User:Tkadm30/Notebook/chim trills notebook: Difference between revisions
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1. The biological impacts of aerosolized nanoparticles (ANP) are poorly understood. | 1. The biological impacts of aerosolized nanoparticles (ANP) are poorly understood. | ||
2. The | 2. The nanotoxicity of stratospheric aerosol injection on human health requires further investigations. | ||
3. The differential effects of highly dispersed aerosols (HDA) on the neuroimmune system, lung function, chronic inflammation, and Alzheimer pathogenesis requires additional research. <cite>Gilmour-2004</cite> | 3. The differential effects of highly dispersed aerosols (HDA) on the neuroimmune system, lung function, chronic inflammation, and Alzheimer pathogenesis requires additional research. <cite>Gilmour-2004</cite> | ||
4. | 4. MAC1 is implicated in the dopaminergic-mediated neurotoxicity of aerosolized nanoparticles. <cite>Levesque-2013</cite> | ||
== Differential effects of aerosolized nanoparticles == | == Differential effects of aerosolized nanoparticles == | ||
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** Increase in blood pressure <cite>Balasubramanian-2013</cite> | ** Increase in blood pressure <cite>Balasubramanian-2013</cite> | ||
=== Central nervous system === | === Central nervous system === | ||
* Alzheimer <cite>Jung-2015</cite> | * Alzheimer disease <cite>Jung-2015</cite><cite>Levesque-2013</cite> | ||
* PM2.5 exposure may cause neuroinflammation and oxidative stress. <cite>Lei-2015</cite><cite>Liu-2015</cite><cite>Riva-2011</cite><cite>Levesque-2011</cite> | * Parkinson disease <cite>Levesque-2013</cite> | ||
* PM2.5 exposure may cause chronic neuroinflammation and oxidative stress. <cite>Lei-2015</cite><cite>Liu-2015</cite><cite>Riva-2011</cite><cite>Levesque-2011</cite> | |||
* PM2.5 exposure may induce selective neurotoxicity through glutamatergic signaling and increase NMDA-induced excitotoxicity. <cite>Liu-2015</cite><cite>Morgan-2011</cite> | |||
* Cyclooxygenase-2, interleukin-1beta, and CD14 signaling upregulation. <cite>Solt-2008</cite> | * Cyclooxygenase-2, interleukin-1beta, and CD14 signaling upregulation. <cite>Solt-2008</cite> | ||
* Microglia-mediated dopaminergic neurotoxicity (Reactive microgliosis). <cite>Levesque-2013</cite> | |||
=== Endocrine system === | === Endocrine system === | ||
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* Lung cancer <cite>Hamra-2014</cite> | * Lung cancer <cite>Hamra-2014</cite> | ||
== | == Nanotoxicity of aerosolized nanoparticles == | ||
* | * [[User:Etienne_Robillard/Notebook/chim_trills_notebook/2014/12/14|Notebook]] | ||
== Notes == | == Notes == | ||
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** [http://www.thenakedscientists.com/forum/index.php?topic=68004 Do coal-based jet fuel (JP-900) emit ultrafine particles?] | ** [http://www.thenakedscientists.com/forum/index.php?topic=68004 Do coal-based jet fuel (JP-900) emit ultrafine particles?] | ||
** [http://www.thenakedscientists.com/forum/index.php?topic=67942 Is coal fly ash a synthetic compound?] | ** [http://www.thenakedscientists.com/forum/index.php?topic=67942 Is coal fly ash a synthetic compound?] | ||
** [http://www.thenakedscientists.com/forum/index.php?topic=68555 Is reactive microgliosis a beneficial or harmful process?] | |||
** [http://www.thenakedscientists.com/forum/index.php?topic=67302 Should we ban geoengineering?] | ** [http://www.thenakedscientists.com/forum/index.php?topic=67302 Should we ban geoengineering?] | ||
** [http://www.thenakedscientists.com/forum/index.php?topic=68061 What is the Gulf War syndrome?] | ** [http://www.thenakedscientists.com/forum/index.php?topic=68061 What is the Gulf War syndrome?] | ||
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== Keywords == | == Keywords == | ||
aerosol, bioaerosol, nanoparticles, aluminium oxide, particulate matter, PM2.5, aerosolized jet fuel, gulf war syndrome, chronic neuroinflammation, vapor phase oxidation, hydrocarbons, barium hexaaluminate | aerosol, bioaerosol, nanoparticles, aluminium oxide, particulate matter, PM2.5, aerosolized jet fuel, gulf war syndrome, chronic neuroinflammation, vapor phase oxidation, hydrocarbons, barium hexaaluminate, microglia, MAC1 | ||
== Support this project == | == Support this project == | ||
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#Solt-2008 pmid=18349428 | #Solt-2008 pmid=18349428 | ||
//Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid beta-42 and alpha-synuclein in children and young adults. | //Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid beta-42 and alpha-synuclein in children and young adults. | ||
#Levesque-2013 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660420/ | |||
//The Role of MAC1 in Diesel Exhaust Particle-induced Microglial Activation and Loss of Dopaminergic Neuron Function | |||
</biblio> | </biblio> | ||
Revision as of 05:32, 17 October 2016
Work-in-progress. Please correct any errors found.
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Hypothesis1. The biological impacts of aerosolized nanoparticles (ANP) are poorly understood. 2. The nanotoxicity of stratospheric aerosol injection on human health requires further investigations. 3. The differential effects of highly dispersed aerosols (HDA) on the neuroimmune system, lung function, chronic inflammation, and Alzheimer pathogenesis requires additional research. [1] 4. MAC1 is implicated in the dopaminergic-mediated neurotoxicity of aerosolized nanoparticles. [2] Differential effects of aerosolized nanoparticlesCardiovascular system
Central nervous system
Endocrine systemLymphatic system
Respiratory systemNanotoxicity of aerosolized nanoparticlesNotes
ResourcesKeywordsaerosol, bioaerosol, nanoparticles, aluminium oxide, particulate matter, PM2.5, aerosolized jet fuel, gulf war syndrome, chronic neuroinflammation, vapor phase oxidation, hydrocarbons, barium hexaaluminate, microglia, MAC1 Support this projectThis project is entirely financed by personal donations. To support this project, use the following link to donate money via Paypal: https://paypal.me/EtienneRobillard References
LicenseCopyright (C) 2012-2016 Etienne Robillard Permission is granted to copy, distribute and/or modify this document Under the terms of the GNU Free Documentation License, Version 1.3 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled "GNU Free Documentation License".
See you in space cowboy
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