User:Norville: Difference between revisions

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==Objective: [http://www.sciam.com/article.cfm?articleID=0006160D-B90B-1CDA-B4A8809EC588EEDF&pageNumber=8&catID=4 A "Magic Machine" for Creating Membrane Protein Crystals Very Rapidly]==
I am interested in using a combination of approaches including biomolecular materials, synthetic biology, and electron crystallography (and with strong foundations in molecular biology and biochemistry) in order to create a general method for building protein crystals (particularly for membrane proteins) in a deterministic fashion.


I think that most of the technology to create this "magic machine" or tool for creating membrane protein crystals already exists, however, it will take some time to put all the pieces together and creating a working prototype.
==Undergraduate Students==
 
==Undergraduate Students (Current)==
John Healy (formerly of the Axel Lab)<br>
 
==Undergraduate Students (Alumni)==
Victoria Chou<br>
Victoria Chou<br>
Debra Lin <br>
Debra Lin <br>
Nomeda Girnius<br>
Nomeda Girnius<br>
John Healy<br>




==Publications==


[http://openwetware.mit.edu/index.php?title=Bioinformatics_of_S-layer_Proteins Bioinformatics of S-layer Proteins]
Julie E. Norville, Deborah F. Kelly, Thomas F. Knight, Angela M. Belcher, and Thomas Walz, “7 Å projection map of the S-layer protein sbpA obtained with trehalose embedded monolayer crystals.” Accepted by Journal of Structural Biology.


==Publications==
A. Amy Yu, Peter R. Stone, Julie E. Norville, Michael Vaughn, Eden J. Pacsial, Barry D. Bruce, Marc Baldo, Francisco M. Raymo, and Francesco Stellacci, A simple atomic force microscopy method for the visualization of polar and non-polar parts in thin organic films, Journal of Experimental Nanoscience, 1(1), 63-73, 2006.
(with others) Photoresist as a sacrificial layer by dissolution in acetone.
 
Micro Electro Mechanical Systems, 2001. MEMS 2001.
Rupa Das, Patrick J. Kiley, Michael Segal, Julie Norville, A. Amy Yu, Leyu Wang, Scott Trammell, L. Evan Reddick, Rajay Kumar, Francesco Stellacci, Nikolai Lebedev, Joel Schnur, Barry D. Bruce, Shuguang Zhang, and Marc Baldo. “Integration of Photosynthetic Protein Molecular Complexes in Solid-State Electronic Devices.” Nano Letters, 4 (6), 1079-1083, 2004. Among others, this article was featured in the November 11, 2004 New York Times article “Spinach Power Adds Muscle to Batteries” by Katie Zezima and the Nature news article “Could laptops run on spinach?” by Philip Ball, June 21, 2005.
 
Ken Walsh, Julie E. Norville, and Yu-Chong Tai, “Photoresist as a Sacrificial Layer by Dissolution in Acetone,” IEEE MEMS, Interlaken, Switzerland, January 21-25, 2001.

Latest revision as of 16:50, 18 July 2007

Biography

Ph.D. Candidate in Electrical Engineering and Computer Science at MIT.
My advisors are Tom Knight and Angela Belcher.
M.S. in Electrical Engineering and Computer Science at MIT, 2004
B.S. in Electrical Engineering from the California Institute of Technology, 2002

Contact information

Julie Norville
MIT CSAIL
32 Vassar Street, Room 32-311
Cambridge, MA 02139
USA
626.235.3751
norville AT mit DOT edu


Undergraduate Students

Victoria Chou
Debra Lin
Nomeda Girnius
John Healy


Publications

Julie E. Norville, Deborah F. Kelly, Thomas F. Knight, Angela M. Belcher, and Thomas Walz, “7 Å projection map of the S-layer protein sbpA obtained with trehalose embedded monolayer crystals.” Accepted by Journal of Structural Biology.

A. Amy Yu, Peter R. Stone, Julie E. Norville, Michael Vaughn, Eden J. Pacsial, Barry D. Bruce, Marc Baldo, Francisco M. Raymo, and Francesco Stellacci, A simple atomic force microscopy method for the visualization of polar and non-polar parts in thin organic films, Journal of Experimental Nanoscience, 1(1), 63-73, 2006.

Rupa Das, Patrick J. Kiley, Michael Segal, Julie Norville, A. Amy Yu, Leyu Wang, Scott Trammell, L. Evan Reddick, Rajay Kumar, Francesco Stellacci, Nikolai Lebedev, Joel Schnur, Barry D. Bruce, Shuguang Zhang, and Marc Baldo. “Integration of Photosynthetic Protein Molecular Complexes in Solid-State Electronic Devices.” Nano Letters, 4 (6), 1079-1083, 2004. Among others, this article was featured in the November 11, 2004 New York Times article “Spinach Power Adds Muscle to Batteries” by Katie Zezima and the Nature news article “Could laptops run on spinach?” by Philip Ball, June 21, 2005.

Ken Walsh, Julie E. Norville, and Yu-Chong Tai, “Photoresist as a Sacrificial Layer by Dissolution in Acetone,” IEEE MEMS, Interlaken, Switzerland, January 21-25, 2001.