User:Lily Wang: Difference between revisions

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*[[Special:Emailuser/Lily Wang|Email me through OpenWetWare]]
*[[Special:Emailuser/Lily Wang|Email me through OpenWetWare]]


I work in the [http://gautier.openwetware.org Gautier Lab] at [http://www.columbia.edu Columbia University].  I learned about [[OpenWetWare]] from the [http://openwetware.org/wiki/Hoatlin_Lab Hoatlin Lab], and I've joined in order to contribute to the Gautier Lab site.
I created this page when I worked in the [http://gautier.openwetware.org Gautier Lab] at [http://www.columbia.edu Columbia University].  I learned about [[OpenWetWare]] from the [http://openwetware.org/wiki/Hoatlin_Lab Hoatlin Lab], and I've joined in order to contribute to the Gautier Lab site.


==Education==
==Education==

Revision as of 10:57, 15 January 2011

I am a new member of OpenWetWare!

Contact Info

Lily Wang

I created this page when I worked in the Gautier Lab at Columbia University. I learned about OpenWetWare from the Hoatlin Lab, and I've joined in order to contribute to the Gautier Lab site.

Education

  • MD-PhD Student at Columbia University
  • 2002, BS Biophysics, Brown University

Current Research Topics

Laboratory of Jean Gautier, Columbia University, 2005-present

  • I am studying the role of Fanconi anemia (FA) proteins in DNA replication and repair. I have been studying the molecular requirements for the recruitment of FA proteins to chromatin during unperturbed DNA replication. I have also been examining the role of FA proteins in the replication restart and DNA repair.

Previous Research Topics

Laboratory of Giovanni Romeo, Hospital of Bologna, Italy, 2002-2003

  • Using RET tyrosine kinase mutants found Hirschsprung's disease and cancer predisposition syndromes, we studies the role of RET in enteric aganglionosis and caspase activation.

Sedivy Lab, Brown University, 2000-2002

  • Using the Shokat method, we engineered Raf-1 mutants with a mutated ATP-binding pocket that preferentially used orthogonal ATP analogs. Using these mutants, we investigated the downstream substrates of Raf-1.


Publications

  1. Wang LC, Stone S, Hoatlin ME, and Gautier J. Fanconi anemia proteins stabilize replication forks. DNA Repair (Amst). 2008 Dec 1;7(12):1973-81. DOI:10.1016/j.dnarep.2008.08.005 | PubMed ID:18786657 | HubMed [Paper2]
  2. Hindley AD, Park S, Wang L, Shah K, Wang Y, Hu X, Shokat KM, Kolch W, Sedivy JM, and Yeung KC. Engineering the serine/threonine protein kinase Raf-1 to utilise an orthogonal analogue of ATP substituted at the N6 position. FEBS Lett. 2004 Jan 2;556(1-3):26-34. DOI:10.1016/s0014-5793(03)01352-8 | PubMed ID:14706820 | HubMed [Paper1]

All Medline abstracts: PubMed | HubMed

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