User:Harald Hentschke
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Contact Info
Harald Hentschke
Section of Experimental Anaesthesiology
Department of Anaesthesiology, University Hospital of Tuebingen
Schaffhausenstr. 113
72072 Tübingen
Germany
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Education
- Year, PhD, Institute
- Year, MS, Institute
- Year, BS, Institute
Research interests
My principal research interest lies in the modulation of cortical and hippocampal networks by classical neuromodulators (acetylcholine) and substances interfering with GABAergic inhibition. Current projects are
- Cholinergic modulation of GABAergic inhibition in neocortex
- Enhancing spillover of GABA to peri- und extrasynaptic GABA(A) receptors – a possible route to anesthesia?
A methodological focus is the development of software tools (mostly written in Matlab) for data analysis and experimental control in the neurosciences. The aim is to produce customized and efficient/automated tools. Projects past and present include
- 'Measures of effect size toolbox' (with Maik Stüttgen, University of Bochum), available at the Matlab Central File Exchange and SourceForge
- time- and frequency domain analysis of multielectrode field potential recordings
- graphical user interface programs for event detection (e.g. spikes, postsynaptic currents) and IPSC fitting
- event-triggered stimulation/feedback control of behavioral setup for awake behaving rodents
Publications
- Goldbeter A and Koshland DE Jr. An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A. 1981 Nov;78(11):6840-4. DOI:10.1073/pnas.78.11.6840 |
- JACOB F and MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318-56. DOI:10.1016/s0022-2836(61)80072-7 |
leave a comment about a paper here
- ISBN:0879697164
