User:Maria Clara T Astolfi

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I am a new member of OpenWetWare!

Contact Info

Maria Clara T Astolfi (an artistic interpretation)
  • Maria Clara T Astolfi
  • Federal University of Amazonas
  • Synthetic Biology Hub of Amazonas
  • Multidisciplinary Support Centre
  • Manaus, Amazonas - Brazil

I work in the Your Lab at XYZ University. I learned about OpenWetWare from iGEM competition, and I've joined because We founded the Synthetic Biology Hub of Amazonas - Brazil in 2012. I'm an instructor of our iGEM team, bringing up new SynBio students, highlighting BioBricks Foundation philosophy and goals, building new genetic circuits aiming to contribute to the SynBio community and remove barriers in the way of its advancement. We constructed several standards BioBricks for mercury bioremediation and novel promoters for its improvement. Our hub has also worked building a new logic gate to construct promoters standardizing different sigma factors, operators, -35, -10, extended -10, discriminator and much more sequences. Now we are working to build a standard BioBrick vector for CRISPR/Cas9 genome editing in E. coli, the CRISPeasy. I would love to share our results and what we have done since 2012..

Education

  • Year, PhD, Institute
  • Year, MS, Institute
  • Year, BS, Institute

Research interests

  1. Interest 1
  2. Interest 2
  3. Interest 3

Publications

  1. Goldbeter A and Koshland DE Jr. An amplified sensitivity arising from covalent modification in biological systems. Proc Natl Acad Sci U S A. 1981 Nov;78(11):6840-4. DOI:10.1073/pnas.78.11.6840 | PubMed ID:6947258 | HubMed [Paper1]
  2. JACOB F and MONOD J. Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol. 1961 Jun;3:318-56. DOI:10.1016/s0022-2836(61)80072-7 | PubMed ID:13718526 | HubMed [Paper2]

    leave a comment about a paper here

  3. ISBN:0879697164 [Book1]

All Medline abstracts: PubMed | HubMed

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