User:Lily Wang: Difference between revisions
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Revision as of 07:28, 27 September 2008
I am a new member of OpenWetWare!
Contact Info
- Lily Wang
- Columbia University
- 1130 St. Nicholas Ave.
- ICRC 602
- New York, NY 10032 USA
- Email me through OpenWetWare
I work in the Gautier Lab at Columbia University. I learned about OpenWetWare from the Hoatlin Lab, and I've joined in order to contribute to the Gautier Lab site.
Education
- MD-PhD Student at Columbia University
- 2002, BS Biophysics, Brown University
Current Research Topics
Laboratory of Jean Gautier, Columbia University, 2005-present
- I am studying the role of Fanconi anemia (FA) proteins in DNA replication and repair. I have been studying the molecular requirements for the recruitment of FA proteins to chromatin during unperturbed DNA replication. I have also been examining the role of FA proteins in the replication restart and DNA repair.
Previous Research Topics
Laboratory of Giovanni Romeo, Hospital of Bologna, Italy, 2002-2003
- Using RET tyrosine kinase mutants found Hirschsprung's disease and cancer predisposition syndromes, we studies the role of RET in enteric aganglionosis and caspase activation.
Sedivy Lab, Brown University, 2000-2002
- Using the Shokat method, we engineered Raf-1 mutants with a mutated ATP-binding pocket that preferentially used orthogonal ATP analogs. Using these mutants, we investigated the downstream substrates of Raf-1.
Publications
- Wang LC, Stone S, Hoatlin ME, and Gautier J. Fanconi anemia proteins stabilize replication forks. DNA Repair (Amst). 2008 Dec 1;7(12):1973-81. DOI:10.1016/j.dnarep.2008.08.005 |
- Hindley AD, Park S, Wang L, Shah K, Wang Y, Hu X, Shokat KM, Kolch W, Sedivy JM, and Yeung KC. Engineering the serine/threonine protein kinase Raf-1 to utilise an orthogonal analogue of ATP substituted at the N6 position. FEBS Lett. 2004 Jan 2;556(1-3):26-34. DOI:10.1016/s0014-5793(03)01352-8 |
