User:Jacqueline Soegaard

I am a new member of OpenWetWare!

Contact Info

Jacqueline Soegaard (an artistic interpretation)

• Jacqueline Soegaard
• MIT
• Cambridge, MA
• jmsoe@mit.edu
• Email me through OpenWetWare

I work in the 20.109 Lab at MIT. I learned about OpenWetWare from Natalie Kuldell, and I've joined because Student in BE 20.109.

Education

• MIT Class of 2012, Course 20: Biological Engineering

Research interests

# Interest 1: Using genetic and/or protein engineering to improve lipid synthesis pathways in microalgae

Background:

By using available genome sequence information from a variety of algae, as well as known methods of microaglae transformation, we could select a point in the

Sources:

• Genetic Engineering of Algae for Enhanced Biofuel Production

Radakovits R, Jinkerson RE, Darzins A, Posewitz1 MC. Eukar Cell 2010 (9,4):486–501.

This review collects the current research regarding algae biofuels and summarizes the challenges that need to be addressed in order to make algae a viable source of biofuels. Some of the approaches proposed in this paper include: upgrading the direct biosynthesis of lipids, altering lipid characteristics so as to make them a more relevant fuel source, optimizing the conversion of carbohydrates to lipids, and improving photosynthetic efficiency. From this paper, which was just published this month, we gathered that there is great interest in developing algae biofuels as an energy source. As a consequence of this, there is ample opportunity for innovation and genetic optimization. This paper also contains numerous references that can serve as starting points for research ideas and tools.

• Some interesting presentations:

[http://spg.ucsd.edu/algae/pdf/Mayfield_UCSD%20biofuels%201-29.pdf Genetic Engineering of Algae for Biofuel Production]

Engineering Challenges in Algae Energy

• Useful webpages:

UCSD Center for Algae Techology

• Potentially useful articles:

- - -

Useful links

• Introductory tutorial
• OpenWetWare help pages

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Registration/Questionnaire: 20.109 Spring 2010

Last Name

Soegaard

First Name

Jacqueline

Course/Minor

Major: Course 20 (Biological Engineering); Potential Minor: Management Science in Course 15, French

Year of Graduation

2012

Telephone #

787.548.7440

Email

jmsoe@mit.edu

Potentially Relevant Background

Have you taken/are you taking...	Answer yes/no/when
7.05/5.07 (Biochemistry)	No
7.06 (Cell Biology)	No
7.03 (Genetics)	Yes; Spring 2010
7.02 (General Biology Lab)	No
5.310 (General Chemistry Lab)	No

Do you have experience with...	Answer yes/no/type
Cell culture (microbial/mammalian/yeast?)	Yes, mammalian.
Molecular biology (electrophoresis, PCR, etc)	Yes, PCR, electrophoresis, ELISA.

Please briefly describe any previous laboratory experience

I worked at the Broad Institute during a summer genomics course as part of the MIT MITES program. Last semester I UROPed at the Khademhosseini Lab, where I worked on a project which aimed at designing a chip device for detecting cardiotoxicity using a miniaturized ELISA and in-chip cell cultures.

Anything else you would like us to know?

I have NEVER seen such a gorgeous lab before!

Commitment to academic integrity

After you print out this page, please sign your name next to the following statement to indicate your agreement:

I have read and understood the 20.109 statement on collaboration and integrity.

Jing Jing Gong