User:James Chappell: Difference between revisions

From OpenWetWare
Jump to navigationJump to search
mNo edit summary
(73 intermediate revisions by the same user not shown)
Line 1: Line 1:
Department of Biochemistry
<html>
<style type="text/css">
.firstHeading {display: none;}
</style>
</html>


Imperial College London
__NOTOC__


South Kensington, SW7
<div style="padding: 10px; width: 700px; color: #FFFFFF; background-color: #2171B7">
<font face="trebuchet ms" style="color:#FFFFFF" size="6">'''James Chappell'''</font><br>
<br>
</div>
<div style="padding: 10px; width: 700px; color: #FFFFFF; background-color: #2171B7">
</div>
=== Research Interests ===
{| cellspacing="4"
|-valign="top"
|width=40%|
 
I am currently working as a postdoctoral researcher with Prof. Julius Lucks (Lucks Lab) at Cornell University in the School of Chemical and Biomolecular Engineering. I previously obtained a  BSc degree in Biochemistry at Imperial College London, where I continued as a PhD student in Molecular Biosciences under the supervision of Prof. Paul Freemont working at the Imperial College Center for Synthetic Biology and Innovation. My research interests are broadly focused in Synthetic Biology.


London, UK
[[Image: nfig001.jpg|center|500px]]<br clear = "all">
|width=10%|


|width=50%|


Email Address - james.chappell@ic.ac.uk


<!--ROW 2-->
|-valign="top"
|width=60%|


===Publications===


1. S. Meyer, J. Chappell, S. Sankar, R Chew, J. B. Lucks* (2015). Improving fold activation of small transcription activating RNAs (STARs) with rational RNA engineering strategies. Biotechnology and Bioengineering. 36, 154-160.


2. J. Chappell, K. E. Watters, M. K. Takahashi, J. B. Lucks* (2015). A Renaissance in RNA Synthetic Biology: New Mechanisms, Applications and Tools for the Future. Current Opinion in Chemical Biology. 28, 47-56.


3. M. K. Takahashi, C. A. Hayes, J. Chappell, Z. Z. Sun, R. M. Murray, V. Noireaux, J. B. Lucks* (2015). Characterizing and Prototyping Genetic Networks with Cell-Free Transcription-Translation Reactions. Methods. Doi: 10.1016/j.ymeth.2015.05.020.


4. J. Chappell, M. K. Takahashi, J. B. Lucks* (2015). Creating Small Transcription Activating RNAs. Nature Chemical Biology, 11, 214-220.


[[User:James_Chappell/Calibration curve|calibration curve]]
5. M. K. Takahashi, J. Chappell, C. A. Hayes, Z. Z. Sun, J. Kim, V. Singhal, K. J. Spring, S. Al-Khabouri, C. P. Fall, V. Noireaux, R. M. Murray, J. B. Lucks* (2014). Rapidly characterizing the fast dynamics of RNA genetic circuitry with in vitro transcription-translation (TX-TL) reactions. ACS Synthetic Biology, 15, 503-515.


6. J. Chappell, M. K. Takahashi, S. Meyer, D. Loughrey, K. E. Watters, J. B. Lucks* (2013). The Centrality of RNA for Engineering Gene Expression. Biotechnology Journal, 8, 1379-1395.


7. J. Chappell, K. Jensen, P.S. Freemont* (2013). Validation of an entirely in vitro approach for rapid prototyping of DNA regulatory elements for synthetic biology. Nucleic Acids Research, 41, 3471-3481.


[[User:James_Chappell/Weak_Promoter| Weak Promoter]]
8. J. Chappell, P. S. Freemont* (2013). In Vivo and In Vitro Characterization of σ 70 Constitutive Promoters by Real-Time PCR and Fluorescent Measurements. Methods in Molecular Biology – Synthetic Biology, 61-74.
<br>
[[User:James_Chappell/strong_Promoter| Strong Promoter]]
<br>
[[User:James_Chappell/Inducible| Inducible]]


9. J. Chappell, P. S. Freemont* (2013). Synthetic biology – A new generation of biofilm biosensors


10. S. Gulati, V. Rouilly, X. Niu, J. Chappell, R. I. Kitney, J. B. Edel, P. S. Freemont and A. J. deMello (2009). Opportunities for microfluidic technologies in synthetic biology. Journal of The Royal Society Interface, 6, 493-506


===Contact Details===


[[Image: PhotoJim.jpg|left|150px]]<br clear = "all">


James Chappell, <br>
120 Olin Hall, <br>
Chemical and Biomolecular Engineering <br>
Cornell, <br>
NY, USA <br>
<br>
<br>
Email - jchappell105@gmail.com


http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=10334980&ordinalpos=56&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
|}
http://www.clontech.com/images/ctq/JUL06UPD/CR671940_CTQJul06_LC_US.pdf
 
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=321501
 
[[User:James_Chappell/ LuxR | LuxR]]
 
[[User:James_Chappell/ Sandbox| My Sandbox]]

Revision as of 16:55, 16 November 2015

<html> <style type="text/css"> .firstHeading {display: none;} </style> </html>


James Chappell

Research Interests

I am currently working as a postdoctoral researcher with Prof. Julius Lucks (Lucks Lab) at Cornell University in the School of Chemical and Biomolecular Engineering. I previously obtained a BSc degree in Biochemistry at Imperial College London, where I continued as a PhD student in Molecular Biosciences under the supervision of Prof. Paul Freemont working at the Imperial College Center for Synthetic Biology and Innovation. My research interests are broadly focused in Synthetic Biology.



Publications

1. S. Meyer, J. Chappell, S. Sankar, R Chew, J. B. Lucks* (2015). Improving fold activation of small transcription activating RNAs (STARs) with rational RNA engineering strategies. Biotechnology and Bioengineering. 36, 154-160.

2. J. Chappell, K. E. Watters, M. K. Takahashi, J. B. Lucks* (2015). A Renaissance in RNA Synthetic Biology: New Mechanisms, Applications and Tools for the Future. Current Opinion in Chemical Biology. 28, 47-56.

3. M. K. Takahashi, C. A. Hayes, J. Chappell, Z. Z. Sun, R. M. Murray, V. Noireaux, J. B. Lucks* (2015). Characterizing and Prototyping Genetic Networks with Cell-Free Transcription-Translation Reactions. Methods. Doi: 10.1016/j.ymeth.2015.05.020.

4. J. Chappell, M. K. Takahashi, J. B. Lucks* (2015). Creating Small Transcription Activating RNAs. Nature Chemical Biology, 11, 214-220.

5. M. K. Takahashi, J. Chappell, C. A. Hayes, Z. Z. Sun, J. Kim, V. Singhal, K. J. Spring, S. Al-Khabouri, C. P. Fall, V. Noireaux, R. M. Murray, J. B. Lucks* (2014). Rapidly characterizing the fast dynamics of RNA genetic circuitry with in vitro transcription-translation (TX-TL) reactions. ACS Synthetic Biology, 15, 503-515.

6. J. Chappell, M. K. Takahashi, S. Meyer, D. Loughrey, K. E. Watters, J. B. Lucks* (2013). The Centrality of RNA for Engineering Gene Expression. Biotechnology Journal, 8, 1379-1395.

7. J. Chappell, K. Jensen, P.S. Freemont* (2013). Validation of an entirely in vitro approach for rapid prototyping of DNA regulatory elements for synthetic biology. Nucleic Acids Research, 41, 3471-3481.

8. J. Chappell, P. S. Freemont* (2013). In Vivo and In Vitro Characterization of σ 70 Constitutive Promoters by Real-Time PCR and Fluorescent Measurements. Methods in Molecular Biology – Synthetic Biology, 61-74.

9. J. Chappell, P. S. Freemont* (2013). Synthetic biology – A new generation of biofilm biosensors

10. S. Gulati, V. Rouilly, X. Niu, J. Chappell, R. I. Kitney, J. B. Edel, P. S. Freemont and A. J. deMello (2009). Opportunities for microfluidic technologies in synthetic biology. Journal of The Royal Society Interface, 6, 493-506

Contact Details


James Chappell,
120 Olin Hall,
Chemical and Biomolecular Engineering
Cornell,
NY, USA

Email - jchappell105@gmail.com

Retrieved from "https://openwetware.org/mediawiki/index.php?title=User:James_Chappell&oldid=915376"