User:S. Saini
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Research interests
- Network Dynamics
- Statistics and Dynamics of Evolution in Microbial Populations
- Bacterial Pathogenesis
Openings
- Current Openings: (1) Modeling Dynamics and Statistics of Evolution (1 position, computational) (2) Evolution of Gene Regulatory Networks (1 position, experimental & computational). Students interested in PhD positions, or Thesis Projects should write to Supreet (saini AT che.iitb.ac.in) with a copy of their CV and research interests.
- Post doctoral researchers interested in exploring a possibility of working in the lab are requested to contact Supreet with their CV and a research proposal.
Research Group
Principal Investigator
- Supreet Saini (Assistant Professor) | PhD & MS (University of Illinois, Urbana-Champaign) | B.Tech. (IIT Delhi) | saini AT che.iitb.ac.in
Graduate Students (for PhD)
- Manish Kumar (2010 - date) | M.Tech. (Biomineral Processing) ISM Dhanbad | manish AT iitgn.ac.in [at IIT Gandhinagar]
- Mahendra Kumar Prajapat (2011 - date) | B.Tech. (Bioinformatics) Vellore Institute of Technology | prajapatmk.work AT gmail.com
- Kirti Jain (2011 - date) | MSc. (Life Science) NIT Rourkela | kirtijn1 AT gmail.com
- Debika Choudhury (2011 - date) | MSc. (Microbiology) University of Calcutta | debika217 AT gmail.com
- Chandrani Das (2012 - date) [with Dr. Sharmila Mande, TCS]
- Dinaker Vudhva (2014 - date) | MSc (Life Science) Jawaharlal Nehru University | dinakar.wadhwa AT gmail.com
Graduate Students (for Masters)
- Gouri Shankar Choudhary (2012 - date)
- Nitesh Meena (2013 - date)
Undergraduates
Project Research Fellows
Visiting Students
Past Members
Graduate Students (for Masters)
- Ashish (2012 - 2014) [Co-Founder, The Zero Games Pvt. Ltd, ashish.19766 AT gmail.com]
Project Research Staff
- Divyae Prasad (2014)
Undergraduates
- [2014] Piyush Lakhmani, Amit Aggarwal
- [2013] Chaitanya Gupta, Amit Pradhan
Visiting Students
- [2014] Sumedha Mangal (IIT BHU), Vaibhav Pathak (IIT BHU), Balaji Kumar (IIT Madras), Shriyam (Banasthali University)
Publications
- Elementary mode analysis reveals that Clostridium acetobutylicum modulates its metabolic strategy under external stress. Molecular BioSystems (2014)
- Acetone-butanol-ethanol fermentation analysis using only high performance liquid chromatography. Analytical Methods (2014)
- Characterization of Performance and Dynamics of Genetic Networks. IFAC Computer Applications in Biotechnology (2013)
- Role of feedback and network architecture in controlling virulence gene expression in Bordetella. Molecular BioSystems (2013)
- Role of extracellular cues to trigger the metabolic phase shifting from acidogenesis to solventogenesis in Clostridium acetobutylicum. Bioresource Technology (2013)
- Interplay between Fur and HNS in controlling virulence gene expression in Salmonella typhimurium. Computers in Biology and Medicine (2012)
- Continuous control of flagellar gene expression by the σ28-FlgM regulatory circuit in Salmonella enterica. Molecular Microbiology (2011)
- The interaction dynamics of a negative feedback loop regulates flagellar number in Salmonella enterica serovar Typhimurium. Molecular Microbiology (2010)
- FliZ induces a kinetic switch in flagellar gene expression. Journal of Bacteriology (2010)
- Role of cross talk in regulating the dynamic expression of the flagellar Salmonella pathogenicity island 1 and type 1 fimbrial genes. Journal of Bacteriology (2010)
- The role of coupled positive feedback in the expression of the SPI1 type three secretion system in Salmonella. PLoS Pathogens (2010)
- SprB is the molecular link between Salmonella pathogenicity island 1 (SPI1) and SPI4. Journal of Bacteriology (2010)
- Role of FimW, FimY, and FimZ in regulating the expression of type i fimbriae in Salmonella enterica serovar Typhimurium. Journal of Bacteriology (2009)
- Role of feedback loops in dictating flagellar gene regulation dynamics in Salmonella typhimurium. FOSBE Proceedings IET Systems Biology (2009)
- The rate of protein secretion dictates the temporal dynamics of flagellar gene expression. Molecular Microbiology (2008)
- FliZ Is a posttranslational activator of FlhD4C2-dependent flagellar gene expression. Journal of Bacteriology (2008)
- Pressure drop and heat transfer study in tube-in-tube helical heat exchanger. Chemical Engineering Science (2006)
Conference Presentations/Invited Talks
- Revisiting Demand Rules for Gene Regulation. Center for Excellence in Basic Sciences , Mumbai (2014)
- Characterizing Clostridium acetobutylicum metabolism using constraint-based modeling approach under stress. Clostridium XIII , China (2014)
- Revisiting Demand Rules for Gene Regulation. FEBS-EMBO Meeting , Paris (2014)
- Dynamic regulation of Pathogenicity Islands and Multiple Antibiotic Resistance loci in Salmonella typhimurium. FEBS-EMBO Meeting, Paris (2014)
- Logic of Interacting Quorum Sensing Systems in Bacteria. q-Bio, Santa Fe (2014)
- Introduction to Computational and Systems Biology. Workshop on Bioinformatics Applications and Interdisciplinary Technologies, Haffkine Institute , Mumbai (2014)
- Counting and control in bacteria via Secretion. Bacterial Expressions, NCBS (Bangalore) (2013)
- Impact of network map and architecture on gene expression dynamics. Foundations of Systems Biology in Engineering (FOSBE) , Tsuruoka (Japan) (2012)
- Dynamics and Control of the Clostridium acetobutylicum metabolic network. Clostridium XII , Nottingham (United Kingdom) (2012)
Contact
- Supreet Saini, Room 218, Assistant Professor, Chemical Engineering, IIT Bombay, Mumbai - 400 076 | Email: saini AT che.iitb.ac.in
- BioSystems Laboratory, Department of Chemical Engineering, IIT Bombay, Mumbai - 400 076 | Phone: 91 22 2576 4286