User:Paul R Jaschke: Difference between revisions

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==Personal==
===Bio===
I am currently a post-doc in Drew Endy's lab at Stanford University. The focus of my project is to redesign phage using both rational and combinatorial methods to finish the genetics of a simple system.
I started off my science career in at the University of Alberta (Canada), working in the Casey and Michalak labs during this time. Summer student work in Casey Lab on the human sodium-bicarbonate co-transporter protein resulted in my first authorship in a peer-reviewed publication. My honors project in the Michalak Lab had me trying to determine the role of calcium signalling and calreticulin on murine embryonic stem cell differentiation into heart cells. After achieving a B.Sc. (Honors) in Biochemistry I went to the Beatty Lab at the University of British Columbia to start my Ph.D. While at UBC I discovered that a photosynthetic organism called Rhodobacter sphaeroides was capable of re-routing its chlorophyll biosynthetic machinery around a blockage to generate a new type of chlorophyll.


==Contact Info==
==Contact Info==
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[http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides ''Rhodobacter sphaeroides'' on Wikipedia]
[http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides ''Rhodobacter sphaeroides'' on Wikipedia]
==Other==
===Hobbies===
Beer Making
Snowboarding
Hiking & Camping

Revision as of 09:39, 9 January 2011

Back to Lab Members

Personal

Bio

I am currently a post-doc in Drew Endy's lab at Stanford University. The focus of my project is to redesign phage using both rational and combinatorial methods to finish the genetics of a simple system.

I started off my science career in at the University of Alberta (Canada), working in the Casey and Michalak labs during this time. Summer student work in Casey Lab on the human sodium-bicarbonate co-transporter protein resulted in my first authorship in a peer-reviewed publication. My honors project in the Michalak Lab had me trying to determine the role of calcium signalling and calreticulin on murine embryonic stem cell differentiation into heart cells. After achieving a B.Sc. (Honors) in Biochemistry I went to the Beatty Lab at the University of British Columbia to start my Ph.D. While at UBC I discovered that a photosynthetic organism called Rhodobacter sphaeroides was capable of re-routing its chlorophyll biosynthetic machinery around a blockage to generate a new type of chlorophyll.

Contact Info

Paul Jaschke

I work in the Endy Lab in the Department of Bioengineering

Education

2010 Ph.D. Microbiology and Immunology, University of British Columbia, Canada

2003 B.Sc. Honors Biochemistry, University of Alberta, Canada

Publications

Jaschke, PR. (2010). Discovery and characterization of a new zinc-bacteriochlorophyll biosynthetic pathway and photosystem in a magnesium-chelatase mutant. Thesis. University of British Columbia. Abstract PDF

Lin S, Jaschke PR, Wang H, Paddock M, Tufts A, Allen JP, Rosell FI, Mauk GA, Woodbury NW, Beatty JT. (2009). Electron transfer in the Rhodobacter sphaeroides reaction center assembled with zinc bacteriochlorophyll. Proc Natl Acad Sci USA.106(21): 8537-42. Abstract PDF

Jaschke PR, LeBlanc HN, Lang AS, Beatty JT. (2008). The PucC protein of Rhodobacter capsulatus mitigates an inhibitory effect of light-harvesting 2 alpha and beta proteins on light-harvesting complex 1. Photosynth Res. 95(2-3): 279-84. Abstract PDF

Jaschke PR, Beatty JT. (2007). The photosystem of Rhodobacter sphaeroides assembles with zinc bacteriochlorophyll in a bchD (magnesium chelatase) mutant. Biochemistry. 46(43): 12491-500. Abstract PDF

Loiselle FB, Jaschke P, Casey JR. (2003). Structural and functional characterization of the human NBC3 sodium/bicarbonate co-transporter carboxyl-terminal cytoplasmic domain. Mol Membr Biol. 20(4): 307-17. Abstract PDF

Presentations

Jaschke PR and Beatty JT. (2010). Out of the Blue. PDF

Jaschke PR and Beatty JT. (2007). Discovery of zinc-bacteriochlorophyll in Rhodobacter sphaeroides. PDF

Useful links

Mendeley Profile

LinkedIn Profile

Rhodobacter sphaeroides on Wikipedia

Other

Hobbies

Beer Making

Snowboarding

Hiking & Camping