User:Matthew A. Jones: Difference between revisions
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[[Image:Tahoe_pic.jpg|thumb|right|Matt Jones]] | |||
==Contact Info== | ==Contact Info== | ||
Harmer Lab, | |||
1002 Life Sciences Addition, | |||
UC Davis, | UC Davis, | ||
One Shields Avenue, | |||
Davis, CA 95616 | |||
majones'''''at'''''ucdavis'''''dot'''''edu | |||
<br> | |||
==Research interests== | |||
<!-- Feel free to add brief descriptions to your research interests as well --> | |||
The circadian clock acts to optimise the cellular behaviour of an organism so that it corresponds with the predictable environmental variation induced by the diurnal cycle. Whilst extensive genetic analyses have identified multiple genes involved in the plant circadian clock the precise mechanism by which these factors interact remains unclear. My current work involves characterisation of additional components of the plant circadian clock which will provide further insight into the workings of the central oscillator. | |||
<br> | |||
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|align="right"|[[Image:ArabClock.jpg|center]] | |||
<small>Some of the feedback loops that form the ''Arabidopsis'' circadian clock. See [http://www.springerlink.com/content/u30561q53l770734/?p=0b3372095be747bc83c7b13cd46fc8c3&pi=0] for more detail</small> | |||
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<br> | |||
==Education== | ==Education== | ||
<!--Include info about your educational background--> | <!--Include info about your educational background--> | ||
* 2007, PhD, [http://www.gla.ac.uk/ | * 2004-2007, PhD, [http://www.gla.ac.uk/researchinstitutes/biology/research/plantscience/#d.en.182661 University of Glasgow], UK. Supervisor- [http://www.gla.ac.uk/researchinstitutes/biology/staff/johnchristie/ Dr. John Christie] | ||
* 2004, B.A., [http://www.queens.ox.ac.uk/ The Queen's College], University of Oxford, UK | [http://theses.gla.ac.uk/147/ Thesis text] | ||
My graduate studies focused upon the plant blue light photoreceptor phototropin. Phototropin light sensitivity is derived from the action of two highly conserved regions known as LOV domains which upon light absorption induce activity of an integral serine/threonine kinase. My project examined the mechanism by which the LOV domains regulate kinase activity. I was able to show that the introduction of a point mutation within the second LOV domain was sufficient to mitigate light-mediated phototropin kinase activation. | |||
* 2001-2004, B.A. Biological Sciences, [http://www.queens.ox.ac.uk/ The Queen's College], University of Oxford, UK | |||
<br> | |||
==Awards and Scholarships== | |||
* 2012-2015 Leverhulme Early Career Fellow [http://www.leverhulme.ac.uk Leverhulme Trust] | |||
* 2011-2012 UC Davis "Professors for the Future" Fellow [http://gradstudies.ucdavis.edu/pftf/index.html UC Davis] | |||
* 2011 Keystone Symposia Scholarship to attend 'Histone Code: Fact or Fiction?' [http://www.keystonesymposia.org Keystone Symposia] | |||
* 2010 NAASC Travel Grant to attend ICAR 2010 [http://www.arabidopsis.org/portals/masc/countries/NAASC_Info.jsp NAASC] | |||
* 2004-2007 Sainsbury Plant Science PhD Studentship [http://www.gatsby.org.uk/en/Plant-Science.aspx Gatsby Charitable Foundation] | |||
* 2003-2004 Michel Exhibition [http://www.queens.ox.ac.uk/ The Queen's College] | |||
< | <br> | ||
==Publications== | ==Publications== | ||
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications. You can add or remove lines as needed --> | <!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications. You can add or remove lines as needed --> | ||
#Rawat R, Takahashi N, Hsu PY, '''Jones MA''', Schwartz J, Salemi MR, Phinney BS, Harmer SL (2011)''REVEILLE8 and PSEUDO-REPONSE REGULATOR5 Form a Negative Feedback Loop within the Arabidopsis Circadian Clock''. PLoS Genet 7(3): e1001350 [http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1001350] | |||
# | #'''Jones MA''', Harmer SL (2011) ''JMJD5 Functions in Concert with TOC1 in the Arabidopsis Circadian System''. Plant Signal Behav 6(3):445-448[http://www.landesbioscience.com/journals/psb/article/14654/] | ||
# | #'''Jones MA''', Covington MF, Ditacchio L, Vollmers C, Panda S, Harmer SL (2010) ''Jumonji Domain Protein JMJD5 Functions in Both the Plant and Human Circadian Systems''. PNAS 107(50):21623-21628 [http://www.pnas.org/content/107/50/21623.full] | ||
// | #Kaiserli E, Sullivan S, '''Jones MA''', Feeney KA, Christie JM (2009)'' Domain Swapping to Assess the Mechanistic Basis of Arabidopsis Phototropin 1 Receptor Kinase Activation and Endocytosis by Blue Light.'' Plant Cell 21:3226-3244 [http://www.plantcell.org/cgi/content/full/21/10/3226] | ||
# | #Rawat R, Schwartz J, '''Jones MA''', Sairanen I, Cheng Y, Andersson CR, Zhao Y, Ljung K, Harmer SL (2009) ''REVEILLE1, a Myb-like transcription factor, integrates the circadian clock and auxin pathways.'' PNAS 106 (39):16883-16888 [http://www.pnas.org/content/106/39/16883.long] | ||
#'''Jones MA''' (2009). ''Entrainment of the Arabidopsis Circadian Clock.'' J Plant Biol 52(3): 202-209 [http://www.springerlink.com/content/u30561q53l770734/?p=0b3372095be747bc83c7b13cd46fc8c3&pi=0] | |||
#Sullivan S, Thomson CE, Lamont DJ, '''Jones MA''', Christie JM (2008) ''In vivo phosphorylation site mapping and functional characterization of Arabidopsis phototropin 1.'' Mol Plant 1(1):178–194 [http://mplant.oxfordjournals.org/content/1/1/178.full?view=long&pmid=20031924] | |||
#'''Jones MA''', Christie JM (2008) ''Phototropin receptor kinase activation by blue light.'' Plant Signal Behav 3(1):44‐46 [http://www.landesbioscience.com/journals/psb/article/4848/] | |||
#'''Jones MA''', Feeney KA, Kelly SM, Christie JM (2007) ''Mutational analysis of phototropin 1 provides insights into the mechanism underlying LOV2 signal transmission'' J Biol Chem 282(9):6405-14 [http://www.jbc.org/content/282/9/6405.long] | |||
[http://www3.clustrmaps.com/user/ff18b123 http://www3.clustrmaps.com/stats/maps-no_clusters/openwetware.org-wiki-User-Matthew_A._Jones-thumb.jpg] | |||
__NOTOC__ | |||
Latest revision as of 06:55, 30 July 2012
Contact Info
Harmer Lab,
1002 Life Sciences Addition,
UC Davis,
One Shields Avenue,
Davis, CA 95616
majonesatucdavisdotedu
Research interests
The circadian clock acts to optimise the cellular behaviour of an organism so that it corresponds with the predictable environmental variation induced by the diurnal cycle. Whilst extensive genetic analyses have identified multiple genes involved in the plant circadian clock the precise mechanism by which these factors interact remains unclear. My current work involves characterisation of additional components of the plant circadian clock which will provide further insight into the workings of the central oscillator.
 Some of the feedback loops that form the Arabidopsis circadian clock. See [1] for more detail |
Education
- 2004-2007, PhD, University of Glasgow, UK. Supervisor- Dr. John Christie
My graduate studies focused upon the plant blue light photoreceptor phototropin. Phototropin light sensitivity is derived from the action of two highly conserved regions known as LOV domains which upon light absorption induce activity of an integral serine/threonine kinase. My project examined the mechanism by which the LOV domains regulate kinase activity. I was able to show that the introduction of a point mutation within the second LOV domain was sufficient to mitigate light-mediated phototropin kinase activation.
- 2001-2004, B.A. Biological Sciences, The Queen's College, University of Oxford, UK
Awards and Scholarships
- 2012-2015 Leverhulme Early Career Fellow Leverhulme Trust
- 2011-2012 UC Davis "Professors for the Future" Fellow UC Davis
- 2011 Keystone Symposia Scholarship to attend 'Histone Code: Fact or Fiction?' Keystone Symposia
- 2010 NAASC Travel Grant to attend ICAR 2010 NAASC
- 2004-2007 Sainsbury Plant Science PhD Studentship Gatsby Charitable Foundation
- 2003-2004 Michel Exhibition The Queen's College
Publications
- Rawat R, Takahashi N, Hsu PY, Jones MA, Schwartz J, Salemi MR, Phinney BS, Harmer SL (2011)REVEILLE8 and PSEUDO-REPONSE REGULATOR5 Form a Negative Feedback Loop within the Arabidopsis Circadian Clock. PLoS Genet 7(3): e1001350 [2]
- Jones MA, Harmer SL (2011) JMJD5 Functions in Concert with TOC1 in the Arabidopsis Circadian System. Plant Signal Behav 6(3):445-448[3]
- Jones MA, Covington MF, Ditacchio L, Vollmers C, Panda S, Harmer SL (2010) Jumonji Domain Protein JMJD5 Functions in Both the Plant and Human Circadian Systems. PNAS 107(50):21623-21628 [4]
- Kaiserli E, Sullivan S, Jones MA, Feeney KA, Christie JM (2009) Domain Swapping to Assess the Mechanistic Basis of Arabidopsis Phototropin 1 Receptor Kinase Activation and Endocytosis by Blue Light. Plant Cell 21:3226-3244 [5]
- Rawat R, Schwartz J, Jones MA, Sairanen I, Cheng Y, Andersson CR, Zhao Y, Ljung K, Harmer SL (2009) REVEILLE1, a Myb-like transcription factor, integrates the circadian clock and auxin pathways. PNAS 106 (39):16883-16888 [6]
- Jones MA (2009). Entrainment of the Arabidopsis Circadian Clock. J Plant Biol 52(3): 202-209 [7]
- Sullivan S, Thomson CE, Lamont DJ, Jones MA, Christie JM (2008) In vivo phosphorylation site mapping and functional characterization of Arabidopsis phototropin 1. Mol Plant 1(1):178–194 [8]
- Jones MA, Christie JM (2008) Phototropin receptor kinase activation by blue light. Plant Signal Behav 3(1):44‐46 [9]
- Jones MA, Feeney KA, Kelly SM, Christie JM (2007) Mutational analysis of phototropin 1 provides insights into the mechanism underlying LOV2 signal transmission J Biol Chem 282(9):6405-14 [10]
