User:Katpak

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Current revision (04:39, 27 February 2010) (view source)
 
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<font size="4">Ekaterina (Kat) Pak</font size>
<font size="4">Ekaterina (Kat) Pak</font size>
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<font size="2">Department of Biological Engineering<br>
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<font size="2">Ph.D. Candidate, Biological and Biomedical Sciences, Harvard University<br>
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MIT<br>
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Cambridge, MA<br>
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[mailto:katpak@mit.edu katpak@mit.edu]
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<font size="2">B.S., Biological Engineering, MIT 2009<br>
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[mailto:katpak@fas.harvard.edu katpak@fas.harvard.edu]
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</font size>
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== Education==
 
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<blockquote>Biological Engineering <br>
 
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MIT, Class of 2009
 
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</blockquote>
 
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== Lab Experience==
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== Research Experience==
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'''MIT Department of Biological Engineering '''
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Cambridge, MA
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Faculty Advisor: Bevin Engelward, direct advisor Dr. Werner Olipitz
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'''Novartis Institutes for Biomedical Research '''<Br>              
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Cambridge, MA<Br>
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Examined the effects of radiation on homologous recombination in mouse pancreata. Working with the fluorescent yellow direct repeat mouse model, I used in situ imaging and flow cytometry to determine the level of induced HR in mouse pancreata as a result of exposure to varying levels of radiation. Publication is pending for the upcoming year on this work. I also recently began work on measuring T cell activation and response to radiation. I will be involved with quantifying cytokine levels in irradiated mice as well as histological comparisons of the mouse gastrointestinal system. I was also responsible for upkeep of the mouse colony and assisted on several other projects in the lab. (January 2008-Present)
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NIBR Summer Internship Program, Cardiovascular and Metabolic Diseases<Br>
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(June 2009-August 2009)
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'''California Institute of Technology '''
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'''MIT Department of Biological Engineering '''<Br>          
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Cambridge, MA<Br>
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Pasadena, CA
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Undergraduate Research<Br>
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Faculty Advisor: Dr. Bevin Engelward, direct advisor Dr. Werner Olipitz <Br>
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(January 2008-January 2009)
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Faculty Advisor: Christina Smolke
 
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Designed and characterized regulatory RNA elements for controlled gene expression. This work was part of a larger project which was entered into the International Genetically Engineered Machines Competition at MIT (iGEM) in fall of 2007. The goal of the project was to regulate the lysis/lysogeny switch in lambda phage upon infection of E. coli. With the help of RNAstructure and VectorNTI software, I designed thirteen interacting RNA elements that would control expression of life cycle genes in lambda phage and measured their interaction with flow cytometry (http://openwetware.org/wiki/IGEM:Caltech/2007/Project/Riboregulator). My research was funded by the Amgen Scholars program. (June 2007-August 2007)
 
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'''California Institute of Technology '''<Br>                        
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Pasadena, CA<Br>
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Amgen Scholars Program<Br>
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Faculty Advisor: Dr. Christina Smolke<Br>
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http://openwetware.org/wiki/IGEM:Caltech/2007/Project/Riboregulator <Br>
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(June 2007-August 2007)
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'''MIT Media Lab '''
 
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Cambridge, MA
 
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Faculty Advisor: Dr. Peter Carr
 
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Assisted in testing proteins for error correction in DNA synthesis. The goal of the project was to make DNA synthesis faster and more efficient. I was responsible for expression of an engineered protein which would detect and correct errors in DNA synthesis. The bulk of my work involved protein expression and solubilization. (January 2006-June 2007)
 
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'''MIT Media Lab '''<Br>        
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Cambridge, MA <Br>
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Undergraduate Research <Br>
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Faculty Advisor: Dr. Peter Carr <Br>
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(January 2006-June 2007)
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'''Public Health Research Institute'''
 
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Newark, NJ
 
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Advisor: Dr. Dan-Oscar Antson
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'''Public Health Research Institute'''<Br>        
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Newark, NJ<Br>
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Assisted in developing a diagnostic assay to detect pathogenic species in humans using fluorescent hybridization probes called molecular beacons. My responsibilities were to quantify levels of beacon-target interactions using real-time PCR. (August 2004-August 2005)
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Internship<Br>
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(August 2004-August 2005)

Current revision


Ekaterina (Kat) Pak

Ph.D. Candidate, Biological and Biomedical Sciences, Harvard University

B.S., Biological Engineering, MIT 2009


katpak@fas.harvard.edu


Research Experience

Novartis Institutes for Biomedical Research
Cambridge, MA
NIBR Summer Internship Program, Cardiovascular and Metabolic Diseases
(June 2009-August 2009)


MIT Department of Biological Engineering
Cambridge, MA
Undergraduate Research
Faculty Advisor: Dr. Bevin Engelward, direct advisor Dr. Werner Olipitz
(January 2008-January 2009)


California Institute of Technology
Pasadena, CA
Amgen Scholars Program
Faculty Advisor: Dr. Christina Smolke
http://openwetware.org/wiki/IGEM:Caltech/2007/Project/Riboregulator
(June 2007-August 2007)


MIT Media Lab
Cambridge, MA
Undergraduate Research
Faculty Advisor: Dr. Peter Carr
(January 2006-June 2007)


Public Health Research Institute
Newark, NJ
Internship
(August 2004-August 2005)

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