User:Steven J. Koch/MTC/April 19 2011: Difference between revisions
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(New page: Tuesday April 19, 2011. Microtubule gliding assay / kinesin modeling # Apology for being sick / missing so much. Reiterate the goals of the class #* Learn some molecular biophysics #* M...) |
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Tuesday April 19, 2011. Microtubule gliding assay / kinesin modeling | Tuesday April 19, 2011. Microtubule gliding assay / kinesin modeling | ||
* Apology for being sick / missing so much. Reiterate the goals of the class | |||
** Learn some molecular biophysics | |||
** More importantly: learn resources for doing molecular biophysics research (PDB, OpenWetWare, S30, Mendeley, Figshare, etc.) | |||
* Review of field trip -- watch movies! | |||
* Assignment due Tuesday April 26 | |||
* What is going on in gliding assay? | |||
** Andy video dissertation | |||
** Kinesin modeling (mostly Larry) | |||
*** Neck linker docking | |||
**** What is best way to model tension in the neck linker (chain of amino acids) | |||
**** '''GROUP WORK''': In the two-headed bound state, does neck-linker docking INCREASE or DECREASE or KEEP SAME the tension | |||
***** (A) Back head docks; (B) Front head docks | |||
***** Discuss with partner and make answers for (A) and (B) | |||
Revision as of 05:37, 19 April 2011
Tuesday April 19, 2011. Microtubule gliding assay / kinesin modeling
- Apology for being sick / missing so much. Reiterate the goals of the class
- Learn some molecular biophysics
- More importantly: learn resources for doing molecular biophysics research (PDB, OpenWetWare, S30, Mendeley, Figshare, etc.)
- Review of field trip -- watch movies!
- Assignment due Tuesday April 26
- What is going on in gliding assay?
- Andy video dissertation
- Kinesin modeling (mostly Larry)
- Neck linker docking
- What is best way to model tension in the neck linker (chain of amino acids)
- GROUP WORK: In the two-headed bound state, does neck-linker docking INCREASE or DECREASE or KEEP SAME the tension
- (A) Back head docks; (B) Front head docks
- Discuss with partner and make answers for (A) and (B)
- Neck linker docking
