User:Jayanthi Jayakumar

From OpenWetWare

(Difference between revisions)
Jump to: navigation, search
(Background Information)
(Background Information)
Line 29: Line 29:
=== Background Information ===
=== Background Information ===
Cardiac diseases are one of the most common diseases in the world. This is especially problematic because heart failures are one the leading causes of death [2]. Chronic high blood pressure and heart attacks are widespread disorders that affect a wide range of people. These disorders cause irreparable damages to the heart tissue, eventually leading to heart failure. Unfortunately, the human heart does not have a mechanism to regenerate damaged heart tissues.
Cardiac diseases are one of the most common diseases in the world. This is especially problematic because heart failures are one the leading causes of death [2]. Chronic high blood pressure and heart attacks are widespread disorders that affect a wide range of people. These disorders cause irreparable damages to the heart tissue, eventually leading to heart failure. Unfortunately, the human heart does not have a mechanism to regenerate damaged heart tissues.
-
Researchers in the past have used embryonic stem cells, endothelial progenitor cells and mesenchymal stem cells to
+
Researchers in the past have used embryonic stem cells, endothelial progenitor cells and mesenchymal stem cells to try to regenerate these tissues. However, none of these seem to be as successful as expected.
 +
With the recent discovery of cardiac stem cells, the opportunity to induce regeneration of damaged heart tissue using the body's own cells is promising.
=== Project Overview ===
=== Project Overview ===

Revision as of 22:09, 28 April 2008

I am a new member of OpenWetWare!

Image:Jayanthi.jpeg



Jayanthi Jayakumar

Department of Biological Engineering
631 McCormick Hall
320 Memorial Drive
Cambridge, MA 02139

jayanthi@mit.edu

Hi! This website is for my 20.109 class, Laboratory Fundamentals of Biological Engineering.

Contents

Module 3 Project Proposal (work in progress)

Project Title

Growth of cardiac stem cells and the preservation of their characteristics in vitro.

Background Information

Cardiac diseases are one of the most common diseases in the world. This is especially problematic because heart failures are one the leading causes of death [2]. Chronic high blood pressure and heart attacks are widespread disorders that affect a wide range of people. These disorders cause irreparable damages to the heart tissue, eventually leading to heart failure. Unfortunately, the human heart does not have a mechanism to regenerate damaged heart tissues. Researchers in the past have used embryonic stem cells, endothelial progenitor cells and mesenchymal stem cells to try to regenerate these tissues. However, none of these seem to be as successful as expected. With the recent discovery of cardiac stem cells, the opportunity to induce regeneration of damaged heart tissue using the body's own cells is promising.

Project Overview

Research problem

(Predicted Problems)

  • Isolation of CSCs
  • Optimization of growth conditions
  • Transplation of CSCs in vivo

Details and Methods

Predicted Outcomes

References

Research Interests

  • Cardiac Research
  • Cancer Research

Education

Shaker High School 2006

MIT ~ Biological Engineering 2010

Publications

~Hopefully coming up soon!!!




Useful links

Registration/Questionnaire: 20.109 Spring 2008

Last Name

Jayakumar

First Name

Jayanthi

Preferred name

Jayanthi

Course/Minor

Major: Biological Engineering
Minor: Biology

Year of Graduation

2010

Telephone #

518-301-1834

Email

jayanthi AT mit DOT edu

Have you taken any of these classes?

7.05/5.07 (Biochemistry)
7.06 (Cell Biology)
7.02 (General Biology Lab)
5.310 (General Chemistry Lab)

I am taking 7.05 this semester.

Do you have any experience culturing cells (mammalian, yeast or microbial)?

Yes. I have expereince culturing Bone Marrow Derived Cells and hybridomas.

Do you have any experience in molecular biology (electrophoresis, PCR, etc)?

Yes. I have some experience doing gel electrophoresis.

Please briefly describe any previous laboratory experience

I have been working at the Laboratory for Multiscale Regenerative Technologies for a little more than a year now.
The goal of my project is to target deliver iron oxide nanoparticles for theraputic purposes in cancer treatments.

Anything else you would like us to know?

I absolutely love working in my lab and I am really looking forward to learning a lot from this class.

Personal tools