User:Liuzhec

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Project Overview

  • Our goal is to design and implement molecular containers, which can be dynamically opened and closed by an external stimulus.
  • The containers will be implemented as DNA nanostructures, which afford a significant degree of positional control and chemical versatility.
  • As an initial proof-of-concept, we plan to use our DNA containers to demonstrate controllable activation ("delivery") of anti-thrombin aptamers.
  • We expect that molecular containers could have several interesting scientific and clinical applications, such as
    • Drug and gene delivery
    • Bio-marker scavenging (early detection of biomarkers)
    • Directed evolution (compartmentalized selections)
    • Using multiplexing for combinatorial chemical synthesis
    • Capture and stabilization of multiprotein complexes
    • Protein folding (chaperones)
    • Cell sorting

==Working Team Members== edit

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Welcome to Harvard's 2006 iGEM team wiki! Please click on the project of interest for up to date information and current progress.



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DNA Nanostructures
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Harvard 2006 iGem team.  Back row (L-R): Lewis, Katie, Tiffany, Valerie, Zhipeng, Matt.  Front row (L-R): Hetmann, Jeffrey, David, Perry.  And yes, that is the back end of a bronze rhinoceros.
Harvard 2006 iGem team.

Back row (L-R): Lewis, Katie, Tiffany, Valerie, Zhipeng, Matt.
Front row (L-R): Hetmann, Jeffrey, David, Perry.

And yes, that is the back end of a bronze rhinoceros.

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A thanks goes to MIT's team page for our page formatting.

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