User:Johnsy/Lipoprotein Modelling/References

Books & Papers

1. ISBN:071673706X
2. ISBN:047119350X

Lipoproteins

3. Brown MS and Goldstein JL. Receptor-mediated endocytosis: insights from the lipoprotein receptor system. Proc Natl Acad Sci U S A. 1979 Jul;76(7):3330-7. DOI:10.1073/pnas.76.7.3330 |
4. Brown MS and Goldstein JL. A receptor-mediated pathway for cholesterol homeostasis. Science. 1986 Apr 4;232(4746):34-47. DOI:10.1126/science.3513311 |
5. Goldstein JL and Brown MS. The low-density lipoprotein pathway and its relation to atherosclerosis. Annu Rev Biochem. 1977;46:897-930. DOI:10.1146/annurev.bi.46.070177.004341 |
6. Goldstein JL and Brown MS. Regulation of the mevalonate pathway. Nature. 1990 Feb 1;343(6257):425-30. DOI:10.1038/343425a0 |
7. Hussain MM. A proposed model for the assembly of chylomicrons. Atherosclerosis. 2000 Jan;148(1):1-15. DOI:10.1016/s0021-9150(99)00397-4 |
8. Willnow TE, Nykjaer A, and Herz J. Lipoprotein receptors: new roles for ancient proteins. Nat Cell Biol. 1999 Oct;1(6):E157-62. DOI:10.1038/14109 |

HMG CoA Reductase

9. Bischoff KM and Rodwell VW. Biosynthesis and characterization of (S)-and (R)-3-hydroxy-3-methylglutaryl coenzyme A. Biochem Med Metab Biol. 1992 Oct;48(2):149-58. DOI:10.1016/0885-4505(92)90060-c |
10. Endo A. The discovery and development of HMG-CoA reductase inhibitors. J Lipid Res. 1992 Nov;33(11):1569-82.
11. Istvan ES, Palnitkar M, Buchanan SK, and Deisenhofer J. Crystal structure of the catalytic portion of human HMG-CoA reductase: insights into regulation of activity and catalysis. EMBO J. 2000 Mar 1;19(5):819-30. DOI:10.1093/emboj/19.5.819 |
12. Istvan ES and Deisenhofer J. Structural mechanism for statin inhibition of HMG-CoA reductase. Science. 2001 May 11;292(5519):1160-4. DOI:10.1126/science.1059344 |
13. McGee TP, Cheng HH, Kumagai H, Omura S, and Simoni RD. Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis. J Biol Chem. 1996 Oct 11;271(41):25630-8. DOI:10.1074/jbc.271.41.25630 |
14. Smythe CD, Greenall M, and Kealey T. The activity of HMG-CoA reductase and acetyl-CoA carboxylase in human apocrine sweat glands, sebaceous glands, and hair follicles is regulated by phosphorylation and by exogenous cholesterol. J Invest Dermatol. 1998 Jul;111(1):139-48. DOI:10.1046/j.1523-1747.1998.00246.x |

SREBP Pathway

15. Brown MS and Goldstein JL. The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell. 1997 May 2;89(3):331-40. DOI:10.1016/s0092-8674(00)80213-5 |

Mathematical Models

16. August E, Parker KH, and Barahona M. A dynamical model of lipoprotein metabolism. Bull Math Biol. 2007 May;69(4):1233-54. DOI:10.1007/s11538-006-9132-6 |
17. Barrett PH and Watts GF. Kinetic studies of lipoprotein metabolism in the metabolic syndrome including effects of nutritional interventions. Curr Opin Lipidol. 2003 Feb;14(1):61-8. DOI:10.1097/00041433-200302000-00011 |
18. Shorten PR and Upreti GC. A mathematical model of fatty acid metabolism and VLDL assembly in human liver. Biochim Biophys Acta. 2005 Sep 15;1736(2):94-108. DOI:10.1016/j.bbalip.2005.07.007 |

Other Books and Sources

1. August E. 2004. A Dynamical System is Biology: Lipoprotein Metabolism, MRes Biomolecular Science Thesis.
2. Brown M & Goldstein J, Receptor-mediated endocytosis: Insights from the lipoprotein receptor system, Proc. Nat. Acad. Sci., 76, 3330-3337 (1979)
3. Brown M & Goldstein J, A Receptor Mediated Pathway for Cholesterol Homeostasis, Nobel Prize Lecture, 9 December 1985
4. Cooper K. 2006 Dynamical Modelling of Lipoprotein Metabolism, MSc Bioinformatics Thesis.
5. Feher, M. 1997, Lipids and Lipid Disorders, 2nd edn, Mosby-Wolfe, London.
6. GeneNetWorks Model of Cholesterol Biosynthesis Regulation
7. Panovska J, et al. 2006. Mathematical Models of Hepatic Lipoprotein Metabolism. 5th Mathematics in Medicine Study Group, Oxford University
8. Ratushny A, et al. Mathematical Model of Cholesterol Biosynthesis Regulation in the Cell. Institute of Cytology and Genetics SB RAS, Russia
9. Brown & Goldstein 1977 The Low Density Lipoprotein Pathway and Its Relation to Atherosclerosis
10. iGEM Mathematical Modelling Page

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