User:Ilya/Yeast/Mating pheromone response pathway/Cdc28

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  • a Ser/Thr kinase
  • Cdc28 is active when T169 is phosphorylated and T18 and Y19 are NOT phosphorylated (SwissProt).

The above statement was made by similarity arguments, though I have not found this statement anywhere in the literature.

  • Ash1 is a potential substrate (restrict switching of mating types to mother cells)
  • CKS1/YBR135W is a subunit of CDC28
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