User:Noppadon Sathitsuksanoh

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{{Tik}}
{{Tik}}
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[[File:Tik1.jpg|150px|thumb|left|<center>Tik1</center>]]
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[[Image:Tik1.jpg|150px|thumb|left|<center>Tik held a bottle of booze from fermented switchgrass using engineered ''Bacillus subtilis.'' Thanks, Xiaozhou!</center>]]
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;'''Noppadon Sathitsuksanoh (Tik)'''
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Postdoctoral Fellow
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Joint BioEnergy Institute
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Lawrence Berkeley National Laboratory
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;1 Cyclotron Rd.
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;MS: 978-4121
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Berkeley, CA 94720
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[mailto:Nsathitsuksanoh@lbl.gov Nsathitsuksanoh@lbl.gov]
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Website: [http://www.xiaozhouzhang.com/tik/biofuels tik's world]
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Noppadon Sathitsuksanoh (Tik)
 
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Ph.D. candidate
 
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;200 Seitz Hall
 
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Biological Systems Engineering Department
 
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Virginia Tech
 
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Blacksburg, VA 24061
 
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<br>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;[mailto:sathino@vt.edu sathino@vt.edu]
 
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==Primary Research==
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==<center>Summary</center>==
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The theme of my research lies upon conversion of lignocellulosic biomass to building blocks for fuels and bioproducts. My diverse background allows me to interface chemistry, biology, and engineering as well as economics for development of green and efficient yet economical processes using a combination of enzymes and novel solid catalysts.
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==<center>Primary Research</center>==
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#Biomass saccharification for productions of biofuels and bioproducts
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#Acid/base functionalized solid catalysts for integrated hydrolysis and hydrogenation of biomass components
 +
#Tunable physiochemical properties of biomass that affect their chemical and biological functions
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#Encapsulation of ZnO nanoparticles and their tailorable optical properties
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#CO<sub>2</sub> and H<sub>2</sub>S removal via novel entrapped/doped solid sorbents
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#Establishment and application of new genetic engineering tools and expression/secretion systems in ''Bacillus subtilis'', ''Geobacillus'' and ''Brevibacillus brevis''.
 
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#Metabolism and metabolic engineering of ''Bacillus subtilis''.
 
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#Enzyme Engineering by directed evolution: A novel powerful and highly efficient ''Bacillus subtilis'' platform for cellulase engineering and performance improvement towards natural cellulose substrate has been established.
 
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#Construction of recombinant consolidated bioprocessing (CBP) microorganisms (e.g., ''Bacillus'', ''Geobacillus'' and yeast) for one-step production of biocommodities from renewable lignocellulosic materials.
 
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#Synthetic biology and metabolic engineering for biofuel production from biomass.
 
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#Microbiological resources and ''in situ'' biodegradation.
 
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==Selected Publications==
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==<center>Five Representative Publications</center>==
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#'''Zhang, X.-Z.''', Sathitsuksanoh, N.,Zhu, Z. and Zhang, Y.-H. P. (2011) One-step production of lactate from cellulose as sole carbon source without any other organic nutrient by recombinant cellulolytic ''Bacillus subtilis'', under review.
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#'''Sathitsuksanoh N.''', Zhu Z., Wi S., Zhang YHP. Cellulose Solvent-Based Biomass Pretreatment Breaks Highly Ordered Hydrogen Bonds in Cellulose Fibers of Switchgrass. '''''Biotechnology & Bioengineering''''', DOI: 10.1002/bit.22964.
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#Myung, S., '''Zhang, X.-Z.''', and Zhang, Y.-H. P. (2011) Ultra-stable phosphoglucose isomerase through immobilization of cellulosebinding module-tagged thermophilic enzyme on low-cost high-capacity cellulosic adsorbent, '''Biotechnology Progress''' In Press
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#'''Sathitsuksanoh N.*''', Wang D., Yang H.Y., Lu Y., and Park M. 2010. Photoluminescent Properties of Encapsulated ZnO in Porous Carbon Matrix. '''''Acta Materialia''''' 58: 373-378
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#'''Zhang, X.-Z.''', and Zhang, Y.-H. P. (2011) Simple, fast and high-efficiency transformation system for directed evolution of cellulase in ''Bacillus subtilis'', '''Microbial Biotechnology''' 4, 98-105.
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#'''Sathitsuksanoh N.''', Zhu Z., Templeton N., Rollin J., Harvey S., Zhang Y-HP. 2009. Saccharification of a potential bioenergy crop, Phragmites australis (common reed), by lignocellulose fractionation followed by enzymatic hydrolysis at decreased cellulase loadings. '''''Industrial & Engineering Chemistry Research''''' 48: 6441-6447.
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#'''Zhang, X.-Z.''', Zhang, Z., Zhu, Z., Sathitsuksanoh, N., Yang, Y., and Zhang, Y.-H. P. (2010) The non-cellulosomal family 48 cellobiohydrolase from ''Clostridium phytofermentans'' ISDg: heterologous expression, characterization, and processivity, '''Applied Microbiology and Biotechnology''' 86, 525-533.
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#'''Sathitsuksanoh N.''', Yang H.Y., Cahela D.R., and Tatarchuk B.J. 2007 Immobilization of CO<sub>2</sub> by Aqueous K<sub>2</sub>CO<sub>3</sub> Using Microfibrous Media Entrapped Small Particulates for Battery and Fuel Cell Applications.  '''''Journal of Power Sources''''' 173: 478-4.
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#'''Zhang, X.-Z.''', and Zhang, Y.-H. P. (2010) One-step production of biocommodities from lignocellulosic biomass by recombinant cellulolytic ''Bacillus subtilis'': Opportunities and challenges, '''Engineering in Life Sciences''' 10(5):398-406.
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#Mondal K., '''Sathitsuksanoh N.''', Lalvani S.B. 2003. Extended X-ray Absorption Fine Structure Analysis of Ni-P and Fe-P Amorphous Alloys at the Phosphorous K-edge. '''''Journal of Materials Science Letters''''' 22(2): 95-97.
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#'''Zhang, X.-Z.''', Sathitsuksanoh, N., and Zhang, Y.-H. P. (2010) Glycoside hydrolase family 9 processive endoglucanase from ''Clostridium phytofermentans'': heterologous expression, characterization, and synergy with family 48 cellobiohydrolase, '''Bioresource Technology''' 101, 5534-5538.
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#Liu, W., '''Zhang, X.-Z.''', Zhang, Z., and Zhang, Y.-H. P. (2010) Engineering of ''Clostridium phytofermentans'' endoglucanase Cel5A for improved thermostability, '''Appl. Environ. Microbiol.''' 76, 4914-4917.
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#'''Zhang, X.-Z.''', Yan, X., Cui, Z. L., Hong, Q., and Li, S. P. (2006) ''mazF'', a novel counter-selectable marker for unmarked chromosomal manipulation in ''Bacillus subtilis'', '''Nucleic Acids Res''' 34, e71.
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#'''Zhang, X.-Z.''', Cui, Z.-L., Hong, Q., and Li, S.-P. (2005) High-level expression and secretion of methyl parathion hydrolase in ''Bacillus subtilis'' WB800, '''Appl. Environ. Microbiol.''' 71, 4101-4103.
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#Cui, Z.-L., '''Zhang, X.-Z.''', Zhang, Z.-H., and Li, S.-P. (2004) Construction and application of a promoter trapping vector with methyl parathion hydrolase gene ''mpd'' as the reporter, '''Biotechnology Letters''' 26, 1115-1118.
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Revision as of 01:39, 21 March 2013

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Tik held a bottle of booze from fermented switchgrass using engineered Bacillus subtilis. Thanks, Xiaozhou!
Tik held a bottle of booze from fermented switchgrass using engineered Bacillus subtilis. Thanks, Xiaozhou!


            Noppadon Sathitsuksanoh (Tik)
            Postdoctoral Fellow
            Joint BioEnergy Institute
            Lawrence Berkeley National Laboratory
            1 Cyclotron Rd.
            MS: 978-4121
            Berkeley, CA 94720
            Nsathitsuksanoh@lbl.gov
            Website: tik's world







Summary

The theme of my research lies upon conversion of lignocellulosic biomass to building blocks for fuels and bioproducts. My diverse background allows me to interface chemistry, biology, and engineering as well as economics for development of green and efficient yet economical processes using a combination of enzymes and novel solid catalysts.


Primary Research

  1. Biomass saccharification for productions of biofuels and bioproducts
  2. Acid/base functionalized solid catalysts for integrated hydrolysis and hydrogenation of biomass components
  3. Tunable physiochemical properties of biomass that affect their chemical and biological functions
  4. Encapsulation of ZnO nanoparticles and their tailorable optical properties
  5. CO2 and H2S removal via novel entrapped/doped solid sorbents


Five Representative Publications

  1. Sathitsuksanoh N., Zhu Z., Wi S., Zhang YHP. Cellulose Solvent-Based Biomass Pretreatment Breaks Highly Ordered Hydrogen Bonds in Cellulose Fibers of Switchgrass. Biotechnology & Bioengineering, DOI: 10.1002/bit.22964.
  2. Sathitsuksanoh N.*, Wang D., Yang H.Y., Lu Y., and Park M. 2010. Photoluminescent Properties of Encapsulated ZnO in Porous Carbon Matrix. Acta Materialia 58: 373-378
  3. Sathitsuksanoh N., Zhu Z., Templeton N., Rollin J., Harvey S., Zhang Y-HP. 2009. Saccharification of a potential bioenergy crop, Phragmites australis (common reed), by lignocellulose fractionation followed by enzymatic hydrolysis at decreased cellulase loadings. Industrial & Engineering Chemistry Research 48: 6441-6447.
  4. Sathitsuksanoh N., Yang H.Y., Cahela D.R., and Tatarchuk B.J. 2007 Immobilization of CO2 by Aqueous K2CO3 Using Microfibrous Media Entrapped Small Particulates for Battery and Fuel Cell Applications. Journal of Power Sources 173: 478-4.
  5. Mondal K., Sathitsuksanoh N., Lalvani S.B. 2003. Extended X-ray Absorption Fine Structure Analysis of Ni-P and Fe-P Amorphous Alloys at the Phosphorous K-edge. Journal of Materials Science Letters 22(2): 95-97.
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