User:John Cumbers

John Cumbers

NASA Ames Research Center
Mail Stop 239-20, Bldg N239 Rm 373
P.O. Box 1, Moffett Field, CA 94035-0001, USA.
cell +1 (401) 523 8190, office +1 (650) 604-1914, fax +1 (650) 604-1088

Graduate Program in Molecular Biology, Cell Biology, and Biochemistry
Brown University, Box G-W Providence, RI, 02912, USA

John underscore Cumbers at brown dot edu
John dot Cumbers at NASA dot gov

I'm a graduate student in the Cellular Biology, Molecular Biology and Biochemistry Graduate Program at Brown University. Since 2008 I've been working at NASA Ames Research Center in Silicon Valley, California. My research involves synthetic biology, extremophiles and applications of biological engineering to space settlement.

Research Interests

Synthetic biology with applications to space Settlement

Radiation and cold tolerance in cyanobacteria

Standards and part characterization for synthetic biology

Mechanisms of aging

Education

Ph.D student, Brown University 2005-present
M.Sc, University of Edinburgh, 2005 (Bioinformatics)
B.Sc, University of Hull, 2004 (Computer Science with Information Engineering)

Publications

Measuring the activity of BioBrick promoters using an in vivo reference standard
Journal of Biological Engineering, 2009 March 20;3:4
Jason R Kelly, Adam J Rubin, Caroline M Ajo-Franklin, John Cumbers, Michael J. Czar, Kim de Mora, Aaron L Glieberman, Dileep D Monie, Drew Endy
URL PDF reprint

Drosophila Germ Line Modulation of Insulin Signaling and Lifespan Flatt, T., Min, K., D’Alterio, C., Villa-Cuesta, E., Cumbers, J., Lehmann,R., Jones, D.L., Tatar,M., PNAS (in press 2008).

Progress toward construction and modelling of a tri-stable toggle switch in E. coli Lohmueller, J.; Neretti, N.; Hickey, B.; Kaka, A.; Gao, A.; Lemon, J.; Lattanzi, V.; Goldstein, P.; Tam, L.K.; Schmidt, M.; Brodsky, A.S.; Haberstroh, K.; Morgan, J.; Palmore, T.; Wessel, G.; Jaklenec, A.; Urabe, H.; Gagnon, J.; Cumbers, J. IET Synthetic Biology, 2007.

Annual Report for the American Federation for Aging Research. 2006 (Cover art, Insulin vesicles in the fruit fly brain, confocal microscopy, Left)

Conference posters and abstracts

BioSysBio 2007: Conference in Systems Biology, Bioinformatics and Synthetic Biology Manchester, UK. 11-13 January 2007. Abstracts. Editor. BMC Syst Biol. 2007;1 Suppl 1:P1-S15.

Constructing a insulin sensitive cell, second international conference on synthetic biology (2.0). Poster UC Berkeley. 2006

Computational Analysis of Insulin in the Ageing Fruit Fly Cumbers, J., and Armstrong, J.D. Abstract from BioSysBio 2005: Bioinformatics and Systems Biology Conference, Edinburgh, UK, BMC Bioinformatics 2005, 6(Suppl 3):P9 doi:10.1186/1471-2105-6-S3-P9

BioSysBio: Bioinformatics and Systems Biology Conference. Edinburgh, UK. 14-15 July 2005. Abstracts. BMC Bioinformatics. 2005 Sep 9;6 Suppl 3:P21-29, S1-15. PMID: 16219110 [PubMed - indexed for MEDLINE]