User:Jayajit Das

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==Selected Publications==
==Selected Publications==
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#Paper1 Das J. ''Activation or Tolerance of Natural Killer Cells is Modulated by Ligand Quality in a Non-Monotonic Manner''. Biophys. J. (2010), accepted for publication.
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#Paper2 pmid=19566183
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#Paper2 pmid=20029448
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#Paper3 pmid=19366993
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#Paper3 pmid=19566183
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#Paper4 pmid=19167334
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#Paper4 pmid=19366993
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#Paper5 pmid=19098101
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#Paper5 pmid=19167334
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#Paper6 pmid=18760640
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#Paper6 pmid=19098101
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#Paper7 pmid=18025473  
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#Paper7 pmid=18760640
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#Paper8 pmid=17360359
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#Paper8 pmid=18025473  
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#Paper9 pmid=17346997
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#Paper10 pmid=17346997
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Revision as of 15:26, 30 July 2010

Contents

Contact Info

  • Jayajit Das

Assistant Professor
Battelle Center for Mathematical Medicine
The Research Institute at Nationwide Children's Hospital
Departments of Pediatrics, Physics, Integrated Biomedical Science and Biophysics Graduate Programs
Ohio State University, Columbus, OH 43205

Email: das.70 @ osu.edu; jayajit.das @ nationwidechildrens.org ; jayajit @ gmail.com
Phone: 614-355-4526 (work)
Fax: 614-355-2928

Education and Professional Experience

  • 2005-2008 Postdoctoral Fellow, Massachusetts Institute of Technology
  • 2002-2005 Postdoctoral Fellow, University of California at Berkeley
  • 2000-2002 Postdoctoral Fellow, Virginia Institute of Polytechnic and State University
  • 2000 Ph.D. Physics, Raman Research Institute, Bangalore, India
  • 1996 M.Sc. Physics, Institute of Mathematical Sciences, Chennai (Madras) India
  • 1994 B.Sc. Physics, Presidency College, Kolkata(Calcutta), India

My lab uses theoretical and computational approaches based on statistical physics to uncover basic mechanistic principles underlying our innate and adaptive immune response. Obtaining such mechanistic principles from experimental observations alone is often difficult because the pertinent processes include co-operative dynamic events with many participating components. A further complication that confounds intuition is stochastic fluctuations in these systems with small numbers of molecules. However, by synergistically integrating observations from experiments with transgenic animals, single molecule techniques and imaging studies probing molecular events in live animals with these theoretical and computational approaches we can provide system-level understanding into such complex systems. The mechanistic insight gained from such studies not only will help develop future experiments to unravel basic principles of our immune system, but may also help envision therapeutic strategies for infectious diseases and autoimmune disorders.

Lab members

Sayak Mukherjee (Ph.D Physics, V.Tech) Postdoc
Michael Dworkin (Math Major, OSU) Undergraduate
Justin Wiser (Math, OSU) Graduate student working for a summer project
Katherine Williams (MBI) Graduate student working on a joint project with Avner Friedman (MBI)
Adam LaChappelle (Metro High School Research Project)

Selected Publications

Error fetching PMID 20029448:
Error fetching PMID 19566183:
Error fetching PMID 19366993:
Error fetching PMID 19167334:
Error fetching PMID 19098101:
Error fetching PMID 18760640:
Error fetching PMID 18025473:
Error fetching PMID 17360359:
Error fetching PMID 17346997:
  1. Das J. Activation or Tolerance of Natural Killer Cells is Modulated by Ligand Quality in a Non-Monotonic Manner. Biophys. J. (2010), accepted for publication. [Paper1]
  2. Error fetching PMID 20029448: [Paper2]
  3. Error fetching PMID 19566183: [Paper3]
  4. Error fetching PMID 19366993: [Paper4]
  5. Error fetching PMID 19167334: [Paper5]
  6. Error fetching PMID 19098101: [Paper6]
  7. Error fetching PMID 18760640: [Paper7]
  8. Error fetching PMID 18025473: [Paper8]
  9. Error fetching PMID 17360359: [Paper9]
  10. Error fetching PMID 17346997: [Paper10]
All Medline abstracts: PubMed HubMed

Useful links

[url=http://www3.clustrmaps.com/user/b259054d][img]--openwetware.org-wiki-User-Jayajit_Das-thumb.jpg[/img][/url]

Jobs

Graduate Student: Students with a background in Physics, Mathematics, Chemistry, Computer Science or Chemical Engineering are encouraged to apply.

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