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== Omar F. Khan ==
== Omar F. Khan ==


[[Image:OF_Khan.jpg|thumb|left|Omar F. Khan]]
[[Image:KI.jpg|thumb|left|Omar F. Khan]]


Hi, my name is Omar F. Khan, and I'm currently at University of Toronto. I learned about [[OpenWetWare]] from Professor Axel Guenther, and I've joined because Fabrication of microfluidic devices.  You can [[Special:Emailuser/Omar F. Khan|email me through OpenWetWare]]. I am a serving member of the [http://openwetware.org/wiki/TorontoMicrofluidicsFoundry Toronto Microfluidic Foundry's] Process Technology Committee.
Hi, my name is [http://www.facebook.com/dr.ofk/ Omar F. Khan], and I'm currently at the [http://web.mit.edu/ Massachusetts Institute of Technology] in [http://web.mit.edu/langerlab/ Professor Robert Langer's lab] within the [http://ki.mit.edu David H. Koch Institute for Integrative Cancer Research].  I did my PhD at the [http://www.utoronto.ca University of Toronto] under the supervision of [http://www.ibbme.utoronto.ca/faculty/core/sefton.htm Professor Michael V. Sefton]. 
 
I work towards the treatment of damaged tissues and organs by combining nanotechnology and tissue engineering.  I learned about [[OpenWetWare]] from Professor Axel Guenther and served with him on the [http://openwetware.org/wiki/TorontoMicrofluidicsFoundry Toronto Microfluidic Foundry's] Process Technology Committee.  I've joined because I fabricate microfluidic devices.  You can [[Special:Emailuser/Omar F. Khan|email me through OpenWetWare]].
 
== Work ==
Postdoctoral Associate, Langer Lab, Massachusetts Institute of Technology


== Education ==
== Education ==


Ph.D., Chemical Engineering and Applied Chemistry/Institute of Biomaterials and Biomedical Engineering, University of Toronto (current)
Ph.D., Chemical Engineering and Applied Chemistry/Institute of Biomaterials and Biomedical Engineering, University of Toronto, 2010
 
B.A.Sc.(with honors), Chemical Engineering, University of Toronto, 2004
 
== Publications and Communications ==
'''Khan O.F.''', Chamberlain M.D. and Sefton M.V.  ''Toward an In Vitro Vasculature: Differentiation of Mesenchymal Stromal Cells Within an Endothelial Cell-Seeded Modular Construct in a Microfluidic Flow Chamber.''  Tissue Engineering Part A, 2011 Dec 2. [Epub ahead of print]
 
 
'''Khan, O.F.''' and Sefton, M.V.  ''Endothelialized biomaterials for tissue engineering applications in vivo.''  Trends in Biotechnology, 2011 Aug;29(8):379-87.
 
 
'''Khan, O.F.''' and Sefton, M.V.  ''Patterning Collagen/Poloxamine-Methacrylate Hydrogels for Tissue-Engineering-Inspired Microfluidic and Laser Lithography Applications.''  Journal of Biomaterial Science, DOI: 10.1163/092050610X540693, Epub ahead of print
 
 
Chamberlain, M.D., Butler, M.J., Ciucurel, E.C., Fitzpatrick, L.E., '''Khan, O.F.''', Leung, B.M., Lo, C., Patel, R., Velchinskaya, A., Voice, D.N. and Sefton, M.V.  ''Fabrication of Micro-Tissues using Modules of Collagen Gel Containing Cells.''  Journal of Visualized Experiments, DOI: 10.3791/2177
 
 
'''Khan, O.F.''' and Sefton, M.V.  ''Endothelial Cell Behaviour within a Microfluidic Mimic of the Flow Channels of a Modular Tissue Engineered Construct.''  Biomedical Microdevices, 2011 Feb;13(1):69-87.
 
 
'''Khan, O.F.''' and Sefton, M.V.  ''Perfusion and Characterization of an Endothelial Cell-Seeded Modular Tissue Engineered Construct Formed in a Microfluidic Remodeling Chamber.''  Biomaterials, 2010 Nov;31(32):8254-61


M.A.Sc., Chemical Engineering and Applied Chemistry/Institute of Biomaterials and Biomedical Engineering, University of Toronto, 2006


B.A.Sc. (Honors), Chemical Engineering, University of Toronto, 2004
'''Khan, O.F.''', Jean-Francois, J. and Sefton, M.V.  ''MMP Levels in the Response to Degradable Implants in the Presence of a Hydroxamate-Based Matrix Metalloproteinase Sequestering Biomaterial In Vivo.'' Journal of Biomedical Materials Research, Part A, 2010 Jun 15;93(4):1368-79.


== Publications and Communications ==
Khan, O.F. and Sefton, M.V.  Perfusion and Characterization of an Endothelial Cell-Seeded Modular Tissue Engineered Construct Formed in a Microfluidic Remodeling Chamber.  Biomaterials (In Press)


Khan, O.F., Jean-Francois, J. and Sefton, M.V. MMP levels in the response to degradable implants in the presence of a hydroxamate-based matrix metalloproteinase sequestering biomaterial in vivo. Journal of Biomedical Materials Research, Part A, 2010 Jun 15;93(4):1368-79.
Sosnik A., '''Khan O.F.''', Butler M, Sefton M.V.: ''Poloxamine hydrogels: From non-cell adhesive substrates to matrices with improved cytocompatibility for Tissue Engineering applications.'' In Barbucci, R. (Ed.), Hydrogels: Biological Properties and Applications. Springer; 2009.
 
 
 
'''Khan, O.F.''', Chamberlain, M.D., Dahlman, J.E., Sefton, M.V., Langer, R.S. and Anderson, D.G. "Modular Tissue Containing Endothelial and Mesenchymal Stem Cells formed in a Microfluidic Perfusion Chamber."  The 11th US-Japan Symposium on Drug Delivery Systems Conference, Lahaina, Maui, USA, December 16-20, 2011.  Poster Presentation 
 
 
Voice, D.N., '''Khan, O.F.''', Leung, B.M. and Sefton, M.V. “High throughput module production and applications to cardiac tissue engineering.” Ontario-on-a-Chip, Toronto, Ontario, Canada, June 9-10, 2011. Poster Presentation
 


Sosnik A., Khan O.F., Butler M, Sefton M.V.: Poloxamine hydrogels: From non-cell adhesive substrates to matrices with improved cytocompatibility for Tissue Engineering applications. In Barbucci, R. (Ed.), Hydrogels: Biological Properties and Applications. Springer; 2009.
Voice, D.N., '''Khan, O.F.''', Leung, B.M. and Sefton, M.V. “A novel plug flow process for high throughput modular tissue engineering.” Canadian Biomaterials Society, 29th Annual Conference, Vancouver, British Columbia, Canada, June 1-4, 2011. Oral presentation


Khan, O.F., Chamberlain, M.D. and Sefton, M.V. “Modular Tissue Containing Endothelial Cells and Mesenchymal Stem Cells formed in a Microfluidic Perfusion Chamber.”  Tissue Engineering and Regenerative Medicine International Society (TERMIS)-EU Chapter Meeting, Galway, Ireland, June 13-17, 2010.  Oral Presentation


Khan, O.F., Leung, B.M. and Sefton, M.V. “Modular Cardiac Tissue Containing Endothelial and Cardiomyocyte Cells formed in a Microfluidic Perfusion Chamber,” Ontario-on-a-Chip, Toronto, ON., Canada, May 20-21, 2010.  Oral Presentation


Khan, O.F. and Sefton, M.V. “Collagen/Poloxamine Microfluidic Flow Circuits to Characterize Surface-Attached Endothelial Cells Under Flow.”  8th World Biomaterials Congress, Amsterdam, The Netherlands, May 28-June 1, 2008. Oral Presentation
'''Khan, O.F.''', Chamberlain, M.D. and Sefton, M.V. “Modular Tissue Containing Endothelial Cells and Mesenchymal Stem Cells formed in a Microfluidic Perfusion Chamber.”  Tissue Engineering and Regenerative Medicine International Society (TERMIS)-European Union Chapter Meeting, Galway, Ireland, June 13-17, 2010. Oral Presentation


Khan, O.F. and Sefton, M.V. “In Vivo Use of a Matrix Metalloproteinase-Sequestering Biomaterial to Alter the Inflammatory Response,” Regenerate World Congress on Tissue Engineering and Regenerative Medicine, Pittsburgh, Pennsylvania, USA, April 23-27, 2006.  Poster Presentation


== Lab Info ==
'''Khan, O.F.''', Leung, B.M. and Sefton, M.V. “Modular Cardiac Tissue Containing Endothelial and Cardiomyocyte Cells formed in a Microfluidic Perfusion Chamber,” Ontario-on-a-Chip, Toronto, ON., Canada, May 20-21, 2010.  Oral Presentation
Professor Michael V. Sefton, supervisor


Centre for Cellular and Biomolecular Research,


160 College Street, Room 440
'''Khan, O.F.''' and Sefton, M.V. “Collagen/Poloxamine Microfluidic Flow Circuits to Characterize Surface-Attached Endothelial Cells Under Flow.”  8th World Biomaterials Congress, Amsterdam, The Netherlands, May 28-June 1, 2008. Oral Presentation


Toronto, Ontario


Canada M5S3E1
'''Khan, O.F.''' and Sefton, M.V. “In Vivo Use of a Matrix Metalloproteinase-Sequestering Biomaterial to Alter the Inflammatory Response,” Regenerate World Congress on Tissue Engineering and Regenerative Medicine, Pittsburgh, Pennsylvania, USA, April 23-27, 2006.  Poster Presentation


[http://www.ibbme.utoronto.ca/faculty/core/sefton.htm Research Highlights]


== Basic Wiki Instructions ==
'''Khan, O.F.''' and Sefton, M.V. “In Vivo Alteration of the Foreign Body Response Using a Matrix Metalloproteinase-Sequestering Biomaterial,” Challenges in Regenerative Medicine (ChaRM), Toronto, Ontario, Canada, October 20-21, 2005. Poster Presentation
Editing pages:Here's an extensive list of [http://en.wikipedia.org/wiki/Wikipedia:Tutorial_%28Formatting%29 formating examples]. Or look at this OpenWetWare [[OpenWetWare:Welcome|introductory tutorial]].
For examples, check out [[User:Julius_B._Lucks]], [[User:Jason_R._Kelly]] and [[User:Reshma_P._Shetty]].

Revision as of 15:36, 21 December 2012

Omar F. Khan

Omar F. Khan

Hi, my name is Omar F. Khan, and I'm currently at the Massachusetts Institute of Technology in Professor Robert Langer's lab within the David H. Koch Institute for Integrative Cancer Research. I did my PhD at the University of Toronto under the supervision of Professor Michael V. Sefton.

I work towards the treatment of damaged tissues and organs by combining nanotechnology and tissue engineering. I learned about OpenWetWare from Professor Axel Guenther and served with him on the Toronto Microfluidic Foundry's Process Technology Committee. I've joined because I fabricate microfluidic devices. You can email me through OpenWetWare.

Work

Postdoctoral Associate, Langer Lab, Massachusetts Institute of Technology

Education

Ph.D., Chemical Engineering and Applied Chemistry/Institute of Biomaterials and Biomedical Engineering, University of Toronto, 2010

B.A.Sc.(with honors), Chemical Engineering, University of Toronto, 2004

Publications and Communications

Khan O.F., Chamberlain M.D. and Sefton M.V. Toward an In Vitro Vasculature: Differentiation of Mesenchymal Stromal Cells Within an Endothelial Cell-Seeded Modular Construct in a Microfluidic Flow Chamber. Tissue Engineering Part A, 2011 Dec 2. [Epub ahead of print]


Khan, O.F. and Sefton, M.V. Endothelialized biomaterials for tissue engineering applications in vivo. Trends in Biotechnology, 2011 Aug;29(8):379-87.


Khan, O.F. and Sefton, M.V. Patterning Collagen/Poloxamine-Methacrylate Hydrogels for Tissue-Engineering-Inspired Microfluidic and Laser Lithography Applications. Journal of Biomaterial Science, DOI: 10.1163/092050610X540693, Epub ahead of print


Chamberlain, M.D., Butler, M.J., Ciucurel, E.C., Fitzpatrick, L.E., Khan, O.F., Leung, B.M., Lo, C., Patel, R., Velchinskaya, A., Voice, D.N. and Sefton, M.V. Fabrication of Micro-Tissues using Modules of Collagen Gel Containing Cells. Journal of Visualized Experiments, DOI: 10.3791/2177


Khan, O.F. and Sefton, M.V. Endothelial Cell Behaviour within a Microfluidic Mimic of the Flow Channels of a Modular Tissue Engineered Construct. Biomedical Microdevices, 2011 Feb;13(1):69-87.


Khan, O.F. and Sefton, M.V. Perfusion and Characterization of an Endothelial Cell-Seeded Modular Tissue Engineered Construct Formed in a Microfluidic Remodeling Chamber. Biomaterials, 2010 Nov;31(32):8254-61


Khan, O.F., Jean-Francois, J. and Sefton, M.V. MMP Levels in the Response to Degradable Implants in the Presence of a Hydroxamate-Based Matrix Metalloproteinase Sequestering Biomaterial In Vivo. Journal of Biomedical Materials Research, Part A, 2010 Jun 15;93(4):1368-79.


Sosnik A., Khan O.F., Butler M, Sefton M.V.: Poloxamine hydrogels: From non-cell adhesive substrates to matrices with improved cytocompatibility for Tissue Engineering applications. In Barbucci, R. (Ed.), Hydrogels: Biological Properties and Applications. Springer; 2009.


Khan, O.F., Chamberlain, M.D., Dahlman, J.E., Sefton, M.V., Langer, R.S. and Anderson, D.G. "Modular Tissue Containing Endothelial and Mesenchymal Stem Cells formed in a Microfluidic Perfusion Chamber." The 11th US-Japan Symposium on Drug Delivery Systems Conference, Lahaina, Maui, USA, December 16-20, 2011. Poster Presentation


Voice, D.N., Khan, O.F., Leung, B.M. and Sefton, M.V. “High throughput module production and applications to cardiac tissue engineering.” Ontario-on-a-Chip, Toronto, Ontario, Canada, June 9-10, 2011. Poster Presentation


Voice, D.N., Khan, O.F., Leung, B.M. and Sefton, M.V. “A novel plug flow process for high throughput modular tissue engineering.” Canadian Biomaterials Society, 29th Annual Conference, Vancouver, British Columbia, Canada, June 1-4, 2011. Oral presentation


Khan, O.F., Chamberlain, M.D. and Sefton, M.V. “Modular Tissue Containing Endothelial Cells and Mesenchymal Stem Cells formed in a Microfluidic Perfusion Chamber.” Tissue Engineering and Regenerative Medicine International Society (TERMIS)-European Union Chapter Meeting, Galway, Ireland, June 13-17, 2010. Oral Presentation


Khan, O.F., Leung, B.M. and Sefton, M.V. “Modular Cardiac Tissue Containing Endothelial and Cardiomyocyte Cells formed in a Microfluidic Perfusion Chamber,” Ontario-on-a-Chip, Toronto, ON., Canada, May 20-21, 2010. Oral Presentation


Khan, O.F. and Sefton, M.V. “Collagen/Poloxamine Microfluidic Flow Circuits to Characterize Surface-Attached Endothelial Cells Under Flow.” 8th World Biomaterials Congress, Amsterdam, The Netherlands, May 28-June 1, 2008. Oral Presentation


Khan, O.F. and Sefton, M.V. “In Vivo Use of a Matrix Metalloproteinase-Sequestering Biomaterial to Alter the Inflammatory Response,” Regenerate World Congress on Tissue Engineering and Regenerative Medicine, Pittsburgh, Pennsylvania, USA, April 23-27, 2006. Poster Presentation


Khan, O.F. and Sefton, M.V. “In Vivo Alteration of the Foreign Body Response Using a Matrix Metalloproteinase-Sequestering Biomaterial,” Challenges in Regenerative Medicine (ChaRM), Toronto, Ontario, Canada, October 20-21, 2005. Poster Presentation