User:Jayajit Das

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(Lab Alumni)
Current revision (08:22, 3 November 2016) (view source)
(Contact Info)
 
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*'''Jayajit Das'''  
*'''Jayajit Das'''  
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Assistant Professor<br />
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Associate Professor<br />
Battelle Center for Mathematical Medicine<br />
Battelle Center for Mathematical Medicine<br />
The Research Institute at Nationwide Children's Hospital<br />
The Research Institute at Nationwide Children's Hospital<br />
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* 2000      Ph.D. Physics, Raman Research Institute, Bangalore, India
* 2000      Ph.D. Physics, Raman Research Institute, Bangalore, India
* 1996      M.Sc. Physics, Institute of Mathematical Sciences, Chennai (Madras) India
* 1996      M.Sc. Physics, Institute of Mathematical Sciences, Chennai (Madras) India
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* 1994      B.Sc. Physics, Presidency College, Kolkata(Calcutta), India  
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* 1994      B.Sc. Physics, Presidency College, Kolkata(Calcutta), India
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My lab uses theoretical and computational approaches based on statistical physics to uncover basic mechanistic principles underlying our innate and adaptive immune response. Obtaining such mechanistic principles from experimental observations alone is often difficult because the pertinent processes include co-operative dynamic events with many participating components. A further complication that confounds intuition is stochastic fluctuations in these systems with small numbers of molecules. However, by synergistically integrating observations from experiments with transgenic animals, single molecule techniques and imaging studies probing molecular events in live animals with these theoretical and computational approaches we can provide system-level understanding into such complex systems. The mechanistic insight gained from such studies not only will help develop future experiments to unravel basic principles of our immune system, but may also help envision therapeutic strategies for infectious diseases and autoimmune disorders.
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==Research Area==
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The primary focus of our research is uncovering mechanisms and physical principles that underlie host-microbe relationships. My group uses mathematical and computational techniques rooted in engineering, nonlinear dynamics, statistics and physics, in particular, statistical physics. A large number of the projects in my group are carried out in synergistic collaboration with our experimental collaborators. The rest of my research effort is invested in analyzing specific living systems with reduced models for unraveling novel physical principles. The long-term goal of our research endeavor is two-fold: (i) to uncover basic mechanisms to help envision therapeutic strategies for diseases related to our immune system, (ii) to find novel physical principles that underlie host-microbe relations. Our research projects can be broadly classified into three interlinked themes: (1) Lymphocyte signaling and activation. (2) Host-microbe relation in polymicrobial infections (Otitis Media). (3) Physics of single cell and cell populations.
== Lab members ==
== Lab members ==
Sayak Mukherjee (Ph.D Physics, V.Tech) Postdoc <br />
Sayak Mukherjee (Ph.D Physics, V.Tech) Postdoc <br />
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Aleya Dhanji Graduate student, OSU Physics Department <br />
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Vinal Lakhani (PhD Bioinformatics and Computational Biology, UNC Chapel Hill) Postdoc <br />
== Lab Alumni ==
== Lab Alumni ==
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==Selected Publications==
==Selected Publications==
<biblio>
<biblio>
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#Paper1 pmid=23298061
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#Paper1 pmid=26958894
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#Paper2 pmid=23281368
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#Paper2 pmid=26880557
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#Paper3 pmid=22378749
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#Paper3 pmid=26843809
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#Paper4 pmid=20923636
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#Paper4 pmid=26284480
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#Paper5 pmid=20029448
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#Paper5 pmid=25473880
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#Paper6 pmid=19566183
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#Paper6 pmid=25359276
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#Paper7 pmid=19366993
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#Paper7 pmid=24280043
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#Paper8 pmid=19167334
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#Paper8 pmid=24164951
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#Paper9 pmid=19098101
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#Paper9 pmid=24167288
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#Paper10 pmid=18760640
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#Paper10 pmid=24066087
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#Paper11 pmid=18025473
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#Paper11 pmid=23298061
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#Paper12 pmid=17360359
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#Paper12 pmid=23281368
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#Paper13 pmid=17346997
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#Paper13 pmid=22378749
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#Paper14 pmid=20923636
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#Paper15 pmid=20029448
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#Paper16 pmid=19566183
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#Paper17 pmid=19366993
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#Paper18 pmid=19167334
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#Paper19 pmid=19098101
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#Paper20 pmid=18760640
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#Paper21 pmid=18025473
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#Paper22 pmid=17360359
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#Paper23 pmid=17346997
</biblio>
</biblio>
==Useful links==
==Useful links==
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[url=http://www3.clustrmaps.com/user/b259054d][img]http://www3.clustrmaps.com/stats/maps-no_clusters/--openwetware.org-wiki-User-Jayajit_Das-thumb.jpg[/img][/url]
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[http://scholar.google.com/citations?user=iXkBO4MAAAAJ&hl=en&oi=ao  Google_Scholar_Link]
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*More details at http://www.mathmed.org/#Jayajit_Das
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[http://www.clustrmaps.com/map/Openwetware.org Visitor_Map]
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*More details at http://www.nationwidechildrens.org/jayajit-das
==Jobs==
==Jobs==
'''Graduate Student''': Students with a background in Physics, Mathematics, Chemistry, Computer Science or Chemical Engineering are encouraged to apply.
'''Graduate Student''': Students with a background in Physics, Mathematics, Chemistry, Computer Science or Chemical Engineering are encouraged to apply.

Current revision

Contents

Contact Info

  • Jayajit Das

Associate Professor
Battelle Center for Mathematical Medicine
The Research Institute at Nationwide Children's Hospital
Departments of Pediatrics, Physics, Integrated Biomedical Sciences, and Biophysics Graduate Program
The Ohio State University, Columbus, OH 43205

Email: das.70 @ osu.edu; jayajit.das @ nationwidechildrens.org ; jayajit @ gmail.com
Phone: 614-355-5632 (work)
Fax: 614-355-2928
[DasLab]

Education and Professional Experience

  • 2005-2008 Postdoctoral Fellow, Massachusetts Institute of Technology
  • 2002-2005 Postdoctoral Fellow, University of California at Berkeley
  • 2000-2002 Postdoctoral Fellow, Virginia Institute of Polytechnic and State University
  • 2000 Ph.D. Physics, Raman Research Institute, Bangalore, India
  • 1996 M.Sc. Physics, Institute of Mathematical Sciences, Chennai (Madras) India
  • 1994 B.Sc. Physics, Presidency College, Kolkata(Calcutta), India

Research Area

The primary focus of our research is uncovering mechanisms and physical principles that underlie host-microbe relationships. My group uses mathematical and computational techniques rooted in engineering, nonlinear dynamics, statistics and physics, in particular, statistical physics. A large number of the projects in my group are carried out in synergistic collaboration with our experimental collaborators. The rest of my research effort is invested in analyzing specific living systems with reduced models for unraveling novel physical principles. The long-term goal of our research endeavor is two-fold: (i) to uncover basic mechanisms to help envision therapeutic strategies for diseases related to our immune system, (ii) to find novel physical principles that underlie host-microbe relations. Our research projects can be broadly classified into three interlinked themes: (1) Lymphocyte signaling and activation. (2) Host-microbe relation in polymicrobial infections (Otitis Media). (3) Physics of single cell and cell populations.

Lab members

Sayak Mukherjee (Ph.D Physics, V.Tech) Postdoc
Vinal Lakhani (PhD Bioinformatics and Computational Biology, UNC Chapel Hill) Postdoc

Lab Alumni

Michael Dworkin (Math Major, OSU) Undergraduate student
Current Position: Merrimack Pharmaceuticals, Inc

Birra Abdurehman (Math Major, OSU) Undergraduate student
Jagadish Kumar (Postdoc) 2010-2011

Mithila Agnihotri Graduate student, OSU Biophysics Program

Arjun Venkataraman (High School Research Project)

Selected Publications

Error fetching PMID 26958894:
Error fetching PMID 26880557:
Error fetching PMID 26843809:
Error fetching PMID 26284480:
Error fetching PMID 25473880:
Error fetching PMID 25359276:
Error fetching PMID 24280043:
Error fetching PMID 24164951:
Error fetching PMID 24167288:
Error fetching PMID 24066087:
Error fetching PMID 23298061:
Error fetching PMID 23281368:
Error fetching PMID 22378749:
Error fetching PMID 20923636:
Error fetching PMID 20029448:
Error fetching PMID 19566183:
Error fetching PMID 19366993:
Error fetching PMID 19167334:
Error fetching PMID 19098101:
Error fetching PMID 18760640:
Error fetching PMID 18025473:
Error fetching PMID 17360359:
Error fetching PMID 17346997:
  1. Error fetching PMID 26958894: [Paper1]
  2. Error fetching PMID 26880557: [Paper2]
  3. Error fetching PMID 26843809: [Paper3]
  4. Error fetching PMID 26284480: [Paper4]
  5. Error fetching PMID 25473880: [Paper5]
  6. Error fetching PMID 25359276: [Paper6]
  7. Error fetching PMID 24280043: [Paper7]
  8. Error fetching PMID 24164951: [Paper8]
  9. Error fetching PMID 24167288: [Paper9]
  10. Error fetching PMID 24066087: [Paper10]
  11. Error fetching PMID 23298061: [Paper11]
  12. Error fetching PMID 23281368: [Paper12]
  13. Error fetching PMID 22378749: [Paper13]
  14. Error fetching PMID 20923636: [Paper14]
  15. Error fetching PMID 20029448: [Paper15]
  16. Error fetching PMID 19566183: [Paper16]
  17. Error fetching PMID 19366993: [Paper17]
  18. Error fetching PMID 19167334: [Paper18]
  19. Error fetching PMID 19098101: [Paper19]
  20. Error fetching PMID 18760640: [Paper20]
  21. Error fetching PMID 18025473: [Paper21]
  22. Error fetching PMID 17360359: [Paper22]
  23. Error fetching PMID 17346997: [Paper23]
All Medline abstracts: PubMed HubMed

Useful links

Google_Scholar_Link

Visitor_Map

Jobs

Graduate Student: Students with a background in Physics, Mathematics, Chemistry, Computer Science or Chemical Engineering are encouraged to apply.

Personal tools