User:Margarida Gama-Carvalho
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Contact Info
- Margarida Gama-Carvalho
- Assistant Professor, Faculty of Medicine, University of Lisbon
- BioFIG - Center for Functional and Integrative Genomics, Faculty of Sciences
- Faculdade de Ciências de Lisboa, Campo Grande, Edifício C8, Sala 1.78
- 1749-016 Lisboa, Portugal
- Email me through OpenWetWare
Education
- 2003, PhD in Biomedical Sciences/Cell and Molecular Biology, Faculty of Medicine, University of Lisbon
- 2000, MS in Cell and Molecular Biology, Faculty of Medicine, University of Lisbon
- 1994, BS in Biology/Zoology, Faculty of Sciences, University of Lisbon
Research interests
- Post-transcriptional control of gene expression by RNA binding proteins and microRNAs
- Development of therapeutical applications
- Bioinformatics
- Systems and synthetic biology
Publications
Papers
- Gama-Carvalho M, Barbosa-Morais NL, Brodsky AS, Silver PA, and Carmo-Fonseca M. Genome-wide identification of functionally distinct subsets of cellular mRNAs associated with two nucleocytoplasmic-shuttling mammalian splicing factors. Genome Biol. 2006;7(11):R113. DOI:10.1186/gb-2006-7-11-r113 |
- Lindberg A, Gama-Carvalho M, Carmo-Fonseca M, and Kreivi JP. A single RNA recognition motif in splicing factor ASF/SF2 directs it to nuclear sites of adenovirus transcription. J Gen Virol. 2004 Mar;85(Pt 3):603-608. DOI:10.1099/vir.0.19722-0 |
- Gama-Carvalho M, Condado I, and Carmo-Fonseca M. Regulation of adenovirus alternative RNA splicing correlates with a reorganization of splicing factors in the nucleus. Exp Cell Res. 2003 Sep 10;289(1):77-85. DOI:10.1016/s0014-4827(03)00251-9 |
- Gama-Carvalho M and Carmo-Fonseca M. The rules and roles of nucleocytoplasmic shuttling proteins. FEBS Lett. 2001 Jun 8;498(2-3):157-63. DOI:10.1016/s0014-5793(01)02487-5 |
- Gama-Carvalho M, Carvalho MP, Kehlenbach A, Valcarcel J, and Carmo-Fonseca M. Nucleocytoplasmic shuttling of heterodimeric splicing factor U2AF. J Biol Chem. 2001 Apr 20;276(16):13104-12. DOI:10.1074/jbc.M008759200 |
- Gama-Carvalho M, Krauss RD, Chiang L, Valcárcel J, Green MR, and Carmo-Fonseca M. Targeting of U2AF65 to sites of active splicing in the nucleus. J Cell Biol. 1997 Jun 2;137(5):975-87. DOI:10.1083/jcb.137.5.975 |
Book Chapters
Gama-Carvalho M., and Carmo-Fonseca, M. (2006). Heterokaryon assays. In "Cell Biology – a Laboratory Handbook", ed. Julio Celis, Academic Press, London, UK.
Gama-Carvalho M., and Carmo-Fonseca, M. (2007). Tráfego de RNA e patogénese. In “O Mundo do RNA: Novos desafios e Perspectivas Futuras”, ed. Cecília M. Arraiano e Arsénio M. Fialho, Lidel, Lisboa, Portugal.
External links
http://openwetware.org/wiki/Gama
http://biofig.fc.ul.pt/
http://www.fm.ul.pt
