User:Slokwong: Difference between revisions
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| ==gene product== <br> | | ==gene product== <br> | ||
==molecular function== <br> | ==molecular function== <br> | ||
==systematic deletion== | ==systematic deletion== | ||
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Revision as of 13:39, 1 May 2007
Name: Sophie Wong
Major: Course 20
Email: slokwong AT mit DOT edu
User:Slokwong/MODULE 1 : Genome Engineering
Ada subunits | size,chromosome,null p-type | notes |
---|---|---|
Ada1 (aka HFI1, SUP110, SRM12, GAN1) | 1.467 kb/489 aa, Chr. XVI, viable |
==gene product== ==molecular function==
systematic deletion |
Gcn5 (aka ADA4, SWI9) | 1.32 kb/439aa, Chr. VII, viable |
==gene product== Ada histone acetyltransferase complex component molecular function
systematic deletion
|
Ada5 (aka SPT20) | 1.815 kb/604aa, Chr. XV, viable |
same as SPT20 |
Spt subunits | size, chromosome, null p-type | notes |
---|---|---|
Spt3 | 1.014 kb/337aa, Chr. IV, viable |
==gene product== ==molecular function== systematic deletion |
Spt7(aka GIT2) | 3.999 kb/1332aa, Chr. II, viable |
==gene product== histone acetyltransferase SAGA complex member
transcription factor systematic deletion
|
Spt8 | 1.809 kb/602aa, Chr. XII, viable |
==gene product== transcription factor molecular function
Systematic deletion
|
Spt20 (aka Ada5) | 1.815 kb/604aa, Chr. XV, viable |
==gene product== histone acetyltransferase SAGA complex member
transcription factor systematic deletions
|
TAF subunits | size, chromosome, null p-type | notes |
---|---|---|
TAF5 (aka TAF90) | 2.397 kb/798aa, Chr. II, inviable | ==gene product== ==molecular function== systematic deletion |
TAF6 (aka TAF60) | 1.551 kb/516aa, Chr. VII, inviable | ==gene product== TATA-binding protein-associated-factor
TafII60 |
TAF9 (aka TAF17) | 0.474 kb/157aa, Chr. XIII, inviable | ==gene product== TFIID subunit
TafII17 |
TAF10 (aka TAF23, TAF25) | 0.621 kb/206aa, Chr. IV, inviable | ==gene product== TFIID subunit
TafII25 |
TAF12(aka TAF61, TAF68) | 1.620 kb/539aa, Chr. IV, inviable | ==gene product== TFIID subunit
TafII61
TafII68 |
Tra1 subunit | size, chromosome, null p-type | notes |
---|---|---|
Tra1 | 11.235 kb/3744aa, Chr. VIII, inviable | Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation (1, 2, 3, 4) systematic deletion |
other subunits | size, chromosome, null p-type | notes |
---|---|---|
Sgf73 | 1.974 kb/657aa, Chr. VII , viable |
3 kDa subunit of SAGA histone acetyltransferase complex; involved in formation of the preinitiation complex assembly at promoters (1, 3) ==systematic deletion== viable |
Sgf29 | 0.779 kb/259aa, Chr. III, viable |
SaGa associated Factor 29kDa; Probable 29kKDa Subunit of SAGA histone acetyltransferase complex (1) ==systematic deletion== viable
|
Sgf11 | 0.3 kb/99aa, Chr.XVI, viable |
Integral subunit of SAGA histone acetyltransferase complex, regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation (1, 2) ==systematic deletion== viable |
Ubp8 | 1.416 kb/471aa, Chr. XIII, viable |
Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B (1, 2) ==systematic deletion== viable |
Sus1 | gene with intron, Chr. II, viable |
Protein involved in mRNA export coupled transcription activation; component of the SAGA histone acetylase complex (1) systematic deletion |