User:Nikolai Slavov: Difference between revisions
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==Contact Info== | ==Contact Info== | ||
[[Image:OWWEmblem.png|thumb|right|Nikolai Slavov (an artistic interpretation)]] | [[Image:OWWEmblem.png|thumb|right|Nikolai Slavov (an artistic interpretation)]] | ||
*Nikolai Slavov | *Nikolai Slavov | ||
* | *Massachusetts Institute of Technology | ||
* | *68-359 | ||
* | *77 Massachusetts Ave Cambridge, MA 02139 | ||
* | *http://mit.edu/nslavov/www/index.htm | ||
*[[Special:Emailuser/Nikolai Slavov|Email me through OpenWetWare]] | *[[Special:Emailuser/Nikolai Slavov|Email me through OpenWetWare]] | ||
I work in the [[Your Lab]] at XYZ University. I learned about [[OpenWetWare]] from from a friend, and I've joined because add protocols. | <!--I work in the [[Your Lab]] at XYZ University. I learned about [[OpenWetWare]] from from a friend, and I've joined because add protocols. --> | ||
==Education== | ==Education== | ||
<!--Include info about your educational background--> | <!--Include info about your educational background--> | ||
* | * 2010, PhD, Princeton University | ||
* | * 2006, MS, Princeton University | ||
* | * 2004, BS, MIT | ||
==Research interests== | ==Research interests== | ||
<!-- Feel free to add brief descriptions to your research interests as well --> | <!-- Feel free to add brief descriptions to your research interests as well --> | ||
# | # I am interested in the dynamics of cell growth, metabolic and regulatory processes during the eukaryotic cell division cycle (CDC), across a wide range of CDC periods. In particular, I study how the growth rate signal - which is function of the availability of nutrients and growth factors - regulates the switch between respiration and fermentation and changes the duration of phases of the cell growth and division cycles. | ||
# Interest 2 | |||
<!--# Interest 2 --> | |||
==Publications== | ==Publications== | ||
<!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications. You can add or remove lines as needed --> | <!-- Replace the PubMed ID's ("pmid=#######") below with the PubMed ID's for your publications. You can add or remove lines as needed --> | ||
<biblio> | <biblio> | ||
# | #Paper pmid=22065748 | ||
#Paper2 pmid= | #Paper2 pmid=21525243 | ||
// | //We discovered that the relative durations of the phases of the yeast metabolic cycle change with the growth rate. These changes can explain mechanistically the transcriptional growth-rate responses of all yeast genes (25% of the genome) that we find to be the same across all studied nutrient limitations in either ethanol or glucose carbon source. | ||
#Book1 isbn=0879697164 | #Paper1 pmid=19246374 | ||
<!-- #Book1 isbn=0879697164 --> | |||
</biblio> | </biblio> | ||
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==Useful links== | ==Useful links== | ||
*[[OpenWetWare:Welcome|Introductory tutorial]] | *[[OpenWetWare:Welcome|Introductory tutorial]] | ||
*[[Help|OpenWetWare help pages]] | *[[Help|OpenWetWare help pages]] --> | ||
Revision as of 14:21, 26 December 2011
Contact Info
- Nikolai Slavov
- Massachusetts Institute of Technology
- 68-359
- 77 Massachusetts Ave Cambridge, MA 02139
- http://mit.edu/nslavov/www/index.htm
- Email me through OpenWetWare
Education
- 2010, PhD, Princeton University
- 2006, MS, Princeton University
- 2004, BS, MIT
Research interests
- I am interested in the dynamics of cell growth, metabolic and regulatory processes during the eukaryotic cell division cycle (CDC), across a wide range of CDC periods. In particular, I study how the growth rate signal - which is function of the availability of nutrients and growth factors - regulates the switch between respiration and fermentation and changes the duration of phases of the cell growth and division cycles.
Publications
- Slavov N, Macinskas J, Caudy A, and Botstein D. Metabolic cycling without cell division cycling in respiring yeast. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19090-5. DOI:10.1073/pnas.1116998108 |
- Slavov N and Botstein D. Coupling among growth rate response, metabolic cycle, and cell division cycle in yeast. Mol Biol Cell. 2011 Jun 15;22(12):1997-2009. DOI:10.1091/mbc.E11-02-0132 |
We discovered that the relative durations of the phases of the yeast metabolic cycle change with the growth rate. These changes can explain mechanistically the transcriptional growth-rate responses of all yeast genes (25% of the genome) that we find to be the same across all studied nutrient limitations in either ethanol or glucose carbon source.
- Slavov N and Dawson KA. Correlation signature of the macroscopic states of the gene regulatory network in cancer. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4079-84. DOI:10.1073/pnas.0810803106 |
