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[[Endy:Lab Members|Back to Lab Members]]
[[Image:Pjaschke.jpg|thumb|right|Paul Jaschke]]
 
==Personal==
===Bio===
I am currently a post-doc in Drew Endy's lab at Stanford University. The focus of my project is to redesign phage using both rational and combinatorial methods in order to finish the genetics of a simple system.
 
I started off my science career at the University of Alberta (Canada), working in the Casey and Michalak labs. Summer student work in the Casey Lab on the human sodium-bicarbonate co-transporter protein resulted in an authorship in a peer-reviewed publication. My honors project in the Michalak Lab had me determining the role of calcium signalling and calreticulin on murine embryonic stem cell differentiation. After achieving a B.Sc. (Honors) in Biochemistry in 2003 I went to the Beatty Lab at the University of British Columbia to start my Ph.D. While at UBC I discovered that a photosynthetic organism called Rhodobacter sphaeroides was capable of re-routing its chlorophyll biosynthetic machinery around a blockage to generate a new type of chlorophyll. November 2010 I was conferred a Ph.D in Microbiology and Immunology from UBC.


==Contact Info==
==Contact Info==
[[Image:Pjaschke.jpg|thumb|right|Paul Jaschke)]]


*Paul R Jaschke
*Paul R Jaschke
*University of British Columbia
*Stanford University
*Vancouver, British Columbia  Canada
*Stanford, California, USA
*pjaschke 'AT' stanford.edu
*[[Special:Emailuser/Paul R Jaschke|Email me through OpenWetWare]]
*[[Special:Emailuser/Paul R Jaschke|Email me through OpenWetWare]]


I work in the Beatty Lab in the Department of Microbiology and Immunology
I work in the [[Endy Lab]] in the Department of Bioengineering


==Education==
==Education==
2010 Ph.D. Microbiology and Immunology, University of British Columbia, Canada
2003 B.Sc. Honors Biochemistry, University of Alberta, Canada
2003 B.Sc. Honors Biochemistry, University of Alberta, Canada


==Publications==
==Publications==
Jaschke, PR. (2010). Discovery and characterization of a new zinc-bacteriochlorophyll biosynthetic pathway and photosystem in a magnesium-chelatase mutant. PhD Thesis. University of British Columbia.
[https://circle.ubc.ca/handle/2429/27234 Abstract] [[Media:ubc_2010_fall_jaschke_paul.pdf|PDF]]


Lin S, Jaschke PR, Wang H, Paddock M, Tufts A, Allen JP, Rosell FI, Mauk GA, Woodbury NW, Beatty JT. (2009). Electron transfer in the ''Rhodobacter sphaeroides'' reaction center assembled with zinc bacteriochlorophyll. ''Proc Natl Acad Sci USA''.106(21): 8537-42. [http://www.ncbi.nlm.nih.gov/pubmed/19439660?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Abstract]
Lin S, Jaschke PR, Wang H, Paddock M, Tufts A, Allen JP, Rosell FI, Mauk GA, Woodbury NW, Beatty JT. (2009). Electron transfer in the ''Rhodobacter sphaeroides'' reaction center assembled with zinc bacteriochlorophyll. ''Proc Natl Acad Sci USA''.106(21): 8537-42. [http://www.ncbi.nlm.nih.gov/pubmed/19439660?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Abstract] [[Media:Lin-2009-PNAS.pdf|PDF]]


Jaschke PR, LeBlanc HN, Lang AS, Beatty JT. (2008). The PucC protein of ''Rhodobacter capsulatus'' mitigates an inhibitory effect of light-harvesting 2 alpha and beta proteins on light-harvesting complex 1. ''Photosynth Res''. 95(2-3): 279-84. [http://www.ncbi.nlm.nih.gov/pubmed/17922301?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Abstract]
Jaschke PR, LeBlanc HN, Lang AS, Beatty JT. (2008). The PucC protein of ''Rhodobacter capsulatus'' mitigates an inhibitory effect of light-harvesting 2 alpha and beta proteins on light-harvesting complex 1. ''Photosynth Res''. 95(2-3): 279-84. [http://www.ncbi.nlm.nih.gov/pubmed/17922301?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Abstract] [[Media:Jaschke-2008-Photosynth Res.pdf|PDF]]


Jaschke PR, Beatty JT. (2007). The photosystem of ''Rhodobacter sphaeroides'' assembles with zinc bacteriochlorophyll in a ''bchD'' (magnesium chelatase) mutant. ''Biochemistry''. 46(43): 12491-500. [http://www.ncbi.nlm.nih.gov/pubmed/17910480?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Abstract]
Jaschke PR, Beatty JT. (2007). The photosystem of ''Rhodobacter sphaeroides'' assembles with zinc bacteriochlorophyll in a ''bchD'' (magnesium chelatase) mutant. ''Biochemistry''. 46(43): 12491-500. [http://www.ncbi.nlm.nih.gov/pubmed/17910480?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Abstract] [[Media:Jaschke-2007-Biochemistry.pdf|PDF]]


Loiselle FB, Jaschke P, Casey JR. (2003). Structural and functional characterization of the human NBC3 sodium/bicarbonate co-transporter carboxyl-terminal cytoplasmic domain. ''Mol Membr Biol''. 20(4): 307-17. [http://www.ncbi.nlm.nih.gov/pubmed/14578046?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Abstract]
Loiselle FB, Jaschke P, Casey JR. (2003). Structural and functional characterization of the human NBC3 sodium/bicarbonate co-transporter carboxyl-terminal cytoplasmic domain. ''Mol Membr Biol''. 20(4): 307-17. [http://www.ncbi.nlm.nih.gov/pubmed/14578046?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum Abstract] [[Media:Loiselle-2003-Mol Mem Biol.pdf|PDF]]


==Presentations==
Jaschke PR and Beatty JT. (2010). Out of the Blue. In a mutant lacking the magnesium-chelatase complex, we find zinc-bacteriochlorophyll incorporated into the photosystem and a new way to make bacteriochlorophyll. [[Media:Out_of_the_Blue-ICTPPO_2009.pdf|PDF]]
Jaschke PR and Beatty JT. (2007). Discovery of zinc-bacteriochlorophyll in ''Rhodobacter sphaeroides''. [[Media:ASM-Seattle_March_2007.pdf|PDF]]


==Useful links==
==Useful links==
[http://www.microbiology.ubc.ca/pjaschke Paul's Personal Page]
[http://www.mendeley.com/profiles/paul-jaschke/ Mendeley Profile]


[http://network.nature.com/people/pjaschke/profile Nature Networks Profile]
[http://www.linkedin.com/pub/paul-jaschke/15/688/269 LinkedIn Profile]
 
[http://en.wikipedia.org/wiki/Rhodobacter_sphaeroides ''Rhodobacter sphaeroides'' on Wikipedia]
 
==Other==
===Hobbies===
Beer Making


[http://www.linkedin.com/pub/paul-jaschke/15/688/269 LinkedIn Profile]
Snowboarding


[http://www.microbiology.ubc.ca/Beatty_Lab Beatty Lab Website]
Hiking & Camping

Latest revision as of 09:02, 17 January 2011

Redirect to:

Back to Lab Members

Paul Jaschke

Personal

Bio

I am currently a post-doc in Drew Endy's lab at Stanford University. The focus of my project is to redesign phage using both rational and combinatorial methods in order to finish the genetics of a simple system.

I started off my science career at the University of Alberta (Canada), working in the Casey and Michalak labs. Summer student work in the Casey Lab on the human sodium-bicarbonate co-transporter protein resulted in an authorship in a peer-reviewed publication. My honors project in the Michalak Lab had me determining the role of calcium signalling and calreticulin on murine embryonic stem cell differentiation. After achieving a B.Sc. (Honors) in Biochemistry in 2003 I went to the Beatty Lab at the University of British Columbia to start my Ph.D. While at UBC I discovered that a photosynthetic organism called Rhodobacter sphaeroides was capable of re-routing its chlorophyll biosynthetic machinery around a blockage to generate a new type of chlorophyll. November 2010 I was conferred a Ph.D in Microbiology and Immunology from UBC.

Contact Info

I work in the Endy Lab in the Department of Bioengineering

Education

2010 Ph.D. Microbiology and Immunology, University of British Columbia, Canada

2003 B.Sc. Honors Biochemistry, University of Alberta, Canada

Publications

Jaschke, PR. (2010). Discovery and characterization of a new zinc-bacteriochlorophyll biosynthetic pathway and photosystem in a magnesium-chelatase mutant. PhD Thesis. University of British Columbia. Abstract PDF

Lin S, Jaschke PR, Wang H, Paddock M, Tufts A, Allen JP, Rosell FI, Mauk GA, Woodbury NW, Beatty JT. (2009). Electron transfer in the Rhodobacter sphaeroides reaction center assembled with zinc bacteriochlorophyll. Proc Natl Acad Sci USA.106(21): 8537-42. Abstract PDF

Jaschke PR, LeBlanc HN, Lang AS, Beatty JT. (2008). The PucC protein of Rhodobacter capsulatus mitigates an inhibitory effect of light-harvesting 2 alpha and beta proteins on light-harvesting complex 1. Photosynth Res. 95(2-3): 279-84. Abstract PDF

Jaschke PR, Beatty JT. (2007). The photosystem of Rhodobacter sphaeroides assembles with zinc bacteriochlorophyll in a bchD (magnesium chelatase) mutant. Biochemistry. 46(43): 12491-500. Abstract PDF

Loiselle FB, Jaschke P, Casey JR. (2003). Structural and functional characterization of the human NBC3 sodium/bicarbonate co-transporter carboxyl-terminal cytoplasmic domain. Mol Membr Biol. 20(4): 307-17. Abstract PDF

Presentations

Jaschke PR and Beatty JT. (2010). Out of the Blue. In a mutant lacking the magnesium-chelatase complex, we find zinc-bacteriochlorophyll incorporated into the photosystem and a new way to make bacteriochlorophyll. PDF

Jaschke PR and Beatty JT. (2007). Discovery of zinc-bacteriochlorophyll in Rhodobacter sphaeroides. PDF

Useful links

Mendeley Profile

LinkedIn Profile

Rhodobacter sphaeroides on Wikipedia

Other

Hobbies

Beer Making

Snowboarding

Hiking & Camping

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