User:Maureen McKeague: Difference between revisions

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#Chang A.L.; McKeague, M.; Liang, J.C.; Smolke, C.D. [http://pubs.acs.org/doi/abs/10.1021/ac5001527 Kinetic and Equilibrium Binding Characterization of Aptamers to Small Molecules using a Label-Free, Sensitive, and Scalable Platform], Analytical Chemistry, 2014, 86 (7), 3273–3278.
#Chang A.L.; McKeague, M.; Liang, J.C.; Smolke, C.D. [http://pubs.acs.org/doi/abs/10.1021/ac5001527 Kinetic and Equilibrium Binding Characterization of Aptamers to Small Molecules using a Label-Free, Sensitive, and Scalable Platform], Analytical Chemistry, 2014, 86 (7), 3273–3278.
#Mastronardi, E.; McKeague, M.; Monreal, C.; DeRosa, M.C. [http://www.tandfonline.com/doi/abs/10.1080/07391102.2013.786381?queryID=%24%7BresultBean.queryID%7D#.U72ysvldWv8 Development and Application of Crop Exudate Specific Aptamers], Journal of Biomolecular Structure and Dynamics, 2013, 31, 89.
#McKeague, M.; Foster, A.; Miguel, Y.; Giamberardino, A.; Verdin, C.; Chan, J.Y.; DeRosa, M.C. [http://pubs.rsc.org/en/content/articlelanding/2013/ra/c3ra43893g#!divAbstract/ Development of a DNA aptamer for direct and selective homocysteine detection in human serum], RSC Advances, 2013, 3, 24415-24422.
#McKeague, M.; Foster, A.; Miguel, Y.; Giamberardino, A.; Verdin, C.; Chan, J.Y.; DeRosa, M.C. [http://pubs.rsc.org/en/content/articlelanding/2013/ra/c3ra43893g#!divAbstract/ Development of a DNA aptamer for direct and selective homocysteine detection in human serum], RSC Advances, 2013, 3, 24415-24422.
#McKeague, M.; DeRosa, M.C. [http://www.hindawi.com/journals/jna/2012/748913/cta/ Challenges and Opportunities for Small Molecule Aptamer Development], Journal of Nucleic Acids, 2012.  
#McKeague, M.; DeRosa, M.C. [http://www.hindawi.com/journals/jna/2012/748913/cta/ Challenges and Opportunities for Small Molecule Aptamer Development], Journal of Nucleic Acids, 2012.  

Revision as of 16:25, 9 July 2014

Contact Info

Maureen McKeague

Maureen McKeague
Stanford University
Shriram Center, Room 244
443 Via Ortega
Stanford, CA 94305
Email me through OpenWetWare

I work in the Smolke lab

Education

Research interests

My past, current, and future research aims to improve the workflow of the selection and characterization of small molecule-binding aptamers towards the ultimate goal of developing both in vitro and in vivo biosensors that link important metabolite concentrations to readily detectable signals for high throughput screening and diagnostics.

Publications

  1. Chang A.L.; McKeague, M.; Liang, J.C.; Smolke, C.D. Kinetic and Equilibrium Binding Characterization of Aptamers to Small Molecules using a Label-Free, Sensitive, and Scalable Platform, Analytical Chemistry, 2014, 86 (7), 3273–3278.
  2. Mastronardi, E.; McKeague, M.; Monreal, C.; DeRosa, M.C. Development and Application of Crop Exudate Specific Aptamers, Journal of Biomolecular Structure and Dynamics, 2013, 31, 89.
  3. McKeague, M.; Foster, A.; Miguel, Y.; Giamberardino, A.; Verdin, C.; Chan, J.Y.; DeRosa, M.C. Development of a DNA aptamer for direct and selective homocysteine detection in human serum, RSC Advances, 2013, 3, 24415-24422.
  4. McKeague, M.; DeRosa, M.C. Challenges and Opportunities for Small Molecule Aptamer Development, Journal of Nucleic Acids, 2012.
  5. Cruz-Toledo, J.; McKeague, M.; Zhang, X.; Giamberardino, A.; McConnell, E.; Francis, T.; DeRosa, M.C.; Dumontier, M. Aptamer Base: A collaborative knowledge base to describe aptamers and SELEX experiments. Database: Journal of Biological Databases and Curation. 2012.
  6. McKeague, M.; Giamberardino, A.; DeRosa, M.C. Advances in Aptamer-Based Biosensors for Food Safety, Environmental Biosensors. 2011, Vernon Somerset (Ed.) ISBN: 9789533074863, InTech.
  7. De Girolamo, A.; McKeague, M.; Miller, J.D.; DeRosa, M.C.; Visconti, A. Determination of Ochratoxin A in Wheat After Clean-Up through a DNA Aptamer-Based Solid Phase Extraction Column. Food Chem. 2011, 127, 1378-1384.
  8. McKeague, M.; Bradley, C.R.; De Girolamo, A.; Visconti, A.; Miller, J.D.; Derosa, M.C. Screening and Initial Binding Assessment of Fumonisin B(1) Aptamers. Int. J. Mol. Sci. 2010, 11, 4864-4881.
  9. Luo, X.; McKeague, M.; Pitre, S.; Dumontier, M.; Green, J.; Golshani, A.; Derosa, M.C.; Dehne, F. Computational Approaches Toward the Design of Pools for the in Vitro Selection of Complex Aptamers. RNA. 2010, 16, 2252-2262.

Useful links

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