User:Kate Thodey: Difference between revisions
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==Research interests== | ==Research interests== | ||
Many drugs are still produced the traditional way; by extraction from medicinal plants. In many cases the alternative chemical syntheses of such compounds are low-yielding due to the complex nature of these biological molecules. In the Smolke laboratory we are interested in using new synthetic biology approaches to biosynthesize a class of drug molecules which are currently produced by extraction from opium poppies, namely the benzylisoquinoline alkaloids which include the powerful analgesics codeine and morphine. As a | Many drugs are still produced the traditional way; by extraction from medicinal plants. In many cases the alternative chemical syntheses of such compounds are low-yielding due to the complex nature of these biological molecules. In the Smolke laboratory we are interested in using new synthetic biology approaches to biosynthesize a class of drug molecules which are currently produced by extraction from opium poppies, namely the benzylisoquinoline alkaloids which include the powerful analgesics codeine and morphine. As a postdoc working together with members of the laboratory, my research focuses on metabolically engineering yeast to produce opiates and other high-value alkaloids. | ||
==Publications== | ==Publications== | ||
Revision as of 18:39, 12 August 2012
Contact Info Kate Thodey Education
Research interestsMany drugs are still produced the traditional way; by extraction from medicinal plants. In many cases the alternative chemical syntheses of such compounds are low-yielding due to the complex nature of these biological molecules. In the Smolke laboratory we are interested in using new synthetic biology approaches to biosynthesize a class of drug molecules which are currently produced by extraction from opium poppies, namely the benzylisoquinoline alkaloids which include the powerful analgesics codeine and morphine. As a postdoc working together with members of the laboratory, my research focuses on metabolically engineering yeast to produce opiates and other high-value alkaloids. Publications
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