User:Tkadm30/Notebook/chim trills notebook/Research: Difference between revisions
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===Characterization of the Gulf War syndrome=== | ===Characterization of the Gulf War syndrome=== | ||
The pathology of the Gulf War syndrome (GWS) is not well characterized: The [http://www.ncbi.nlm.nih.gov/pubmed/21329568 immunotoxicity] and [http://www.geoengineeringwatch.org/documents/barron/Nanosized%20Aluminum%20Altered%20Immune%20Function.pdf nanotoxicity] of metal oxides nanoparticles require further research. | The pathology of the Gulf War syndrome (GWS) is not well characterized: The [http://www.ncbi.nlm.nih.gov/pubmed/21329568 immunotoxicity] and [http://www.geoengineeringwatch.org/documents/barron/Nanosized%20Aluminum%20Altered%20Immune%20Function.pdf nanotoxicity] of metal oxides nanoparticles require further research to assert the role of nanomaterials exposure in the pathology of GWS. | ||
Epidemiological evidences of PM2.5 damage to '''immune''' system: | Epidemiological evidences of PM2.5 damage to '''immune''' system: | ||
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Nanotoxicity of metal oxides nanoparticles: | Nanotoxicity of metal oxides nanoparticles: | ||
* Aluminium oxide nanoparticles may induce proinflammatory response and [http://www.ncbi.nlm.nih.gov/pubmed/25875951 oxidative stress]. | * Aluminium oxide nanoparticles may induce proinflammatory response and [http://www.ncbi.nlm.nih.gov/pubmed/25875951 oxidative stress]. | ||
Translocation and internalization of NPs: | |||
* Wireless drug delivery? | |||
* engineered nanoparticles can be developed to enter blood-brain barrier through intracellular transport. | |||
* [https://www.ncbi.nlm.nih.gov/pubmed/23546675 Cellular internalization of quantum dots.] | |||
== Research projects == | == Research projects == | ||
Revision as of 04:49, 7 October 2016
Objectives
1. My initial objective is to understand how metal oxide nanoparticles are a component of low-dose particulate matter (PM2.5) exposure.
2. Aluminium-induced neurotoxicity and chronic neuroinflammation in the microglia are evidences of the translocation of inhaled PM2.5 particulate matter to the brain.
Accumulation of aluminium oxide nanoparticles in the microglia
Glia activation induced by peripheral administration of aluminum oxide nanoparticles in rat brains
Toxicity of metal oxide nanoparticles exposure
- The nanotoxicity of ultrafine particulate matter (PM2.5) in aerosolized nanoparticles is under investigation.
- The chemical clumping behavior of aerosolized nanoparticles require a sophisticated mechanical delivery system.
Characterization of the Gulf War syndrome
The pathology of the Gulf War syndrome (GWS) is not well characterized: The immunotoxicity and nanotoxicity of metal oxides nanoparticles require further research to assert the role of nanomaterials exposure in the pathology of GWS.
Epidemiological evidences of PM2.5 damage to immune system:
- Alteration of cytokines production
- Inflammation
- Oxidative stress (Aluminium oxide)
- Microglial activation?
- Decrease in neurotrophin expression
Nanotoxicity of metal oxides nanoparticles:
- Aluminium oxide nanoparticles may induce proinflammatory response and oxidative stress.
Translocation and internalization of NPs:
- Wireless drug delivery?
- engineered nanoparticles can be developed to enter blood-brain barrier through intracellular transport.
- Cellular internalization of quantum dots.
Research projects
Differential effects of aerosolized nanoparticles on the immune system and microglial cells
- I aim to discover the physiological functions of aerosolized nanoparticles. In summary, I'm interested to learn how metal oxide nanoparticles induces pulmonary diseases (COPD), oxidative stress, and regulation of NADPH activity.
- The differential effects of metal oxide nanoparticles on chronic neuroinflammation and microglial activation (reactive microgliosis) require further research.
Keywords: metal oxides nanoparticles, bioaerosol, drug delivery, CNS, neuroinflammation, microglia
Knowledge is power: Psychology of modern psychochemical warfare.
Clandestine geoengineering activity is poorly understood. The aim of this research project is to understand how cognitive infiltration is used to deter scientific research on chemtrails nanotoxicity.
Keywords: psychology, consciousness, psychochemicals, science, deception, media blackout, cognitive dissonance, disinformation, cognitive infiltration, troll, education, research
Death of evidences
The scientific evidences of clandestine geoengineering activity are ignored by scientists. I'm interested in understanding why.
