User:Lance Martin: Difference between revisions
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**Bi-stable networks | **Bi-stable networks | ||
== | ==Design of engineered biological memory & logic== | ||
[[Image:Process.jpg|thumb|right|Decision tree]] | |||
===Basic construction / design principles=== | |||
*Summary of reviews by | |||
**Voight | |||
**Endy | |||
**Arkin | |||
[[Media:Principles.ppt]] | |||
===Computational modeling=== | |||
*Review of | |||
**Collins toggle switch | |||
**Elowitz repressilator | |||
[[Media:Modeling.ppt]] | |||
*Review of | |||
==Publications== | ==Publications== | ||
Revision as of 14:37, 23 March 2009
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Electronic memory & logic devices
Devices
- Transistors
- Logic gates
- Latches
- D-type flip-flops
- JK flip-flops
Summary presentation
Media:Electronic_Memory_&_Logic_Devices.ppt
Electronic counters & system architecture
Architectures
- Cascade
- Asynchronous
- Synchronous
Summary presentation
Native biological memory & logic
Basic requirements
- Reliably holds state
- Controllable state change
- Many additional application-specific requirements
Systems
- Recombination
- Types of enzymes
- Kinetic modeling recombinase mechanism
- DNA methylation
- Others?
- Feedback loops
- Bi-stable networks
Design of engineered biological memory & logic
Basic construction / design principles
- Summary of reviews by
- Voight
- Endy
- Arkin
Computational modeling
- Review of
- Collins toggle switch
- Elowitz repressilator
- Review of
Publications
- Goldbeter A and Koshland DE Jr. An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A. 1981 Nov;78(11):6840-4. DOI:10.1073/pnas.78.11.6840 |
- JACOB F and MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318-56. DOI:10.1016/s0022-2836(61)80072-7 |
leave a comment about a paper here
- ISBN:0879697164
