- Ian Tay
- Blg 16-760, Engelward Laboratory
- DNA damage and repair
- Cellular responses to chemo-therapeutics
- Long non-coding RNA
I am working with Prof. Bevin Engelward and Dr. Scott Floyd at the Koch Institute to study how tumor cells respond to DNA damaging chemotherapeutic agents and genes that confer cellular resistance to those drugs.
Currently I am working on 2 projects:
1. To design a screen that will allow us to identify genes that can potentially affect cellular resistance to radiotherapy and chemotherapy via modulation of DNA damage and repair kinetics.
2. To study the effects of cell cycle on the evolution and resolution of DNA damage after chemotherapeutic agent treatment.
- Development of a bioartificial hemodialysis device
- Investigating pore formation in endothelial cells by mechanical stimulation
- Non-coding RNAs in early neuronal differentiation