Ph.D. Candidate in Electrical Engineering and Computer Science at MIT.
My advisors are Tom Knight and Angela Belcher.
M.S. in Electrical Engineering and Computer Science at MIT, 2004
B.S. in Electrical Engineering from the California Institute of Technology, 2002
32 Vassar Street, Room 32-311
Cambridge, MA 02139
norville AT mit DOT edu
Objective: A "Magic Machine*" for Creating Membrane Protein Crystals Very Rapidly
I am interested in using a combination of approaches including biomolecular materials, synthetic biology, and electron crystallography (and with strong foundations in molecular biology and biochemistry) in order to create a general method for building protein crystals (particularly for membrane proteins) in a deterministic fashion.
I think that most of the technology to create this "magic machine" or tool for creating membrane protein crystals already exists, however, it will take some time to put all the pieces together to create a working prototype.
Helping me in this adventure are my collaborators and undergraduate students.
- This "Magic Machine" is a device imagined by Roderick MacKinnon in the linked interview.
Advisors, Collaborators, and Influential Guides
Angela Belcher and the Belcher Lab
Tom Knight and the Knight Lab
Deborah Kelly and Tom Walz
Shuguang Zhang, Andreas Mershin, and the Zhang Lab
Malancha Gupta and Karen Gleason
The Gast Lab
The Tai Lab
The Instructors of the Cold Spring Harbor Protein Purification Course
Undergraduate Students (Current)
John Healy (formerly of the Axel Lab)
Interested undergraduates may contact me at norville at mit dot edu
Undergraduate Students (Alumni)
(with others) Photoresist as a sacrificial layer by dissolution in acetone. Micro Electro Mechanical Systems, 2001. MEMS 2001.
(with others) Integration of photosynthetic protein molecular complexes in solid-state electronic devices. Nano Lett, 2004