(Difference between revisions)
 Revision as of 00:04, 17 October 2013 (view source) (Autocreate 2013/10/16 Entry for User:Hussein_Alasadi/Notebook/stephens)← Previous diff Revision as of 00:16, 17 October 2013 (view source) (→Entry title)Next diff → Line 6: Line 6: | colspan="2"| | colspan="2"| - ==Entry title== + ==Simulating evolution and then pooled sequencing== - * Insert content here... + + * '''We start with a population of N individuals with a certain SNP distribution $P(M) ~ N(\mu, \Sigma)$.''' + To do this we can use Dick Hudson's MS to lay down neutral variants (but the distribution really does not matter). + + * '''We then evolve the populations for g generations with recombination''' + To do this we can use Kessner's [http://arxiv.org/abs/1310.3234 Forqs]. Forqs allows the user to specify the recombination rate file. Which might be useful in the future. + + * '''Simulate pooled sequencing''' + + + + +

## Revision as of 00:16, 17 October 2013

Analyzing pooled sequenced data with selection Main project page
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## Simulating evolution and then pooled sequencing

• We start with a population of N individuals with a certain SNP distribution $P(M) ~ N(\mu, \Sigma)$.

To do this we can use Dick Hudson's MS to lay down neutral variants (but the distribution really does not matter).

• We then evolve the populations for g generations with recombination

To do this we can use Kessner's Forqs. Forqs allows the user to specify the recombination rate file. Which might be useful in the future.

• Simulate pooled sequencing