User:Odom:Schmidt

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Dominic Schmidt

Dominic Schmidt Doctoral Student; Department of Oncology, University of Cambridge Cancer Research UK Cambridge Research Institute Li Ka Shing Centre Robinson Way, Cambridge, CB2 0RE phone: +44-1223404248 email: Dominic.Schmidt 'at' cancer 'dot' org 'dot' uk

Research Interests I received my german diplom degree in Biochemistry at the Max Planck Institute for Molecular genetics in the department for Vertebrate Genomics of Hans Lehrach in the laboratory of Marie-Laure Yaspo. The focus of my research was the analysis of gene regulatory networks, especially for human chromosome 21 encoded transcription factors. For this purpose I worked with ChIP-chip using high density oligonucleotide microarrays and developed ChIP-seq using next generation sequencing technology. We recently published ChIP-seq for RNA-polymerase II in 293T cells together with RNA-seq of the same cells and the ramos b-cell-line: Sultan M, Schulz MH, Richard H, Magen A, Klingenhoff A, Scherf M, Seifert M, Borodina T, Soldatov A, Parkhomchuk D, Schmidt D, O'Keeffe S, Haas S, Vingron M, Lehrach H, and Yaspo ML. A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome. Science 2008 Jul 3. doi:10.1126/science.1160342 pmid:18599741. My recent research uses ChIP-seq and RNA-seq to understand the rules behind tissue-specific gene regulation. Coming soon...

Publications

Sultan M, Schulz MH, Richard H, Magen A, Klingenhoff A, Scherf M, Seifert M, Borodina T, Soldatov A, Parkhomchuk D, Schmidt D, O'Keeffe S, Haas S, Vingron M, Lehrach H, and Yaspo ML. A global view of gene activity and alternative splicing by deep sequencing of the human transcriptome. Science. 2008 Aug 15;321(5891):956-60. DOI:10.1126/science.1160342 |

Miscellaneous

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ChIP-seq Carroll-lab Odom-lab Cambridge punting