User:Sara Chuang

Protein and Metabolic Engineering

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Sara Chuang

• Sara Chuang
• skc2130@columbia.edu

• • PhD Candidate at Princeton University in Chemical and Biological Engineering
  • Undergraduate researcher in the Banta Protein Engineering Lab at Columbia University (2010-2013).

Education

• 2018 (expected), PhD, Chemical Engineering, Princeton University
• 2013, BS, Chemical Engineering, Columbia University

Publications

1. Campbell, E., Chuang, S., and Banta, S. (2013) “Modular exchange of substrate-binding loops alters both substrate and cofactor specificity in a member of the aldo-keto reductase superfamily” Protein Engineering, Design and Selection 26(3) 181-186.

Research interests

1. Protein Engineering
2. Pharmaceuticals
3. Drug Delivery

Research Projects

Current Project:

Past Projects:

• Analyzing interactions of super charged proteins on surfaces (2012-2013)
• Effects of protein stability on different surfaces (2011-2012)
• Mutating an enzyme for use in bio fuel cells (2010-2011)

Work Experience

• Drug Science Product Techology Summer Intern at Bristol Myers Squibb (Summer 2013)
  • Silicone Oil, Water and Protein Interactions
• Chemical Development Summer Intern at Bristol Myers Squibb (Summer 2012)
  • Scale-up of a Packed Bed Reactor

Research Skills

• Protein Expression in Ecoli
• Protein His Trap Purification
• FPLC (Fast Protein Liquid Chromatography)
• Protein Structure analysis on Circular Dichroism
• Gel electrophoresis
• PCR, Ligations
• Dynochem Modeling Software
• Aspen Modeling
• Micro-Flow Imaging