frontiersin.org/article/10.3389/fphys.2015.00294/full
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| //Fine particulate matter in acute exacerbation of COPD.
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| #Hamra-2014 pmid=24911630
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| //Outdoor particulate matter exposure and lung cancer: a systematic review and meta-analysis.
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| #Liu-2015 pmid=25913161
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| //Macrophages treated with particulate matter PM2.5 induce selective neurotoxicity through glutaminase-mediated glutamate generation.
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| #Riva-2011 pmid=21506876
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| //Low dose of fine particulate matter (PM2.5) can induce acute oxidative stress, inflammation and pulmonary impairment in healthy mice.
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| #Levesque-2011 pmid=21561831
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| //Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity.
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| #Morgan-2011 pmid=21724521
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| //Glutamatergic neurons in rodent models respond to nanoscale particulate urban air pollutants in vivo and in vitro.
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| #Cheng-2010 http://www.tandfonline.com/doi/abs/10.1080/027868201753306714
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| //Chemical Composition of Aerosols from Kerosene Heaters Burning Jet Fuels.
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| #Ambroz-2016 pmid=27321041
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| //Impact of air pollution on oxidative DNA damage and lipid peroxidation in mothers and their newborns.
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| #Balasubramanian-2013 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3402685/
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| //Differential effects of inhalation exposure to PM2.5 on hypothalamic monoamines and corticotrophin releasing hormone in lean and obese rats.
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| </biblio>
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| == License ==
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| Copyright (C) 2012-2016 Etienne Robillard
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| Permission is granted to copy, distribute and/or modify this document
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| Under the terms of the GNU Free Documentation License, Version 1.3
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| or any later version published by the Free Software Foundation;
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| with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts.
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| A copy of the license is included in the section entitled "GNU Free Documentation License".
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| __NOTOC__
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| == See you in space cowboy ==
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| <blockquote>
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| "I am free, no matter what rules surround me. If I find them tolerable, I tolerate them; if I find them too obnoxious, I break them.
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| I am free because I know that I alone am morally responsible for everything I do." -Robert A. Heinlein
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| </blockquote>
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| <blockquote>
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| "The essence of the independent mind lies not in what it thinks, but in how it thinks."
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| ― Christopher Hitchens
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| </blockquote>
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| <blockquote>"Now let us consider another kind of drug – still undiscovered, but probably just around the corner – a drug capable of making people feel happy in situations where they would normally feel miserable. Such a drug would be a blessing, but a blessing fraught with grave political dangers. By making harmless chemical euphoria freely available, a dictator could reconcile an entire population to a state of affairs to which self-respecting human beings ought not to be reconciled. Despots have always found it necessary to supplement force by political or religious propaganda. In this sense the pen is mightier than the sword. But mightier than either the pen or the sword is the pill. In mental hospitals it has been found that chemical restraint is far more effective than strait jackets or psychiatry. The dictatorships of tomorrow will deprive men of their freedom, but will give them in exchange a happiness none the less real, as a subjective experience, for being chemically induced. The pursuit of happiness is one of the traditional rights of man; unfortunately, the achievement of happiness may turn out to be incompatible with another of man's rights – liberty." - Aldous Huxley
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| </blockquote>
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