User:Federico Castro M/Projects/VSFH

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
(Data: Estimate the genomic size of LUCA.)
Line 1: Line 1:
This project is about designing an organism that resembles the Last Universal Common Ancestor and whose construction is feasible.  
This project is about designing an organism that resembles the Last Universal Common Ancestor and whose construction is feasible.  
 +
 +
==Replication machinery==
We have to start by:
We have to start by:
* Estimate the genomic size of LUCA.
* Estimate the genomic size of LUCA.
-
Recent estimates sugest that LUCA was complex and probably had more than 600 genes ([http://www.informatics.sussex.ac.uk/users/ctf20/dphil_2005/CSNs/Minimal%20Genome/nrmicro751.pdf Kooning 2003]).
+
Concivably an organism could survive in a controlled environment with a minimal genome of just 113kbp and 151 genes ([http://www.nature.com/msb/journal/v2/n1/full/msb4100090.html Forster 2006]). However, recent estimates sugest that LUCA was complex and probably had more than 600 genes ([http://www.informatics.sussex.ac.uk/users/ctf20/dphil_2005/CSNs/Minimal%20Genome/nrmicro751.pdf Kooning 2003]).
* Check if a RNA genome can sustain such genome size.
* Check if a RNA genome can sustain such genome size.
* Does it had the necesary genetic machinery to support DNA?
* Does it had the necesary genetic machinery to support DNA?

Revision as of 16:01, 10 November 2009

This project is about designing an organism that resembles the Last Universal Common Ancestor and whose construction is feasible.

Replication machinery

We have to start by:

  • Estimate the genomic size of LUCA.

Concivably an organism could survive in a controlled environment with a minimal genome of just 113kbp and 151 genes (Forster 2006). However, recent estimates sugest that LUCA was complex and probably had more than 600 genes (Kooning 2003).

  • Check if a RNA genome can sustain such genome size.
  • Does it had the necesary genetic machinery to support DNA?

Atte (membrillo): Wweww Desde Xicotencatl Tlalpan, translate this Google :)

Personal tools