User:Tkadm30/Notebook/chim trills notebook/Research: Difference between revisions
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Translocation and internalization of NPs: | Translocation and internalization of NPs: | ||
* [https://www.ncbi.nlm.nih.gov/pubmed/25658858 Synthetic nucleic acid delivery systems] | * [https://www.ncbi.nlm.nih.gov/pubmed/25658858 Synthetic nucleic acid delivery systems] | ||
* Engineered nanoparticles can be developed to enter blood-brain barrier through intracellular ( | * [https://www.ncbi.nlm.nih.gov/pubmed/27429164 Engineered nanoparticles] can be developed to enter blood-brain barrier through intracellular (siRNA) delivery. | ||
* [https://www.ncbi.nlm.nih.gov/pubmed/23546675 Cellular internalization of quantum dots.] | * [https://www.ncbi.nlm.nih.gov/pubmed/23546675 Cellular internalization of quantum dots.] | ||
Revision as of 03:01, 22 October 2016
Research topics
1. My initial objective is to understand how metal oxide nanoparticles are a component of low-dose particulate matter (PM2.5) exposure.
2. Aluminium-induced neurotoxicity and chronic neuroinflammation in the microglia are evidences of the translocation of inhaled PM2.5 particulate matter to the brain.
Accumulation of aluminium oxide nanoparticles in the microglia
Glia activation induced by peripheral administration of aluminum oxide nanoparticles in rat brains
Toxicity of metal oxide nanoparticles exposure
- The nanotoxicity of ultrafine particulate matter (PM2.5) in aerosolized nanoparticles is under investigation.
- The chemical clumping behavior of aerosolized nanoparticles require a sophisticated mechanical delivery system.
- The purpose of spraying water vapor is invalid.
- The synthetic nature of aerosolized nanoparticles require further research.
Characterization of the Gulf War syndrome
The pathology of the Gulf War syndrome (GWS) is not well characterized: The immunotoxicity and nanotoxicity of metal oxides nanoparticles require further research to validate the role of nanomaterials exposure in the pathology of GWS.
Epidemiological evidences of PM2.5 damage to immune system:
- Alteration of cytokines production
- Inflammation
- Oxidative stress (Aluminium oxide)
- Microglial activation?
- Decrease in neurotrophin expression
Nanotoxicity of metal oxides nanoparticles:
- Aluminium oxide nanoparticles may induce proinflammatory response and oxidative stress.
Nanoparticle-based drug delivery
Translocation and internalization of NPs:
- Synthetic nucleic acid delivery systems
- Engineered nanoparticles can be developed to enter blood-brain barrier through intracellular (siRNA) delivery.
- Cellular internalization of quantum dots.
Research projects
Differential effects of aerosolized nanoparticles on the immune system and microglial cells
- I aim to discover the physiological functions of aerosolized nanoparticles. In summary, I'm interested to learn how metal oxide nanoparticles induces pulmonary diseases (COPD), oxidative stress, and regulation of NADPH activity.
- The differential effects of metal oxide nanoparticles on chronic neuroinflammation and microglial activation (reactive microgliosis) require further research.
Keywords: metal oxides nanoparticles, bioaerosol, drug delivery, CNS, neuroinflammation, microglia
Knowledge is power: Psychology of modern psychochemical warfare.
Clandestine geoengineering activity is poorly understood. The aim of this research project is to understand how cognitive infiltration is used to deter scientific research on chemtrails nanotoxicity.
Keywords: psychology, consciousness, psychochemicals, science, deception, media blackout, cognitive dissonance, disinformation, cognitive infiltration, troll, education, research
Death of evidences
The scientific evidences of clandestine geoengineering activity are ignored by scientists. I'm interested in understanding why.