Karen J. Liu * King's College London * Department of Craniofacial Development Floor 27, Guy's Tower London Bridge London, UK SE1 9RT * karen.liu<at>kcl.ac.uk
- 2003, PhD, University of California, Berkeley
- 1992, BA, Columbia College, Columbia University
We are adapting new methods to alter protein function in developmental studies; the specific biological problem we are interested in is the formation of the neural crest and its derivatives, including early patterning of the neurectoderm and later development of the craniofacial skeleton.
1. Liu KJ*, Arron JA*, Stankunas K, Crabtree, G, Longaker MT. Chemical rescue of cleft palate and midline defects in conditional GSK-3β mice. Nature 2007 Mar 1;446(7131):79-82. Epub 2007 Feb 11.
2. Liu KJ, Gestwicki, JE and Crabtree GR. “Bringing small molecule regulation of protein activity to developmental systems”, chapter in Analysis of Growth Factor Signaling in Embryos. Editors: Malcolm Whitman and Amy Sater. For Methods in Signal Transduction, CRC Press. 2006.
3. Liu KJ and Harland RM. Inhibition of neurogenesis by SRp38, a NeuroD-regulated RNA binding protein. Development 2005 April; 132(7):1511-23. Epub 2005 Feb 23.
4. Liu KJ and Harland RM. Cloning and characterization of Xenopus Id4 reveals differing roles for Id genes. Developmental Biology 2003 Dec 15; 264(2):339-51.
5. Grammer TC*, Liu KJ*, Mariani FV, Harland RM. Use of large-scale expression cloning screens in the Xenopus laevis tadpole to identify gene function. Developmental Biology 2000 Dec 15;228(2):197-210.