User:Pakpoom Subsoontorn/Notebook/Genetically Encoded Memory/2008/10/12: Difference between revisions
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# We also need some mechanism to partition continuous input signals into separated discrete signal. For a given signal [A] (say, we shine light to a cell for 10 min or grow the cell in high lactose), we need to make sure that the memory is flipped to [0XXXXXXX], not [00XXXXXX] nor [0000XXXX]. Somehow, we may need to have the mechanism to flip the lower bit to turn off before the mechanism to flip the next bit to turn on. Thus, if we give a continuous "A" signal once (no matter how long it is), only the first bit will be flip (resulting in [0XXXXXXX]). The second bit cannot be flipped to 0, because the mechanism of the first bit is still ON while "A" is present. Now, if we give two pulses of "A", two bit will be flipped because the mechanism for flipping the first bit is off when the second pulse of "A" arrive. | # We also need some mechanism to partition continuous input signals into separated discrete signal. For a given signal [A] (say, we shine light to a cell for 10 min or grow the cell in high lactose), we need to make sure that the memory is flipped to [0XXXXXXX], not [00XXXXXX] nor [0000XXXX]. Somehow, we may need to have the mechanism to flip the lower bit to turn off before the mechanism to flip the next bit to turn on. Thus, if we give a continuous "A" signal once (no matter how long it is), only the first bit will be flip (resulting in [0XXXXXXX]). The second bit cannot be flipped to 0, because the mechanism of the first bit is still ON while "A" is present. Now, if we give two pulses of "A", two bit will be flipped because the mechanism for flipping the first bit is off when the second pulse of "A" arrive. | ||
==Possible | ==Possible mechanisms for partitioning signals== | ||
* The following memory structure consists of memory units, writers, partitioner and three-input AND gates. | * The following memory structure consists of memory units, writers, partitioner and three-input AND gates. | ||
* Every bit of memory is connected to its specific writers. The number of writers per bit is equal to the number of possible digit that can be written in that bit. For example, a binary unit will need two writers for writing "0" and "1". In the figure below, we only show one writer that can write "0" on and empty bit. | * Every bit of memory is connected to its specific writers. The number of writers per bit is equal to the number of possible digit that can be written in that bit. For example, a binary unit will need two writers for writing "0" and "1". In the figure below, we only show one writer that can write "0" on and empty bit. |
Revision as of 23:49, 13 October 2008
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Implementing N-bit memory with DNA recombination
Rules
Abstract structures
Possible mechanisms for partitioning signals
Example-1:Intramolecular integration of plasmids |